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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NOP14
Full Name:
Nucleolar protein 14
Alias:
Chromosome 4 open reading frame 9; NOL14; NOP14 nucleolar protein; Nucleolar complex protein 14; RES4-25
Type:
Mass (Da):
97668
Number AA:
857
UniProt ID:
P78316
International Prot ID:
IPI00022613
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005730
GO:0005730
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0030515
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0030490
GO:0042274
GO:0006396
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
V
G
A
R
R
K
A
S
G
A
P
A
G
A
R
Site 2
S29
G
G
P
A
K
A
N
S
N
P
F
E
V
K
V
Site 3
T48
F
Q
I
L
G
R
K
T
R
H
D
V
G
L
P
Site 4
T67
A
R
A
L
R
K
R
T
Q
T
L
L
K
E
Y
Site 5
T69
A
L
R
K
R
T
Q
T
L
L
K
E
Y
K
E
Site 6
Y74
T
Q
T
L
L
K
E
Y
K
E
R
D
K
S
N
Site 7
S80
E
Y
K
E
R
D
K
S
N
V
F
R
D
K
R
Site 8
Y91
R
D
K
R
F
G
E
Y
N
S
N
M
S
P
E
Site 9
S93
K
R
F
G
E
Y
N
S
N
M
S
P
E
E
K
Site 10
S96
G
E
Y
N
S
N
M
S
P
E
E
K
M
M
K
Site 11
Y130
E
D
E
E
L
T
H
Y
G
Q
S
L
A
D
I
Site 12
S133
E
L
T
H
Y
G
Q
S
L
A
D
I
E
K
H
Site 13
S146
K
H
N
D
I
V
D
S
D
S
D
A
E
D
R
Site 14
S148
N
D
I
V
D
S
D
S
D
A
E
D
R
G
T
Site 15
T155
S
D
A
E
D
R
G
T
L
S
A
E
L
T
A
Site 16
S157
A
E
D
R
G
T
L
S
A
E
L
T
A
A
H
Site 17
T161
G
T
L
S
A
E
L
T
A
A
H
F
G
G
G
Site 18
T176
G
G
L
L
H
K
K
T
Q
Q
E
G
E
E
R
Site 19
S188
E
E
R
E
K
P
K
S
R
K
E
L
I
E
E
Site 20
S200
I
E
E
L
I
A
K
S
K
Q
E
K
R
E
R
Site 21
S233
K
E
I
Q
T
L
L
S
H
K
T
P
K
S
E
Site 22
T236
Q
T
L
L
S
H
K
T
P
K
S
E
N
R
D
Site 23
S239
L
S
H
K
T
P
K
S
E
N
R
D
K
K
E
Site 24
Y253
E
K
P
K
P
D
A
Y
D
M
M
V
R
E
L
Site 25
S269
F
E
M
K
A
Q
P
S
N
R
M
K
T
E
A
Site 26
T274
Q
P
S
N
R
M
K
T
E
A
E
L
A
K
E
Site 27
S313
V
K
K
P
K
H
M
S
A
D
D
L
N
D
G
Site 28
S332
K
D
D
R
R
L
L
S
Y
K
D
G
K
M
N
Site 29
Y333
D
D
R
R
L
L
S
Y
K
D
G
K
M
N
V
Site 30
S349
E
D
V
Q
E
E
Q
S
K
E
A
S
D
P
E
Site 31
S353
E
E
Q
S
K
E
A
S
D
P
E
S
N
E
E
Site 32
S357
K
E
A
S
D
P
E
S
N
E
E
E
G
D
S
Site 33
S364
S
N
E
E
E
G
D
S
S
G
G
E
D
T
E
Site 34
S365
N
E
E
E
G
D
S
S
G
G
E
D
T
E
E
Site 35
T370
D
S
S
G
G
E
D
T
E
E
S
D
S
P
D
Site 36
S373
G
G
E
D
T
E
E
S
D
S
P
D
S
H
L
Site 37
S375
E
D
T
E
E
S
D
S
P
D
S
H
L
D
L
Site 38
S378
E
E
S
D
S
P
D
S
H
L
D
L
E
S
N
Site 39
S384
D
S
H
L
D
L
E
S
N
V
E
S
E
E
E
Site 40
S388
D
L
E
S
N
V
E
S
E
E
E
N
E
K
P
Site 41
T402
P
A
K
E
Q
R
Q
T
P
G
K
G
L
I
S
Site 42
T418
K
E
R
A
G
K
A
T
R
D
E
L
P
Y
T
Site 43
Y424
A
T
R
D
E
L
P
Y
T
F
A
A
P
E
S
Site 44
T425
T
R
D
E
L
P
Y
T
F
A
A
P
E
S
Y
Site 45
S431
Y
T
F
A
A
P
E
S
Y
E
E
L
R
S
L
Site 46
S437
E
S
Y
E
E
L
R
S
L
L
L
G
R
S
M
Site 47
T486
E
Y
V
G
D
L
A
T
D
D
P
P
D
L
T
Site 48
T534
E
M
E
E
M
I
E
T
K
G
R
A
A
L
P
Site 49
S629
I
A
T
P
N
K
A
S
Q
G
S
T
L
V
H
Site 50
T633
N
K
A
S
Q
G
S
T
L
V
H
P
F
R
A
Site 51
T658
S
A
R
E
D
V
A
T
W
Q
Q
S
S
L
S
Site 52
S663
V
A
T
W
Q
Q
S
S
L
S
L
R
W
A
S
Site 53
S665
T
W
Q
Q
S
S
L
S
L
R
W
A
S
R
L
Site 54
S670
S
L
S
L
R
W
A
S
R
L
R
A
P
T
S
Site 55
T676
A
S
R
L
R
A
P
T
S
T
E
A
N
H
I
Site 56
S677
S
R
L
R
A
P
T
S
T
E
A
N
H
I
R
Site 57
T678
R
L
R
A
P
T
S
T
E
A
N
H
I
R
L
Site 58
S727
T
D
H
L
A
D
C
S
H
P
Q
E
L
Q
E
Site 59
S738
E
L
Q
E
L
C
Q
S
T
L
T
E
M
E
S
Site 60
T741
E
L
C
Q
S
T
L
T
E
M
E
S
Q
K
Q
Site 61
S745
S
T
L
T
E
M
E
S
Q
K
Q
L
C
R
P
Site 62
T754
K
Q
L
C
R
P
L
T
C
E
K
S
K
P
V
Site 63
S758
R
P
L
T
C
E
K
S
K
P
V
P
L
K
L
Site 64
T767
P
V
P
L
K
L
F
T
P
R
L
V
K
V
L
Site 65
S783
F
G
R
K
Q
G
S
S
K
E
E
Q
E
R
K
Site 66
S839
K
V
K
Q
L
F
N
S
L
A
T
Q
E
G
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation