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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HPCA
Full Name:
Neuron-specific calcium-binding protein hippocalcin
Alias:
BDR2; Calcium-binding protein BDR-2; Hippocalcin
Type:
Actin binding protein
Mass (Da):
22427
Number AA:
193
UniProt ID:
P84074
International Prot ID:
IPI00219103
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003779
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T20
L
Q
D
L
R
E
N
T
E
F
S
E
L
E
L
Site 2
S23
L
R
E
N
T
E
F
S
E
L
E
L
Q
E
W
Site 3
Y52
V
D
E
F
K
K
I
Y
A
N
F
F
P
Y
G
Site 4
Y58
I
Y
A
N
F
F
P
Y
G
D
A
S
K
F
A
Site 5
T71
F
A
E
H
V
F
R
T
F
D
T
N
S
D
G
Site 6
T74
H
V
F
R
T
F
D
T
N
S
D
G
T
I
D
Site 7
S76
F
R
T
F
D
T
N
S
D
G
T
I
D
F
R
Site 8
Y108
L
M
W
A
F
S
M
Y
D
L
D
G
N
G
Y
Site 9
Y115
Y
D
L
D
G
N
G
Y
I
S
R
E
E
M
L
Site 10
S117
L
D
G
N
G
Y
I
S
R
E
E
M
L
E
I
Site 11
Y129
L
E
I
V
Q
A
I
Y
K
M
V
S
S
V
M
Site 12
S134
A
I
Y
K
M
V
S
S
V
M
K
M
P
E
D
Site 13
S143
M
K
M
P
E
D
E
S
T
P
E
K
R
T
E
Site 14
T144
K
M
P
E
D
E
S
T
P
E
K
R
T
E
K
Site 15
T158
K
I
F
R
Q
M
D
T
N
N
D
G
K
L
S
Site 16
S165
T
N
N
D
G
K
L
S
L
E
E
F
I
R
G
Site 17
S175
E
F
I
R
G
A
K
S
D
P
S
I
V
R
L
Site 18
S178
R
G
A
K
S
D
P
S
I
V
R
L
L
Q
C
Site 19
S188
R
L
L
Q
C
D
P
S
S
A
S
Q
F
_
_
Site 20
S189
L
L
Q
C
D
P
S
S
A
S
Q
F
_
_
_
Site 21
S191
Q
C
D
P
S
S
A
S
Q
F
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation