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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCNA1
Full Name:
Cyclin-A1
Alias:
Type:
Mass (Da):
52358
Number AA:
465
UniProt ID:
P78396
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y22
I
G
G
W
G
E
E
Y
L
S
W
E
G
P
G
Site 2
S24
G
W
G
E
E
Y
L
S
W
E
G
P
G
L
P
Site 3
S48
E
S
E
A
M
H
C
S
N
P
K
S
G
V
V
Site 4
T70
P
D
A
C
Q
I
L
T
R
A
P
L
G
Q
D
Site 5
Y93
L
L
T
A
N
G
Q
Y
R
R
T
C
G
Q
G
Site 6
T96
A
N
G
Q
Y
R
R
T
C
G
Q
G
I
T
R
Site 7
Y107
G
I
T
R
I
R
C
Y
S
G
S
E
N
A
F
Site 8
S108
I
T
R
I
R
C
Y
S
G
S
E
N
A
F
P
Site 9
S110
R
I
R
C
Y
S
G
S
E
N
A
F
P
P
A
Site 10
Y138
P
K
Q
G
F
D
I
Y
M
D
E
L
E
Q
G
Site 11
S149
L
E
Q
G
D
R
D
S
C
S
V
R
E
G
M
Site 12
S151
Q
G
D
R
D
S
C
S
V
R
E
G
M
A
F
Site 13
T168
V
Y
E
V
D
T
G
T
L
K
S
D
L
H
F
Site 14
S190
S
P
M
L
V
D
S
S
L
L
S
Q
S
E
D
Site 15
S193
L
V
D
S
S
L
L
S
Q
S
E
D
I
S
S
Site 16
S195
D
S
S
L
L
S
Q
S
E
D
I
S
S
L
G
Site 17
S199
L
S
Q
S
E
D
I
S
S
L
G
T
D
V
I
Site 18
S200
S
Q
S
E
D
I
S
S
L
G
T
D
V
I
N
Site 19
T203
E
D
I
S
S
L
G
T
D
V
I
N
V
T
E
Site 20
Y211
D
V
I
N
V
T
E
Y
A
E
E
I
Y
Q
Y
Site 21
Y218
Y
A
E
E
I
Y
Q
Y
L
R
E
A
E
I
R
Site 22
Y232
R
H
R
P
K
A
H
Y
M
K
K
Q
P
D
I
Site 23
T240
M
K
K
Q
P
D
I
T
E
G
M
R
T
I
L
Site 24
T264
E
Y
K
L
R
A
E
T
L
Y
L
A
V
N
F
Site 25
S280
D
R
F
L
S
C
M
S
V
L
R
G
K
L
Q
Site 26
Y300
A
M
L
L
A
S
K
Y
E
E
I
Y
P
P
E
Site 27
Y304
A
S
K
Y
E
E
I
Y
P
P
E
V
D
E
F
Site 28
Y313
P
E
V
D
E
F
V
Y
I
T
D
D
T
Y
T
Site 29
T318
F
V
Y
I
T
D
D
T
Y
T
K
R
Q
L
L
Site 30
Y319
V
Y
I
T
D
D
T
Y
T
K
R
Q
L
L
K
Site 31
T320
Y
I
T
D
D
T
Y
T
K
R
Q
L
L
K
M
Site 32
Y351
T
N
Q
F
L
L
Q
Y
L
R
R
Q
G
V
C
Site 33
Y367
R
T
E
N
L
A
K
Y
V
A
E
L
S
L
L
Site 34
T407
N
K
H
F
W
P
E
T
L
A
A
F
T
G
Y
Site 35
Y445
Q
Q
A
I
R
E
K
Y
K
A
S
K
Y
L
C
Site 36
Y450
E
K
Y
K
A
S
K
Y
L
C
V
S
L
M
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation