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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HR6B
Full Name:
Ubiquitin-conjugating enzyme E2 B
Alias:
E2-17 kDa; EC 6.3.2.19; RAD6B; UBC2; UBE2B; Ubiquitin carrier protein B; Ubiquitin-conjugating enzyme E2B, RAD6 homology; Ubiquitin-protein ligase B
Type:
Chromatin, Plasma membrane, Nucleus protein
Mass (Da):
17312
Number AA:
152
UniProt ID:
P63146
International Prot ID:
IPI00012060
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000785
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0031625
GO:0004842
PhosphoSite+
KinaseNET
Biological Process:
GO:0060070
GO:0033522
GO:0006301
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
E
D
P
P
V
G
V
S
G
A
P
S
E
N
N
Site 2
S29
V
G
V
S
G
A
P
S
E
N
N
I
M
Q
W
Site 3
S60
F
K
L
V
I
E
F
S
E
E
Y
P
N
K
P
Site 4
Y63
V
I
E
F
S
E
E
Y
P
N
K
P
P
T
V
Site 5
T69
E
Y
P
N
K
P
P
T
V
R
F
L
S
K
M
Site 6
S74
P
P
T
V
R
F
L
S
K
M
F
H
P
N
V
Site 7
S97
D
I
L
Q
N
R
W
S
P
T
Y
D
V
S
S
Site 8
T99
L
Q
N
R
W
S
P
T
Y
D
V
S
S
I
L
Site 9
Y100
Q
N
R
W
S
P
T
Y
D
V
S
S
I
L
T
Site 10
S103
W
S
P
T
Y
D
V
S
S
I
L
T
S
I
Q
Site 11
S104
S
P
T
Y
D
V
S
S
I
L
T
S
I
Q
S
Site 12
S111
S
I
L
T
S
I
Q
S
L
L
D
E
P
N
P
Site 13
S120
L
D
E
P
N
P
N
S
P
A
N
S
Q
A
A
Site 14
S124
N
P
N
S
P
A
N
S
Q
A
A
Q
L
Y
Q
Site 15
Y130
N
S
Q
A
A
Q
L
Y
Q
E
N
K
R
E
Y
Site 16
Y137
Y
Q
E
N
K
R
E
Y
E
K
R
V
S
A
I
Site 17
S142
R
E
Y
E
K
R
V
S
A
I
V
E
Q
S
W
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation