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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SRPX
Full Name:
Sushi repeat-containing protein SRPX
Alias:
Type:
Mass (Da):
51572
Number AA:
464
UniProt ID:
P78539
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S28
L
L
L
R
V
P
P
S
R
S
F
P
G
S
G
Site 2
S30
L
R
V
P
P
S
R
S
F
P
G
S
G
D
S
Site 3
S34
P
S
R
S
F
P
G
S
G
D
S
P
L
E
D
Site 4
S37
S
F
P
G
S
G
D
S
P
L
E
D
D
E
V
Site 5
Y46
L
E
D
D
E
V
G
Y
S
H
P
R
Y
K
D
Site 6
S47
E
D
D
E
V
G
Y
S
H
P
R
Y
K
D
T
Site 7
Y51
V
G
Y
S
H
P
R
Y
K
D
T
P
W
C
S
Site 8
T54
S
H
P
R
Y
K
D
T
P
W
C
S
P
I
K
Site 9
Y64
C
S
P
I
K
V
K
Y
G
D
V
Y
C
R
A
Site 10
Y68
K
V
K
Y
G
D
V
Y
C
R
A
P
Q
G
G
Site 11
Y77
R
A
P
Q
G
G
Y
Y
K
T
A
L
G
T
R
Site 12
T79
P
Q
G
G
Y
Y
K
T
A
L
G
T
R
C
D
Site 13
Y93
D
I
R
C
Q
K
G
Y
E
L
H
G
S
S
L
Site 14
S98
K
G
Y
E
L
H
G
S
S
L
L
I
C
Q
S
Site 15
S99
G
Y
E
L
H
G
S
S
L
L
I
C
Q
S
N
Site 16
S105
S
S
L
L
I
C
Q
S
N
K
R
W
S
D
K
Site 17
T122
C
K
Q
K
R
C
P
T
L
A
M
P
A
N
G
Site 18
Y138
F
K
C
V
D
G
A
Y
F
N
S
R
C
E
Y
Site 19
Y145
Y
F
N
S
R
C
E
Y
Y
C
S
P
G
Y
T
Site 20
Y146
F
N
S
R
C
E
Y
Y
C
S
P
G
Y
T
L
Site 21
S148
S
R
C
E
Y
Y
C
S
P
G
Y
T
L
K
G
Site 22
Y151
E
Y
Y
C
S
P
G
Y
T
L
K
G
E
R
T
Site 23
T152
Y
Y
C
S
P
G
Y
T
L
K
G
E
R
T
V
Site 24
T158
Y
T
L
K
G
E
R
T
V
T
C
M
D
N
K
Site 25
T160
L
K
G
E
R
T
V
T
C
M
D
N
K
A
W
Site 26
S173
A
W
S
G
R
P
A
S
C
V
D
M
E
P
P
Site 27
S186
P
P
R
I
K
C
P
S
V
K
E
R
I
A
E
Site 28
T198
I
A
E
P
N
K
L
T
V
R
V
S
W
E
T
Site 29
S202
N
K
L
T
V
R
V
S
W
E
T
P
E
G
R
Site 30
T205
T
V
R
V
S
W
E
T
P
E
G
R
D
T
A
Site 31
T211
E
T
P
E
G
R
D
T
A
D
G
I
L
T
D
Site 32
S228
L
K
G
L
P
P
G
S
N
F
P
E
G
D
H
Site 33
Y239
E
G
D
H
K
I
Q
Y
T
V
Y
D
R
A
E
Site 34
T240
G
D
H
K
I
Q
Y
T
V
Y
D
R
A
E
N
Site 35
Y242
H
K
I
Q
Y
T
V
Y
D
R
A
E
N
K
G
Site 36
Y272
L
N
A
P
E
N
G
Y
M
K
C
S
S
D
G
Site 37
Y282
C
S
S
D
G
D
N
Y
G
A
T
C
E
F
S
Site 38
Y294
E
F
S
C
I
G
G
Y
E
L
Q
G
S
P
A
Site 39
S299
G
G
Y
E
L
Q
G
S
P
A
R
V
C
Q
S
Site 40
T313
S
N
L
A
W
S
G
T
E
P
T
C
A
A
M
Site 41
S346
K
R
R
L
L
I
V
S
T
P
T
A
R
N
L
Site 42
Y429
H
G
M
D
K
E
R
Y
V
S
L
V
M
P
V
Site 43
T444
A
L
F
N
L
I
D
T
F
P
L
R
K
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation