KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
GNAI1
Full Name:
Guanine nucleotide-binding protein G(i) subunit alpha-1
Alias:
Adenylate cyclase-inhibiting G alpha; Gi; Gi1 alpha; Guanine nucleotide binding protein G, alpha inhibiting activity polypeptide 1; Guanine nucleotide-binding G
Type:
Intracellular, Plasma membrane, Heterotrimeric G-protein complex protein
Mass (Da):
40361
Number AA:
354
UniProt ID:
P63096
International Prot ID:
IPI00337415
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005834
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0003924
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007193
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
G
C
T
L
S
A
E
D
K
A
A
V
Site 2
S16
D
K
A
A
V
E
R
S
K
M
I
D
R
N
L
Site 3
S47
G
A
G
E
S
G
K
S
T
I
V
K
Q
M
K
Site 4
T48
A
G
E
S
G
K
S
T
I
V
K
Q
M
K
I
Site 5
Y61
K
I
I
H
E
A
G
Y
S
E
E
E
C
K
Q
Site 6
Y69
S
E
E
E
C
K
Q
Y
K
A
V
V
Y
S
N
Site 7
Y74
K
Q
Y
K
A
V
V
Y
S
N
T
I
Q
S
I
Site 8
S98
L
K
I
D
F
G
D
S
A
R
A
D
D
A
R
Site 9
S143
V
Q
A
C
F
N
R
S
R
E
Y
Q
L
N
D
Site 10
Y146
C
F
N
R
S
R
E
Y
Q
L
N
D
S
A
A
Site 11
S151
R
E
Y
Q
L
N
D
S
A
A
Y
Y
L
N
D
Site 12
Y154
Q
L
N
D
S
A
A
Y
Y
L
N
D
L
D
R
Site 13
Y155
L
N
D
S
A
A
Y
Y
L
N
D
L
D
R
I
Site 14
Y167
D
R
I
A
Q
P
N
Y
I
P
T
Q
Q
D
V
Site 15
T181
V
L
R
T
R
V
K
T
T
G
I
V
E
T
H
Site 16
S206
F
D
V
G
G
Q
R
S
E
R
K
K
W
I
H
Site 17
S281
F
E
E
K
I
K
K
S
P
L
T
I
C
Y
P
Site 18
T284
K
I
K
K
S
P
L
T
I
C
Y
P
E
Y
A
Site 19
Y287
K
S
P
L
T
I
C
Y
P
E
Y
A
G
S
N
Site 20
Y290
L
T
I
C
Y
P
E
Y
A
G
S
N
T
Y
E
Site 21
S293
C
Y
P
E
Y
A
G
S
N
T
Y
E
E
A
A
Site 22
Y302
T
Y
E
E
A
A
A
Y
I
Q
C
Q
F
E
D
Site 23
T316
D
L
N
K
R
K
D
T
K
E
I
Y
T
H
F
Site 24
Y320
R
K
D
T
K
E
I
Y
T
H
F
T
C
A
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation