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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FOXK1
Full Name:
Forkhead box protein K1
Alias:
MNF; Myocyte nuclear factor
Type:
Transcription protein
Mass (Da):
75457
Number AA:
733
UniProt ID:
P85037
International Prot ID:
IPI00465123
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0043565
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0030154
GO:0007517
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S74
G
A
G
S
S
G
G
S
S
G
V
S
G
D
S
Site 2
S75
A
G
S
S
G
G
S
S
G
V
S
G
D
S
A
Site 3
S78
S
G
G
S
S
G
V
S
G
D
S
A
V
A
G
Site 4
S101
A
A
A
S
V
R
Q
S
P
G
P
A
L
A
R
Site 5
S122
E
F
L
M
R
Q
P
S
V
T
I
G
R
N
S
Site 6
T124
L
M
R
Q
P
S
V
T
I
G
R
N
S
S
Q
Site 7
S129
S
V
T
I
G
R
N
S
S
Q
G
S
V
D
L
Site 8
S130
V
T
I
G
R
N
S
S
Q
G
S
V
D
L
S
Site 9
S133
G
R
N
S
S
Q
G
S
V
D
L
S
M
G
L
Site 10
S141
V
D
L
S
M
G
L
S
S
F
I
S
R
R
H
Site 11
S142
D
L
S
M
G
L
S
S
F
I
S
R
R
H
L
Site 12
S145
M
G
L
S
S
F
I
S
R
R
H
L
Q
L
S
Site 13
S152
S
R
R
H
L
Q
L
S
F
Q
E
P
H
F
Y
Site 14
Y159
S
F
Q
E
P
H
F
Y
L
R
C
L
G
K
N
Site 15
T189
L
Q
L
P
K
Q
C
T
F
R
F
P
S
T
A
Site 16
Y205
K
I
Q
F
T
S
L
Y
H
K
E
E
A
P
A
Site 17
S213
H
K
E
E
A
P
A
S
P
L
R
P
L
Y
P
Site 18
Y219
A
S
P
L
R
P
L
Y
P
Q
I
S
P
L
K
Site 19
S223
R
P
L
Y
P
Q
I
S
P
L
K
I
H
I
P
Site 20
S236
I
P
E
P
D
L
R
S
M
V
S
P
V
P
S
Site 21
S239
P
D
L
R
S
M
V
S
P
V
P
S
P
T
G
Site 22
S243
S
M
V
S
P
V
P
S
P
T
G
T
I
S
V
Site 23
T245
V
S
P
V
P
S
P
T
G
T
I
S
V
P
N
Site 24
T247
P
V
P
S
P
T
G
T
I
S
V
P
N
S
C
Site 25
S249
P
S
P
T
G
T
I
S
V
P
N
S
C
P
A
Site 26
S253
G
T
I
S
V
P
N
S
C
P
A
S
P
R
G
Site 27
S257
V
P
N
S
C
P
A
S
P
R
G
A
G
S
S
Site 28
S263
A
S
P
R
G
A
G
S
S
S
Y
R
F
V
Q
Site 29
S264
S
P
R
G
A
G
S
S
S
Y
R
F
V
Q
N
Site 30
S265
P
R
G
A
G
S
S
S
Y
R
F
V
Q
N
V
Site 31
Y266
R
G
A
G
S
S
S
Y
R
F
V
Q
N
V
T
Site 32
T273
Y
R
F
V
Q
N
V
T
S
D
L
Q
L
A
A
Site 33
S288
E
F
A
A
K
A
A
S
E
Q
Q
A
D
T
S
Site 34
T294
A
S
E
Q
Q
A
D
T
S
G
G
D
S
P
K
Site 35
S295
S
E
Q
Q
A
D
T
S
G
G
D
S
P
K
D
Site 36
S299
A
D
T
S
G
G
D
S
P
K
D
E
S
K
P
Site 37
S304
G
D
S
P
K
D
E
S
K
P
P
F
S
Y
A
Site 38
S309
D
E
S
K
P
P
F
S
Y
A
Q
L
I
V
Q
Site 39
Y310
E
S
K
P
P
F
S
Y
A
Q
L
I
V
Q
A
Site 40
T327
S
A
Q
D
R
Q
L
T
L
S
G
I
Y
A
H
Site 41
S329
Q
D
R
Q
L
T
L
S
G
I
Y
A
H
I
T
Site 42
Y339
Y
A
H
I
T
K
H
Y
P
Y
Y
R
T
A
D
Site 43
Y341
H
I
T
K
H
Y
P
Y
Y
R
T
A
D
K
G
Site 44
Y342
I
T
K
H
Y
P
Y
Y
R
T
A
D
K
G
W
Site 45
S352
A
D
K
G
W
Q
N
S
I
R
H
N
L
S
L
Site 46
S358
N
S
I
R
H
N
L
S
L
N
R
Y
F
I
K
Site 47
Y362
H
N
L
S
L
N
R
Y
F
I
K
V
P
R
S
Site 48
S369
Y
F
I
K
V
P
R
S
Q
E
E
P
G
K
G
Site 49
S377
Q
E
E
P
G
K
G
S
F
W
R
I
D
P
A
Site 50
S385
F
W
R
I
D
P
A
S
E
A
K
L
V
E
Q
Site 51
S403
K
R
R
Q
R
G
V
S
C
F
R
T
P
F
G
Site 52
T407
R
G
V
S
C
F
R
T
P
F
G
P
L
S
S
Site 53
S413
R
T
P
F
G
P
L
S
S
R
S
A
P
A
S
Site 54
S414
T
P
F
G
P
L
S
S
R
S
A
P
A
S
P
Site 55
S416
F
G
P
L
S
S
R
S
A
P
A
S
P
T
H
Site 56
S420
S
S
R
S
A
P
A
S
P
T
H
P
G
L
M
Site 57
T422
R
S
A
P
A
S
P
T
H
P
G
L
M
S
P
Site 58
S428
P
T
H
P
G
L
M
S
P
R
S
G
G
L
Q
Site 59
S431
P
G
L
M
S
P
R
S
G
G
L
Q
T
P
E
Site 60
T436
P
R
S
G
G
L
Q
T
P
E
C
L
S
R
E
Site 61
S441
L
Q
T
P
E
C
L
S
R
E
G
S
P
I
P
Site 62
S445
E
C
L
S
R
E
G
S
P
I
P
H
D
P
E
Site 63
S455
P
H
D
P
E
F
G
S
K
L
A
S
V
P
E
Site 64
S459
E
F
G
S
K
L
A
S
V
P
E
Y
R
Y
S
Site 65
Y463
K
L
A
S
V
P
E
Y
R
Y
S
Q
S
A
P
Site 66
Y465
A
S
V
P
E
Y
R
Y
S
Q
S
A
P
G
S
Site 67
S466
S
V
P
E
Y
R
Y
S
Q
S
A
P
G
S
P
Site 68
S468
P
E
Y
R
Y
S
Q
S
A
P
G
S
P
V
S
Site 69
S472
Y
S
Q
S
A
P
G
S
P
V
S
A
Q
P
V
Site 70
S488
M
A
V
P
P
R
P
S
S
L
V
A
K
P
V
Site 71
S505
M
P
A
S
I
V
T
S
Q
Q
P
A
G
H
A
Site 72
T523
V
Q
Q
A
P
T
V
T
M
V
R
V
V
T
T
Site 73
S531
M
V
R
V
V
T
T
S
A
N
S
A
N
G
Y
Site 74
Y538
S
A
N
S
A
N
G
Y
I
L
T
S
Q
G
A
Site 75
S542
A
N
G
Y
I
L
T
S
Q
G
A
A
G
G
S
Site 76
S549
S
Q
G
A
A
G
G
S
H
D
A
A
G
A
A
Site 77
S562
A
A
V
L
D
L
G
S
E
A
R
G
L
E
E
Site 78
T572
R
G
L
E
E
K
P
T
I
A
F
A
T
I
P
Site 79
T611
L
Q
P
A
T
P
V
T
L
G
Q
H
H
L
P
Site 80
T623
H
L
P
V
R
A
V
T
Q
N
G
K
H
A
V
Site 81
S634
K
H
A
V
P
T
N
S
L
A
G
N
A
Y
A
Site 82
Y640
N
S
L
A
G
N
A
Y
A
L
T
S
P
L
Q
Site 83
S644
G
N
A
Y
A
L
T
S
P
L
Q
L
L
A
T
Site 84
T651
S
P
L
Q
L
L
A
T
Q
A
S
S
S
A
P
Site 85
T689
T
T
P
A
T
A
T
T
A
S
A
S
A
S
S
Site 86
S691
P
A
T
A
T
T
A
S
A
S
A
S
S
T
G
Site 87
S693
T
A
T
T
A
S
A
S
A
S
S
T
G
E
P
Site 88
S695
T
T
A
S
A
S
A
S
S
T
G
E
P
E
V
Site 89
T697
A
S
A
S
A
S
S
T
G
E
P
E
V
K
R
Site 90
S705
G
E
P
E
V
K
R
S
R
V
E
E
P
S
G
Site 91
S711
R
S
R
V
E
E
P
S
G
A
V
T
T
P
A
Site 92
T716
E
P
S
G
A
V
T
T
P
A
G
V
I
A
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation