PhosphoNET

           
Protein Info 
   
Short Name:  TRA2B
Full Name:  Transformer-2 protein homolog beta
Alias:  Arginine/serine-rich splicing factor 10; HTRA2- beta; HTRA2-beta; Htra2-beta; Splicing factor, arginine/serine-rich 10; TR2B; Transformer 2 beta; Transformer 2 protein homolog; Transformer 2-beta homologue; Transformer-2 protein homolog B; Transformer-2-beta
Type:  RNA binding protein, RNA splicing protein
Mass (Da):  33666
Number AA:  288
UniProt ID:  P62995
International Prot ID:  IPI00301503
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634     Uniprot OncoNet
Molecular Function:  GO:0003723  GO:0000166  GO:0005515 PhosphoSite+ KinaseNET
Biological Process:  GO:0000398     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S2______MSDSGEQNY
Site 2S4____MSDSGEQNYGE
Site 3Y9SDSGEQNYGERESRS
Site 4S14QNYGERESRSASRSG
Site 5S16YGERESRSASRSGSA
Site 6S18ERESRSASRSGSAHG
Site 7S20ESRSASRSGSAHGSG
Site 8S22RSASRSGSAHGSGKS
Site 9S26RSGSAHGSGKSARHT
Site 10S29SAHGSGKSARHTPAR
Site 11T33SGKSARHTPARSRSK
Site 12S37ARHTPARSRSKEDSR
Site 13S39HTPARSRSKEDSRRS
Site 14S43RSRSKEDSRRSRSKS
Site 15S46SKEDSRRSRSKSRSR
Site 16S48EDSRRSRSKSRSRSE
Site 17S50SRRSRSKSRSRSESR
Site 18S52RSRSKSRSRSESRSR
Site 19S54RSKSRSRSESRSRSR
Site 20S56KSRSRSESRSRSRRS
Site 21S58RSRSESRSRSRRSSR
Site 22S60RSESRSRSRRSSRRH
Site 23S63SRSRSRRSSRRHYTR
Site 24S64RSRSRRSSRRHYTRS
Site 25Y68RRSSRRHYTRSRSRS
Site 26T69RSSRRHYTRSRSRSR
Site 27S71SRRHYTRSRSRSRSH
Site 28S73RHYTRSRSRSRSHRR
Site 29S75YTRSRSRSRSHRRSR
Site 30S77RSRSRSRSHRRSRSR
Site 31S81RSRSHRRSRSRSYSR
Site 32S83RSHRRSRSRSYSRDY
Site 33S85HRRSRSRSYSRDYRR
Site 34Y86RRSRSRSYSRDYRRR
Site 35S87RSRSRSYSRDYRRRH
Site 36Y90SRSYSRDYRRRHSHS
Site 37S95RDYRRRHSHSHSPMS
Site 38S97YRRRHSHSHSPMSTR
Site 39S99RRHSHSHSPMSTRRR
Site 40S102SHSHSPMSTRRRHVG
Site 41T103HSHSPMSTRRRHVGN
Site 42Y128GVFGLSLYTTERDLR
Site 43T130FGLSLYTTERDLREV
Site 44S139RDLREVFSKYGPIAD
Site 45Y141LREVFSKYGPIADVS
Site 46S148YGPIADVSIVYDQQS
Site 47S155SIVYDQQSRRSRGFA
Site 48S158YDQQSRRSRGFAFVY
Site 49Y165SRGFAFVYFENVDDA
Site 50S194RRIRVDFSITKRPHT
Site 51T196IRVDFSITKRPHTPT
Site 52T201SITKRPHTPTPGIYM
Site 53T203TKRPHTPTPGIYMGR
Site 54Y207HTPTPGIYMGRPTYG
Site 55T212GIYMGRPTYGSSRRR
Site 56Y213IYMGRPTYGSSRRRD
Site 57S215MGRPTYGSSRRRDYY
Site 58S216GRPTYGSSRRRDYYD
Site 59Y221GSSRRRDYYDRGYDR
Site 60Y222SSRRRDYYDRGYDRG
Site 61Y226RDYYDRGYDRGYDDR
Site 62Y230DRGYDRGYDDRDYYS
Site 63Y235RGYDDRDYYSRSYRG
Site 64Y236GYDDRDYYSRSYRGG
Site 65S237YDDRDYYSRSYRGGG
Site 66S239DRDYYSRSYRGGGGG
Site 67Y240RDYYSRSYRGGGGGG
Site 68Y260AQDRDQIYRRRSPSP
Site 69S264DQIYRRRSPSPYYSR
Site 70S266IYRRRSPSPYYSRGG
Site 71Y268RRRSPSPYYSRGGYR
Site 72Y269RRSPSPYYSRGGYRS
Site 73S270RSPSPYYSRGGYRSR
Site 74Y274PYYSRGGYRSRSRSR
Site 75S276YSRGGYRSRSRSRSY
Site 76S278RGGYRSRSRSRSYSP
Site 77S280GYRSRSRSRSYSPRR
Site 78S282RSRSRSRSYSPRRY_
Site 79Y283SRSRSRSYSPRRY__
Site 80S284RSRSRSYSPRRY___
Site 81Y288RSYSPRRY_______
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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