KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
HERV-K_22q11.21 provirus ancestral Gag polyprotein
Full Name:
HERV-K_22q11.21 provirus ancestral Gag polyprotein
Alias:
HERV-K101 Gag protein
Type:
Mass (Da):
74040
Number AA:
666
UniProt ID:
P63145
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
Q
T
K
S
K
I
K
S
K
Y
A
S
Y
L
S
Site 2
Y12
K
S
K
I
K
S
K
Y
A
S
Y
L
S
F
I
Site 3
S14
K
I
K
S
K
Y
A
S
Y
L
S
F
I
K
I
Site 4
T97
A
A
L
E
P
F
Q
T
E
E
D
S
V
S
V
Site 5
S101
P
F
Q
T
E
E
D
S
V
S
V
S
D
A
P
Site 6
S103
Q
T
E
E
D
S
V
S
V
S
D
A
P
G
S
Site 7
S105
E
E
D
S
V
S
V
S
D
A
P
G
S
C
L
Site 8
S110
S
V
S
D
A
P
G
S
C
L
I
D
C
N
E
Site 9
T119
L
I
D
C
N
E
K
T
R
K
K
S
Q
K
E
Site 10
S123
N
E
K
T
R
K
K
S
Q
K
E
T
E
S
L
Site 11
T127
R
K
K
S
Q
K
E
T
E
S
L
H
C
E
Y
Site 12
S129
K
S
Q
K
E
T
E
S
L
H
C
E
Y
V
A
Site 13
Y149
Q
S
T
Q
N
V
D
Y
N
Q
L
Q
E
V
I
Site 14
Y157
N
Q
L
Q
E
V
I
Y
P
E
T
L
K
L
E
Site 15
S174
G
P
E
L
V
G
P
S
E
S
K
P
R
G
T
Site 16
S176
E
L
V
G
P
S
E
S
K
P
R
G
T
S
P
Site 17
T181
S
E
S
K
P
R
G
T
S
P
L
P
A
G
Q
Site 18
S182
E
S
K
P
R
G
T
S
P
L
P
A
G
Q
V
Site 19
T192
P
A
G
Q
V
P
V
T
L
Q
P
Q
K
Q
V
Site 20
T204
K
Q
V
K
E
N
K
T
Q
P
P
V
A
Y
Q
Site 21
Y212
Q
P
P
V
A
Y
Q
Y
W
P
P
A
E
L
Q
Site 22
Y220
W
P
P
A
E
L
Q
Y
R
P
P
P
E
S
Q
Site 23
S226
Q
Y
R
P
P
P
E
S
Q
Y
G
Y
P
G
M
Site 24
Y228
R
P
P
P
E
S
Q
Y
G
Y
P
G
M
P
P
Site 25
Y230
P
P
E
S
Q
Y
G
Y
P
G
M
P
P
A
P
Site 26
Y243
A
P
Q
G
R
A
P
Y
P
Q
P
P
T
R
R
Site 27
T248
A
P
Y
P
Q
P
P
T
R
R
L
N
P
T
A
Site 28
T254
P
T
R
R
L
N
P
T
A
P
P
S
R
Q
G
Site 29
S258
L
N
P
T
A
P
P
S
R
Q
G
S
E
L
H
Site 30
S262
A
P
P
S
R
Q
G
S
E
L
H
E
I
I
D
Site 31
S271
L
H
E
I
I
D
K
S
R
K
E
G
D
T
E
Site 32
T277
K
S
R
K
E
G
D
T
E
A
W
Q
F
P
V
Site 33
T285
E
A
W
Q
F
P
V
T
L
E
P
M
P
P
G
Site 34
T302
A
Q
E
G
E
P
P
T
V
E
A
R
Y
K
S
Site 35
Y307
P
P
T
V
E
A
R
Y
K
S
F
S
I
K
M
Site 36
S309
T
V
E
A
R
Y
K
S
F
S
I
K
M
L
K
Site 37
S311
E
A
R
Y
K
S
F
S
I
K
M
L
K
D
M
Site 38
Y325
M
K
E
G
V
K
Q
Y
G
P
N
S
P
Y
M
Site 39
S329
V
K
Q
Y
G
P
N
S
P
Y
M
R
T
L
L
Site 40
Y331
Q
Y
G
P
N
S
P
Y
M
R
T
L
L
D
S
Site 41
T334
P
N
S
P
Y
M
R
T
L
L
D
S
I
A
Y
Site 42
S338
Y
M
R
T
L
L
D
S
I
A
Y
G
H
R
L
Site 43
Y348
Y
G
H
R
L
I
P
Y
D
W
E
I
L
A
K
Site 44
S356
D
W
E
I
L
A
K
S
S
L
S
P
S
Q
F
Site 45
S361
A
K
S
S
L
S
P
S
Q
F
L
Q
F
K
T
Site 46
S403
L
G
I
G
Q
N
W
S
T
I
S
Q
Q
A
L
Site 47
S435
E
K
I
Q
D
P
G
S
A
C
P
S
F
N
T
Site 48
S439
D
P
G
S
A
C
P
S
F
N
T
V
R
Q
G
Site 49
T442
S
A
C
P
S
F
N
T
V
R
Q
G
S
K
E
Site 50
S447
F
N
T
V
R
Q
G
S
K
E
P
Y
P
D
F
Site 51
Y451
R
Q
G
S
K
E
P
Y
P
D
F
V
A
R
L
Site 52
S465
L
Q
D
V
A
Q
K
S
I
A
D
E
K
A
R
Site 53
S503
K
G
K
V
P
A
G
S
D
V
I
S
E
Y
V
Site 54
S507
P
A
G
S
D
V
I
S
E
Y
V
K
A
C
D
Site 55
T541
V
L
G
G
Q
V
R
T
F
G
G
K
C
Y
N
Site 56
Y547
R
T
F
G
G
K
C
Y
N
C
G
Q
I
G
H
Site 57
S593
K
K
G
K
H
W
A
S
Q
C
R
S
K
F
D
Site 58
S607
D
K
N
G
Q
P
L
S
G
N
E
Q
R
G
Q
Site 59
S642
Q
G
Q
Q
P
P
L
S
Q
V
F
Q
G
I
S
Site 60
S649
S
Q
V
F
Q
G
I
S
Q
L
P
Q
Y
N
N
Site 61
Y654
G
I
S
Q
L
P
Q
Y
N
N
C
P
L
P
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation