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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PRR5
Full Name:
Proline-rich protein 5
Alias:
PP610; Proline-rich protein 5
Type:
Mass (Da):
42753
Number AA:
388
UniProt ID:
P85299
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0007049
GO:0045786
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
L
R
R
L
K
F
M
S
S
P
S
L
S
D
L
Site 2
S12
R
R
L
K
F
M
S
S
P
S
L
S
D
L
G
Site 3
S14
L
K
F
M
S
S
P
S
L
S
D
L
G
K
R
Site 4
S16
F
M
S
S
P
S
L
S
D
L
G
K
R
E
P
Site 5
T32
A
A
A
D
E
R
G
T
Q
Q
R
R
A
C
A
Site 6
S66
L
P
D
Q
E
L
F
S
L
N
E
G
V
R
Q
Site 7
Y106
L
R
D
K
I
R
F
Y
E
G
Q
K
L
L
D
Site 8
S114
E
G
Q
K
L
L
D
S
L
A
E
T
W
D
F
Site 9
Y135
P
M
L
Q
A
I
F
Y
P
V
Q
G
K
E
P
Site 10
S143
P
V
Q
G
K
E
P
S
V
R
Q
L
A
L
L
Site 11
T157
L
H
F
R
N
A
I
T
L
S
V
K
L
E
D
Site 12
T194
V
H
E
S
R
G
V
T
E
D
Y
L
R
L
E
Site 13
Y197
S
R
G
V
T
E
D
Y
L
R
L
E
T
L
V
Site 14
T202
E
D
Y
L
R
L
E
T
L
V
Q
K
V
V
S
Site 15
Y215
V
S
P
Y
L
G
T
Y
G
L
H
S
S
E
G
Site 16
S219
L
G
T
Y
G
L
H
S
S
E
G
P
F
T
H
Site 17
S220
G
T
Y
G
L
H
S
S
E
G
P
F
T
H
S
Site 18
T225
H
S
S
E
G
P
F
T
H
S
C
I
L
E
K
Site 19
S238
E
K
R
L
L
R
R
S
R
S
G
D
V
L
A
Site 20
S240
R
L
L
R
R
S
R
S
G
D
V
L
A
K
N
Site 21
S252
A
K
N
P
V
V
R
S
K
S
Y
N
T
P
L
Site 22
S254
N
P
V
V
R
S
K
S
Y
N
T
P
L
L
N
Site 23
Y255
P
V
V
R
S
K
S
Y
N
T
P
L
L
N
P
Site 24
T257
V
R
S
K
S
Y
N
T
P
L
L
N
P
V
Q
Site 25
S277
G
A
A
A
G
G
T
S
I
R
R
H
S
V
S
Site 26
S282
G
T
S
I
R
R
H
S
V
S
E
M
T
S
C
Site 27
S284
S
I
R
R
H
S
V
S
E
M
T
S
C
P
E
Site 28
T287
R
H
S
V
S
E
M
T
S
C
P
E
P
Q
G
Site 29
S288
H
S
V
S
E
M
T
S
C
P
E
P
Q
G
F
Site 30
S296
C
P
E
P
Q
G
F
S
D
P
P
G
Q
G
P
Site 31
T306
P
G
Q
G
P
T
G
T
F
R
S
S
P
A
P
Site 32
S309
G
P
T
G
T
F
R
S
S
P
A
P
H
S
G
Site 33
S310
P
T
G
T
F
R
S
S
P
A
P
H
S
G
P
Site 34
S315
R
S
S
P
A
P
H
S
G
P
C
P
S
R
L
Site 35
S320
P
H
S
G
P
C
P
S
R
L
Y
P
T
T
Q
Site 36
Y323
G
P
C
P
S
R
L
Y
P
T
T
Q
P
P
E
Site 37
T326
P
S
R
L
Y
P
T
T
Q
P
P
E
Q
G
L
Site 38
T336
P
E
Q
G
L
D
P
T
R
S
S
L
P
R
S
Site 39
S338
Q
G
L
D
P
T
R
S
S
L
P
R
S
S
P
Site 40
S339
G
L
D
P
T
R
S
S
L
P
R
S
S
P
E
Site 41
S343
T
R
S
S
L
P
R
S
S
P
E
N
L
V
D
Site 42
S344
R
S
S
L
P
R
S
S
P
E
N
L
V
D
Q
Site 43
S355
L
V
D
Q
I
L
E
S
V
D
S
D
S
E
G
Site 44
S360
L
E
S
V
D
S
D
S
E
G
I
F
I
D
F
Site 45
S373
D
F
G
R
G
R
G
S
G
M
S
D
L
E
G
Site 46
S376
R
G
R
G
S
G
M
S
D
L
E
G
S
G
G
Site 47
S381
G
M
S
D
L
E
G
S
G
G
R
Q
S
V
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation