PhosphoNET

           
Protein Info 
   
Short Name:  HTRA3
Full Name:  Probable serine protease HTRA3
Alias:  EC 3.4.21.-; High-temperature requirement factor A3; HtrA serine peptidase 3; Pregnancy-related serine protease; PRSP; Serine protease HTRA3; Tasp
Type:  Protease
Mass (Da):  48608
Number AA:  453
UniProt ID:  P83110
International Prot ID:  Isoform1 - IPI00027862
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005576     Uniprot OncoNet
Molecular Function:  GO:0005520  GO:0004252   PhosphoSite+ KinaseNET
Biological Process:  GO:0006508  GO:0001558   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S36CDVSRCPSPRCPGGY
Site 2Y43SPRCPGGYVPDLCNC
Site 3S68PCGGPLDSPCGESLE
Site 4Y97CGTDGHTYANVCALQ
Site 5S114SRRALQLSGTPVRQL
Site 6T116RALQLSGTPVRQLQK
Site 7S134PLGLHQLSSPRYKFN
Site 8S135LGLHQLSSPRYKFNF
Site 9Y138HQLSSPRYKFNFIAD
Site 10S174GRNVPLSSGSGFIMS
Site 11S197AHVVSSNSAAPGRQQ
Site 12S214VQLQNGDSYEATIKD
Site 13Y215QLQNGDSYEATIKDI
Site 14T218NGDSYEATIKDIDKK
Site 15S226IKDIDKKSDIATIKI
Site 16T230DKKSDIATIKIHPKK
Site 17S289RELGLRDSDMDYIQT
Site 18Y293LRDSDMDYIQTDAII
Site 19Y302QTDAIINYGNSGGPL
Site 20S334GISFAIPSDRITRFL
Site 21T338AIPSDRITRFLTEFQ
Site 22T342DRITRFLTEFQDKQI
Site 23T363FIGIRMRTITPSLVD
Site 24S367RMRTITPSLVDELKA
Site 25S375LVDELKASNPDFPEV
Site 26Y387PEVSSGIYVQEVAPN
Site 27S395VQEVAPNSPSQRGGI
Site 28S397EVAPNSPSQRGGIQD
Site 29S419NGRPLVDSSELQEAV
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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