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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GPC5
Full Name:
Glypican-5
Alias:
glypican 5; glypican proteoglycan 5; glypican-5
Type:
Cell surface
Mass (Da):
63707
Number AA:
572
UniProt ID:
P78333
International Prot ID:
IPI00019180
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0031225
GO:0005615
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0043395
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T29
A
R
S
E
G
V
Q
T
C
E
E
V
R
K
L
Site 2
S51
A
V
R
G
L
P
D
S
P
R
A
G
P
D
L
Site 3
T113
A
F
Q
E
T
L
E
T
L
I
K
Q
A
E
N
Site 4
S186
I
N
P
G
V
T
D
S
S
L
E
Y
S
E
C
Site 5
S187
N
P
G
V
T
D
S
S
L
E
Y
S
E
C
I
Site 6
Y190
V
T
D
S
S
L
E
Y
S
E
C
I
R
M
A
Site 7
S191
T
D
S
S
L
E
Y
S
E
C
I
R
M
A
R
Site 8
S202
R
M
A
R
R
D
V
S
P
F
G
N
I
P
Q
Site 9
S218
V
M
G
Q
M
G
R
S
L
L
P
S
R
T
F
Site 10
T224
R
S
L
L
P
S
R
T
F
L
Q
A
L
N
L
Site 11
Y241
E
V
I
N
T
T
D
Y
L
H
F
S
K
E
C
Site 12
S245
T
T
D
Y
L
H
F
S
K
E
C
S
R
A
L
Site 13
S249
L
H
F
S
K
E
C
S
R
A
L
L
K
M
Q
Site 14
Y257
R
A
L
L
K
M
Q
Y
C
P
H
C
Q
G
L
Site 15
Y295
L
N
P
H
W
H
A
Y
I
R
S
L
E
E
L
Site 16
S298
H
W
H
A
Y
I
R
S
L
E
E
L
S
D
A
Site 17
S303
I
R
S
L
E
E
L
S
D
A
M
H
G
T
Y
Site 18
T351
I
C
G
R
P
V
R
T
P
T
Q
S
P
R
C
Site 19
T353
G
R
P
V
R
T
P
T
Q
S
P
R
C
S
F
Site 20
S355
P
V
R
T
P
T
Q
S
P
R
C
S
F
D
Q
Site 21
S359
P
T
Q
S
P
R
C
S
F
D
Q
S
K
E
K
Site 22
S363
P
R
C
S
F
D
Q
S
K
E
K
H
G
M
K
Site 23
T371
K
E
K
H
G
M
K
T
T
T
R
N
S
E
E
Site 24
T372
E
K
H
G
M
K
T
T
T
R
N
S
E
E
T
Site 25
S376
M
K
T
T
T
R
N
S
E
E
T
L
A
N
R
Site 26
T379
T
T
R
N
S
E
E
T
L
A
N
R
R
K
E
Site 27
S390
R
R
K
E
F
I
N
S
L
R
L
Y
R
S
F
Site 28
Y394
F
I
N
S
L
R
L
Y
R
S
F
Y
G
G
L
Site 29
S396
N
S
L
R
L
Y
R
S
F
Y
G
G
L
A
D
Site 30
Y398
L
R
L
Y
R
S
F
Y
G
G
L
A
D
Q
L
Site 31
S427
N
G
E
D
I
V
K
S
Y
T
Q
R
V
V
G
Site 32
T429
E
D
I
V
K
S
Y
T
Q
R
V
V
G
N
G
Site 33
S473
V
Q
L
L
Q
G
R
S
P
K
P
D
K
W
E
Site 34
S507
D
E
D
G
C
G
G
S
G
S
G
E
V
K
R
Site 35
S509
D
G
C
G
G
S
G
S
G
E
V
K
R
T
L
Site 36
T515
G
S
G
E
V
K
R
T
L
K
I
T
D
W
M
Site 37
T537
D
V
K
Q
I
H
Q
T
D
T
G
S
T
L
D
Site 38
S541
I
H
Q
T
D
T
G
S
T
L
D
T
T
G
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation