PhosphoNET

           
Protein Info 
   
Short Name:  EIF4G2
Full Name:  Eukaryotic translation initiation factor 4 gamma 2
Alias:  DAP5; Death associated protein 5; EIF4G 2; EIF-4G 2; EIF-4-gamma 2; Eukaryotic translation initiation factor 4 gamma, 2; IF4G2; NAT1; Novel APOBEC-1 target 1; P97; Translation repressor NAT1
Type:  Translation protein, initiation complex
Mass (Da):  102362
Number AA:  907
UniProt ID:  P78344
International Prot ID:  IPI00015952
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016281  GO:0032991  GO:0043234 Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0003743  GO:0005488 PhosphoSite+ KinaseNET
Biological Process:  GO:0016070  GO:0007050  GO:0008219 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S3_____MESAIAEGGA
Site 2S11AIAEGGASRFSASSG
Site 3S14EGGASRFSASSGGGG
Site 4S16GASRFSASSGGGGSR
Site 5S17ASRFSASSGGGGSRG
Site 6S22ASSGGGGSRGAPQHY
Site 7Y29SRGAPQHYPKTAGNS
Site 8T32APQHYPKTAGNSEFL
Site 9T42NSEFLGKTPGQNAQK
Site 10S55QKWIPARSTRRDDNS
Site 11T56KWIPARSTRRDDNSA
Site 12S62STRRDDNSAANNSAN
Site 13T89RGILNKLTPEKFDKL
Site 14Y128KALEEPKYSSLYAQL
Site 15S130LEEPKYSSLYAQLCL
Site 16Y132EPKYSSLYAQLCLRL
Site 17S160GQPGQKQSTTFRRLL
Site 18T162PGQKQSTTFRRLLIS
Site 19S169TFRRLLISKLQDEFE
Site 20Y185RTRNVDVYDKRENPL
Site 21S226KLDLIHESILHKCIK
Site 22S272LDHERAKSLMDQYFA
Site 23Y277AKSLMDQYFARMCSL
Site 24S283QYFARMCSLMLSKEL
Site 25T301IRFLLQDTVELREHH
Site 26T322FLDNGPKTINQIRQD
Site 27S348PMAQGMRSDFFLEGP
Site 28S381MFGQMPGSGIGTGPG
Site 29T385MPGSGIGTGPGVIQD
Site 30S395GVIQDRFSPTMGRHR
Site 31T397IQDRFSPTMGRHRSN
Site 32S403PTMGRHRSNQLFNGH
Site 33T418GGHIMPPTQSQFGEM
Site 34S420HIMPPTQSQFGEMGG
Site 35S432MGGKFMKSQGLSQLY
Site 36S436FMKSQGLSQLYHNQS
Site 37Y439SQGLSQLYHNQSQGL
Site 38S443SQLYHNQSQGLLSQL
Site 39S448NQSQGLLSQLQGQSK
Site 40S454LSQLQGQSKDMPPRF
Site 41S462KDMPPRFSKKGQLNA
Site 42S473QLNADEISLRPAQSF
Site 43S479ISLRPAQSFLMNKNQ
Site 44T495PKLQPQITMIPPSAQ
Site 45S500QITMIPPSAQPPRTQ
Site 46T506PSAQPPRTQTPPLGQ
Site 47T508AQPPRTQTPPLGQTP
Site 48T514QTPPLGQTPQLGLKT
Site 49T521TPQLGLKTNPPLIQE
Site 50S534QEKPAKTSKKPPPSK
Site 51S540TSKKPPPSKEELLKL
Site 52T553KLTETVVTEYLNSGN
Site 53Y555TETVVTEYLNSGNAN
Site 54S558VVTEYLNSGNANEAV
Site 55S589LSKVIILSLDRSDED
Site 56S593IILSLDRSDEDKEKA
Site 57S601DEDKEKASSLISLLK
Site 58S602EDKEKASSLISLLKQ
Site 59S605EKASSLISLLKQEGI
Site 60T614LKQEGIATSDNFMQA
Site 61S615KQEGIATSDNFMQAF
Site 62S641VDIPLVKSYLAQFAA
Site 63Y642DIPLVKSYLAQFAAR
Site 64S667ELAQPLESGTHFPLF
Site 65S746KQIKLDPSPQTIYKW
Site 66Y751DPSPQTIYKWIKDNI
Site 67S759KWIKDNISPKLHVDK
Site 68S781TSFLQYISSEVNPPS
Site 69S782SFLQYISSEVNPPSD
Site 70S788SSEVNPPSDETDSSS
Site 71T791VNPPSDETDSSSAPS
Site 72S793PPSDETDSSSAPSKE
Site 73S794PSDETDSSSAPSKEQ
Site 74S795SDETDSSSAPSKEQL
Site 75S798TDSSSAPSKEQLEQE
Site 76S811QEKQLLLSFKPVMQK
Site 77Y839YALQVHCYNSNFPKG
Site 78T874LAWKEDITQEFPGKG
Site 79T896QWLTWLETAEEEESE
Site 80S902ETAEEEESEEEAD__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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