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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ADARB1
Full Name:
Double-stranded RNA-specific editase 1
Alias:
dsRNA adenosine deaminase
Type:
Mass (Da):
80763
Number AA:
741
UniProt ID:
P78563
International Prot ID:
IPI00020368
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0044464
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0004000
GO:0003726
PhosphoSite+
KinaseNET
Biological Process:
GO:0006396
GO:0016553
GO:0006397
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
I
E
D
E
E
N
M
S
S
S
S
T
D
V
K
Site 2
S11
E
D
E
E
N
M
S
S
S
S
T
D
V
K
E
Site 3
S13
E
E
N
M
S
S
S
S
T
D
V
K
E
N
R
Site 4
T14
E
N
M
S
S
S
S
T
D
V
K
E
N
R
N
Site 5
S26
N
R
N
L
D
N
V
S
P
K
D
G
S
T
P
Site 6
S31
N
V
S
P
K
D
G
S
T
P
G
P
G
E
G
Site 7
T32
V
S
P
K
D
G
S
T
P
G
P
G
E
G
S
Site 8
S39
T
P
G
P
G
E
G
S
Q
L
S
N
G
G
G
Site 9
S42
P
G
E
G
S
Q
L
S
N
G
G
G
G
G
P
Site 10
S59
K
R
P
L
E
E
G
S
N
G
H
S
K
Y
R
Site 11
S63
E
E
G
S
N
G
H
S
K
Y
R
L
K
K
R
Site 12
Y65
G
S
N
G
H
S
K
Y
R
L
K
K
R
R
K
Site 13
T73
R
L
K
K
R
R
K
T
P
G
P
V
L
P
K
Site 14
Y95
E
I
K
P
G
L
Q
Y
T
L
L
S
Q
T
G
Site 15
T96
I
K
P
G
L
Q
Y
T
L
L
S
Q
T
G
P
Site 16
S99
G
L
Q
Y
T
L
L
S
Q
T
G
P
V
H
A
Site 17
S123
N
G
Q
V
F
E
G
S
G
P
T
K
K
K
A
Site 18
S141
A
A
E
K
A
L
R
S
F
V
Q
F
P
N
A
Site 19
S167
S
V
N
T
D
F
T
S
D
Q
A
D
F
P
D
Site 20
T175
D
Q
A
D
F
P
D
T
L
F
N
G
F
E
T
Site 21
T182
T
L
F
N
G
F
E
T
P
D
K
A
E
P
P
Site 22
Y191
D
K
A
E
P
P
F
Y
V
G
S
N
G
D
D
Site 23
S194
E
P
P
F
Y
V
G
S
N
G
D
D
S
F
S
Site 24
S199
V
G
S
N
G
D
D
S
F
S
S
S
G
D
L
Site 25
S201
S
N
G
D
D
S
F
S
S
S
G
D
L
S
L
Site 26
S202
N
G
D
D
S
F
S
S
S
G
D
L
S
L
S
Site 27
S203
G
D
D
S
F
S
S
S
G
D
L
S
L
S
A
Site 28
S207
F
S
S
S
G
D
L
S
L
S
A
S
P
V
P
Site 29
S209
S
S
G
D
L
S
L
S
A
S
P
V
P
A
S
Site 30
S211
G
D
L
S
L
S
A
S
P
V
P
A
S
L
A
Site 31
S232
L
P
P
F
P
P
P
S
G
K
N
P
V
M
I
Site 32
Y249
E
L
R
P
G
L
K
Y
D
F
L
S
E
S
G
Site 33
S253
G
L
K
Y
D
F
L
S
E
S
G
E
S
H
A
Site 34
S255
K
Y
D
F
L
S
E
S
G
E
S
H
A
K
S
Site 35
S258
F
L
S
E
S
G
E
S
H
A
K
S
F
V
M
