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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NUCB2
Full Name:
Nucleobindin-2
Alias:
DNA-binding NEFA; DNA-binding protein NEFA; Gastric cancer antigen Zg4; NEFA; Nucb2 splice variant
Type:
Vesicle protein. Calcium binding protein. Nucleobindin family.
Mass (Da):
50196
Number AA:
420
UniProt ID:
P80303
International Prot ID:
IPI00009123
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005793
GO:0005829
GO:0005615
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T32
V
P
I
D
I
D
K
T
K
V
Q
N
I
H
P
Site 2
T50
A
K
I
E
P
P
D
T
G
L
Y
Y
D
E
Y
Site 3
Y53
E
P
P
D
T
G
L
Y
Y
D
E
Y
L
K
Q
Site 4
Y54
P
P
D
T
G
L
Y
Y
D
E
Y
L
K
Q
V
Site 5
Y57
T
G
L
Y
Y
D
E
Y
L
K
Q
V
I
D
V
Site 6
T67
Q
V
I
D
V
L
E
T
D
K
H
F
R
E
K
Site 7
S85
A
D
I
E
E
I
K
S
G
R
L
S
K
E
L
Site 8
S89
E
I
K
S
G
R
L
S
K
E
L
D
L
V
S
Site 9
S96
S
K
E
L
D
L
V
S
H
H
V
R
T
K
L
Site 10
S124
L
I
K
A
K
L
D
S
L
Q
D
I
G
M
D
Site 11
Y169
A
T
S
D
L
E
H
Y
D
K
T
R
H
E
E
Site 12
T172
D
L
E
H
Y
D
K
T
R
H
E
E
F
K
K
Site 13
Y180
R
H
E
E
F
K
K
Y
E
M
M
K
E
H
E
Site 14
Y191
K
E
H
E
R
R
E
Y
L
K
T
L
N
E
E
Site 15
T194
E
R
R
E
Y
L
K
T
L
N
E
E
K
R
K
Site 16
S205
E
K
R
K
E
E
E
S
K
F
E
E
M
K
K
Site 17
S225
P
K
V
N
H
P
G
S
K
D
Q
L
K
E
V
Site 18
T248
P
N
D
F
D
P
K
T
F
F
K
L
H
D
V
Site 19
S257
F
K
L
H
D
V
N
S
D
G
F
L
D
E
Q
Site 20
T271
Q
E
L
E
A
L
F
T
K
E
L
E
K
V
Y
Site 21
S303
R
M
R
E
H
V
M
S
E
V
D
T
N
K
D
Site 22
T307
H
V
M
S
E
V
D
T
N
K
D
R
L
V
T
Site 23
T314
T
N
K
D
R
L
V
T
L
E
E
F
L
K
A
Site 24
S332
K
E
F
L
E
P
D
S
W
E
T
L
D
Q
Q
Site 25
Y350
T
E
E
E
L
K
E
Y
E
N
I
I
A
L
Q
Site 26
S408
L
Q
Q
G
I
P
P
S
G
P
A
G
E
L
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation