PhosphoNET

           
Protein Info 
   
Short Name:  HERV-K_6q14.1 provirus ancestral Gag-Pol polyprotein
Full Name:  HERV-K_6q14.1 provirus ancestral Gag-Pol polyprotein
Alias:  HERV-K(C6) Gag-Pol protein;HERV-K109 Gag-Pol protein;PR;Retropepsin;p66 RT
Type: 
Mass (Da):  123620
Number AA:  1117
UniProt ID:  P63128
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S10QTKSKIKSKYASYLS
Site 2Y12KSKIKSKYASYLSFI
Site 3S14KIKSKYASYLSFIKI
Site 4T97AALEPFQTEEDSISV
Site 5S101PFQTEEDSISVSDAP
Site 6S103QTEEDSISVSDAPGS
Site 7S105EEDSISVSDAPGSGI
Site 8S110SVSDAPGSGIIDCNE
Site 9T119IIDCNEKTRKKSQKE
Site 10S123NEKTRKKSQKETESL
Site 11T127RKKSQKETESLHCEY
Site 12S129KSQKETESLHCEYVA
Site 13Y149QSTQNVDYNQLQEVI
Site 14Y157NQLQEVIYPETLKLE
Site 15S174GPELVGPSESKPRGT
Site 16S176ELVGPSESKPRGTSP
Site 17T181SESKPRGTSPLPAGQ
Site 18S182ESKPRGTSPLPAGQV
Site 19T192PAGQVPVTLQPQKQV
Site 20T204KQVKENKTQPPVAYQ
Site 21Y212QPPVAYQYWPPAELQ
Site 22Y220WPPAELQYRPPPESQ
Site 23S226QYRPPPESQYGYPGM
Site 24Y228RPPPESQYGYPGMPP
Site 25Y230PPESQYGYPGMPPAP
Site 26Y243APQGRAPYPQPPTRR
Site 27T248APYPQPPTRRLNPTA
Site 28T254PTRRLNPTAPPSRQG
Site 29S258LNPTAPPSRQGSELH
Site 30S262APPSRQGSELHEIID
Site 31S271LHEIIDKSRKEGDTE
Site 32T277KSRKEGDTEAWQFPV
Site 33T285EAWQFPVTLEPMPPG
Site 34T302AQEGEPPTVEARYKS
Site 35Y307PPTVEARYKSFSIKI
Site 36S309TVEARYKSFSIKILK
Site 37S311EARYKSFSIKILKDM
Site 38Y325MKEGVKQYGPNSPYM
Site 39S329VKQYGPNSPYMRTLL
Site 40Y331QYGPNSPYMRTLLDS
Site 41T334PNSPYMRTLLDSIAH
Site 42S338YMRTLLDSIAHGHRL
Site 43Y348HGHRLIPYDWEILAK
Site 44S356DWEILAKSSLSPSQF
Site 45S361AKSSLSPSQFLQFKT
Site 46S403LGIGQNWSTISQQAL
Site 47S435EKIQDPGSTCPSFNT
Site 48S439DPGSTCPSFNTVRQG
Site 49T442STCPSFNTVRQGSKE
Site 50S447FNTVRQGSKEPYPDF
Site 51Y451RQGSKEPYPDFVARL
Site 52S465LQDVAQKSIADEKAR
Site 53S503KGKVPAGSDVISEYV
Site 54S507PAGSDVISEYVKACD
Site 55T541VLGGQVRTFGGKCYN
Site 56Y547RTFGGKCYNCGQIGH
Site 57S593KKGKHWASQCRSKFD
Site 58S607DKNGQPLSGNEQRGQ
Site 59S642QGQQPPLSQVFQGIS
Site 60S649SQVFQGISQLPQYNN
Site 61Y654GISQLPQYNNCPPPQ
Site 62T688EPPQKIPTGVYGPLP
Site 63S718KGVQIHTSVVDSDYK
Site 64S722IHTSVVDSDYKGEIQ
Site 65Y724TSVVDSDYKGEIQLV
Site 66S739ISSSVPWSASPGDRI
Site 67S741SSVPWSASPGDRIAQ
Site 68S760PYIKGGNSEIKRIGG
Site 69S770KRIGGLGSTDPTGKA
Site 70S782GKAAYWASQVSENRP
Site 71T858GPDNQESTVQPMITS
Site 72Y890ITMPAPLYSPTSQKI
Site 73S891TMPAPLYSPTSQKIM
Site 74S894APLYSPTSQKIMTKR
Site 75T899PTSQKIMTKRGYIPG
Site 76Y903KIMTKRGYIPGKGLG
Site 77Y933QKREGIGYPFLGAAT
Site 78T950PPKPIPLTWKTEKPV
Site 79S988EKGHIEPSFSPWNSP
Site 80S990GHIEPSFSPWNSPVF
Site 81S994PSFSPWNSPVFVIQK
Site 82T1010SGKWRMLTDLRAVNA
Site 83S1031PLQPGLPSPAMIPKD
Site 84T1097NSPTICQTFVGRALQ
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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