Site 36
S277
D
G
Q
F
F
E
G
S
G
R
N
K
K
L
A
Site 37
T304
F
N
L
H
L
D
Q
T
P
S
R
Q
P
I
P
Site 38
S306
L
H
L
D
Q
T
P
S
R
Q
P
I
P
S
E
Site 39
S312
P
S
R
Q
P
I
P
S
E
G
L
Q
L
H
L
Site 40
T339
L
G
K
F
G
D
L
T
D
N
F
S
S
P
H
Site 41
S343
G
D
L
T
D
N
F
S
S
P
H
A
R
R
K
Site 42
S344
D
L
T
D
N
F
S
S
P
H
A
R
R
K
V
Site 43
S370
V
K
D
A
K
V
I
S
V
S
T
G
T
K
C
Site 44
T375
V
I
S
V
S
T
G
T
K
C
I
N
G
E
Y
Site 45
Y382
T
K
C
I
N
G
E
Y
M
S
D
R
G
L
A
Site 46
S384
C
I
N
G
E
Y
M
S
D
R
G
L
A
L
N
Site 47
S399
D
C
H
A
E
I
I
S
R
R
S
L
L
R
F
Site 48
Y414
L
Y
T
Q
L
E
L
Y
L
N
N
K
D
D
Q
Site 49
S424
N
K
D
D
Q
K
R
S
I
F
Q
K
S
E
R
Site 50
S429
K
R
S
I
F
Q
K
S
E
R
G
G
F
R
L
Site 51
Y445
E
N
V
Q
F
H
L
Y
I
S
T
S
P
C
G
Site 52
S458
C
G
D
A
R
I
F
S
P
H
E
P
I
L
E
Site 53
S469
P
I
L
E
G
S
R
S
Y
T
Q
A
G
V
Q
Site 54
Y470
I
L
E
G
S
R
S
Y
T
Q
A
G
V
Q
W
Site 55
T471
L
E
G
S
R
S
Y
T
Q
A
G
V
Q
W
C
Site 56
S492
P
R
P
P
G
L
L
S
D
P
S
T
S
T
F
Site 57
S495
P
G
L
L
S
D
P
S
T
S
T
F
Q
G
A
Site 58
T496
G
L
L
S
D
P
S
T
S
T
F
Q
G
A
G
Site 59
T498
L
S
D
P
S
T
S
T
F
Q
G
A
G
T
T
Site 60
T504
S
T
F
Q
G
A
G
T
T
E
P
A
D
R
H
Site 61
T522
K
A
R
G
Q
L
R
T
K
I
E
S
G
E
G
Site 62
S526
Q
L
R
T
K
I
E
S
G
E
G
T
I
P
V
Site 63
T530
K
I
E
S
G
E
G
T
I
P
V
R
S
N
A
Site 64
T553
L
Q
G
E
R
L
L
T
M
S
C
S
D
K
I
Site 65
S555
G
E
R
L
L
T
M
S
C
S
D
K
I
A
R
Site 66
S557
R
L
L
T
M
S
C
S
D
K
I
A
R
W
N
Site 67
Y581
S
I
F
V
E
P
I
Y
F
S
S
I
I
L
G
Site 68
S583
F
V
E
P
I
Y
F
S
S
I
I
L
G
S
L
Site 69
Y591
S
I
I
L
G
S
L
Y
H
G
D
H
L
S
R
Site 70
Y601
D
H
L
S
R
A
M
Y
Q
R
I
S
N
I
E
Site 71
S605
R
A
M
Y
Q
R
I
S
N
I
E
D
L
P
P
Site 72
T615
E
D
L
P
P
L
Y
T
L
N
K
P
L
L
S
Site 73
S622
T
L
N
K
P
L
L
S
G
I
S
N
A
E
A
Site 74
S639
P
G
K
A
P
N
F
S
V
N
W
T
V
G
D
Site 75
T643
P
N
F
S
V
N
W
T
V
G
D
S
A
I
E
Site 76
S665
K
D
E
L
G
R
A
S
R
L
C
K
H
A
L
Site 77
S685
R
V
H
G
K
V
P
S
H
L
L
R
S
K
I
Site 78
S690
V
P
S
H
L
L
R
S
K
I
T
K
P
N
V
Site 79
Y698
K
I
T
K
P
N
V
Y
H
E
S
K
L
A
A
Site 80
Y708
S
K
L
A
A
K
E
Y
Q
A
A
K
A
R
L
Site 81
T740
E
Q
D
Q
F
S
L
T
P
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation