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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FBLN2
Full Name:
Fibulin-2
Alias:
fbln2; fibulin 2; fibulin-2
Type:
Mass (Da):
126540
Number AA:
UniProt ID:
P98095
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005578
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005201
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T34
A
A
P
R
Q
D
C
T
G
V
E
C
P
P
L
Site 2
Y70
C
A
C
E
G
Y
Q
Y
Y
D
C
L
Q
G
G
Site 3
Y71
A
C
E
G
Y
Q
Y
Y
D
C
L
Q
G
G
F
Site 4
S88
G
R
V
P
A
G
Q
S
Y
F
V
D
F
G
S
Site 5
Y89
R
V
P
A
G
Q
S
Y
F
V
D
F
G
S
T
Site 6
S95
S
Y
F
V
D
F
G
S
T
E
C
S
C
P
P
Site 7
S99
D
F
G
S
T
E
C
S
C
P
P
G
G
G
K
Site 8
T151
H
K
Y
A
A
G
H
T
V
H
L
P
P
C
R
Site 9
S182
P
G
C
H
G
N
F
S
D
A
E
E
G
D
P
Site 10
Y193
E
G
D
P
E
R
H
Y
E
D
P
Y
S
Y
D
Site 11
Y197
E
R
H
Y
E
D
P
Y
S
Y
D
Q
E
V
A
Site 12
S198
R
H
Y
E
D
P
Y
S
Y
D
Q
E
V
A
E
Site 13
S236
P
A
A
L
G
G
G
S
Q
P
L
S
T
I
Q
Site 14
S240
G
G
G
S
Q
P
L
S
T
I
Q
A
P
P
W
Site 15
T241
G
G
S
Q
P
L
S
T
I
Q
A
P
P
W
P
Site 16
T274
Q
A
K
A
R
R
V
T
E
D
S
E
E
E
E
Site 17
S277
A
R
R
V
T
E
D
S
E
E
E
E
E
E
E
Site 18
T293
E
R
E
E
M
A
V
T
E
Q
L
A
A
G
G
Site 19
T309
R
G
L
D
G
L
P
T
T
A
P
A
G
P
S
Site 20
T347
L
I
L
D
A
Q
A
T
S
R
S
T
G
P
E
Site 21
S348
I
L
D
A
Q
A
T
S
R
S
T
G
P
E
G
Site 22
S350
D
A
Q
A
T
S
R
S
T
G
P
E
G
V
T
Site 23
T351
A
Q
A
T
S
R
S
T
G
P
E
G
V
T
H
Site 24
T357
S
T
G
P
E
G
V
T
H
A
P
S
L
G
K
Site 25
S376
P
T
Q
A
V
P
G
S
P
R
D
P
V
K
P
Site 26
S384
P
R
D
P
V
K
P
S
P
H
N
I
L
S
T
Site 27
S390
P
S
P
H
N
I
L
S
T
S
L
P
D
A
A
Site 28
T391
S
P
H
N
I
L
S
T
S
L
P
D
A
A
W
Site 29
S415
K
P
Q
V
L
P
H
S
H
V
E
E
D
T
D
Site 30
T421
H
S
H
V
E
E
D
T
D
P
N
S
V
H
S
Site 31
S425
E
E
D
T
D
P
N
S
V
H
S
I
P
R
S
Site 32
S428
T
D
P
N
S
V
H
S
I
P
R
S
S
P
E
Site 33
S432
S
V
H
S
I
P
R
S
S
P
E
G
S
T
K
Site 34
S433
V
H
S
I
P
R
S
S
P
E
G
S
T
K
D
Site 35
S437
P
R
S
S
P
E
G
S
T
K
D
L
I
E
T
Site 36
S465
E
C
L
E
I
P
E
S
G
T
E
D
N
V
C
Site 37
S509
C
G
A
E
D
N
D
S
C
G
I
S
L
Y
K
Site 38
S534
R
V
R
A
E
G
Q
S
C
E
S
N
P
N
L
Site 39
S537
A
E
G
Q
S
C
E
S
N
P
N
L
G
Y
P
Site 40
Y543
E
S
N
P
N
L
G
Y
P
C
N
H
V
M
L
Site 41
S578
A
A
A
P
R
R
V
S
E
A
E
M
A
G
R
Site 42
S599
T
E
A
E
L
P
N
S
L
P
G
D
D
Q
D
Site 43
T643
S
L
Q
D
D
G
R
T
C
R
P
E
G
H
P
Site 44
S663
P
Q
E
P
A
L
K
S
E
F
S
Q
V
A
S
Site 45
S666
P
A
L
K
S
E
F
S
Q
V
A
S
N
T
I
Site 46
T682
L
P
L
P
Q
P
N
T
C
K
D
N
G
P
C
Site 47
T729
E
C
V
T
D
L
H
T
C
S
R
G
E
H
C
Site 48
Y746
T
L
G
S
F
H
C
Y
K
A
L
T
C
E
P
Site 49
Y755
A
L
T
C
E
P
G
Y
A
L
K
D
G
E
C
Site 50
S816
V
D
I
N
E
C
T
S
L
S
E
P
C
R
P
Site 51
S818
I
N
E
C
T
S
L
S
E
P
C
R
P
G
F
Site 52
S826
E
P
C
R
P
G
F
S
C
I
N
T
V
G
S
Site 53
T835
I
N
T
V
G
S
Y
T
C
Q
R
N
P
L
I
Site 54
Y847
P
L
I
C
A
R
G
Y
H
A
S
D
D
G
T
Site 55
S850
C
A
R
G
Y
H
A
S
D
D
G
T
K
C
V
Site 56
T916
P
G
R
L
C
Q
H
T
C
E
N
T
L
G
S
Site 57
S923
T
C
E
N
T
L
G
S
Y
R
C
S
C
A
S
Site 58
Y960
S
Q
E
C
A
N
I
Y
G
S
Y
Q
C
Y
C
Site 59
Y966
I
Y
G
S
Y
Q
C
Y
C
R
Q
G
Y
Q
L
Site 60
Y971
Q
C
Y
C
R
Q
G
Y
Q
L
A
E
D
G
H
Site 61
T979
Q
L
A
E
D
G
H
T
C
T
D
I
D
E
C
Site 62
T1015
A
C
P
E
Q
G
Y
T
M
T
A
N
G
R
S
Site 63
T1017
P
E
Q
G
Y
T
M
T
A
N
G
R
S
C
K
Site 64
Y1060
R
F
E
C
P
P
N
Y
V
Q
V
S
K
T
K
Site 65
T1066
N
Y
V
Q
V
S
K
T
K
C
E
R
T
T
C
Site 66
S1082
D
F
L
E
C
Q
N
S
P
A
R
I
T
H
Y
Site 67
T1087
Q
N
S
P
A
R
I
T
H
Y
Q
L
N
F
Q
Site 68
Y1089
S
P
A
R
I
T
H
Y
Q
L
N
F
Q
T
G
Site 69
Y1129
I
K
G
N
E
E
G
Y
F
G
T
R
R
L
N
Site 70
Y1138
G
T
R
R
L
N
A
Y
T
G
V
V
Y
L
Q
Site 71
T1139
T
R
R
L
N
A
Y
T
G
V
V
Y
L
Q
R
Site 72
S1167
M
K
L
W
R
Q
G
S
V
T
T
F
L
A
K
Site 73
T1169
L
W
R
Q
G
S
V
T
T
F
L
A
K
M
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation