PhosphoNET

           
Protein Info 
   
Short Name:  POU6F2
Full Name:  POU domain, class 6, transcription factor 2
Alias:  Retina-derived POU domain factor 1
Type: 
Mass (Da):  72409
Number AA:  683
UniProt ID:  P78424
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S12QVSKPLLSVRSEMNA
Site 2S30GEDKAATSDSELNEP
Site 3S32DKAATSDSELNEPLL
Site 4S47APVESNDSEDTPSKL
Site 5T50ESNDSEDTPSKLFGA
Site 6S52NDSEDTPSKLFGARG
Site 7S64ARGNPALSDPGTPDQ
Site 8T68PALSDPGTPDQHQAS
Site 9S75TPDQHQASQTHPPFP
Site 10T77DQHQASQTHPPFPVG
Site 11S166QNLQATSSLNSQLQQ
Site 12S169QATSSLNSQLQQLQL
Site 13S192QQQQPPPSTNQHPQP
Site 14S205QPAPQAPSQSQQQPL
Site 15S207APQAPSQSQQQPLQP
Site 16T215QQQPLQPTPPQQPPP
Site 17S224PQQPPPASQQPPAPT
Site 18S232QQPPAPTSQLQQAPQ
Site 19S249QHQPHSHSQNQNQPS
Site 20S256SQNQNQPSPTQQSSS
Site 21T258NQNQPSPTQQSSSPP
Site 22S261QPSPTQQSSSPPQKP
Site 23S262PSPTQQSSSPPQKPS
Site 24S263SPTQQSSSPPQKPSQ
Site 25S269SSPPQKPSQSPGHGL
Site 26S271PPQKPSQSPGHGLPS
Site 27S278SPGHGLPSPLTPPNP
Site 28T281HGLPSPLTPPNPLQL
Site 29S349MPNPGPSSQAASGTQ
Site 30S353GPSSQAASGTQGLQV
Site 31S396NTQGITLSPIKPGQQ
Site 32S408GQQLHQPSQTSVGQA
Site 33S411LHQPSQTSVGQAASQ
Site 34S427NLLHLAHSQASMSQS
Site 35S430HLAHSQASMSQSPVR
Site 36S432AHSQASMSQSPVRQA
Site 37S434SQASMSQSPVRQASS
Site 38S440QSPVRQASSSSSSSS
Site 39S441SPVRQASSSSSSSSS
Site 40S442PVRQASSSSSSSSSS
Site 41S443VRQASSSSSSSSSSS
Site 42S444RQASSSSSSSSSSSA
Site 43S445QASSSSSSSSSSSAL
Site 44S446ASSSSSSSSSSSALS
Site 45S447SSSSSSSSSSSALSV
Site 46S448SSSSSSSSSSALSVG
Site 47S449SSSSSSSSSALSVGQ
Site 48S450SSSSSSSSALSVGQL
Site 49S453SSSSSALSVGQLVSN
Site 50T463QLVSNPQTAAGEVDG
Site 51S489AFKIRRLSLGLTQTQ
Site 52T493RRLSLGLTQTQVGQA
Site 53S502TQVGQALSATEGPAY
Site 54T504VGQALSATEGPAYSQ
Site 55Y509SATEGPAYSQSAICR
Site 56S510ATEGPAYSQSAICRH
Site 57S512EGPAYSQSAICRHTI
Site 58T518QSAICRHTILRSHFF
Site 59S538QENTIASSLTAKLNP
Site 60Y549KLNPGLLYPARFEKL
Site 61T559RFEKLDITPKSAQKI
Site 62S562KLDITPKSAQKIKPV
Site 63T589RAGMQNLTEFIGSEP
Site 64S594NLTEFIGSEPSKKRK
Site 65S597EFIGSEPSKKRKRRT
Site 66T604SKKRKRRTSFTPQAL
Site 67S605KKRKRRTSFTPQALE
Site 68T607RKRRTSFTPQALEIL
Site 69Y638EIAEKLNYDREVVRV
Site 70T668LKQHEPATAVPLEPL
Site 71T676AVPLEPLTDSLEENS
Site 72S678PLEPLTDSLEENS__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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