PhosphoNET

           
Protein Info 
   
Short Name:  DGCR2
Full Name:  Integral membrane protein DGCR2/IDD
Alias:  DGS-C; DiGeorge syndrome critical region gene 2; DKFZp686I1730; IDD; integral membrane protein DGCR2; KIAA0163; LAN; SEZ-12
Type: 
Mass (Da):  60811
Number AA:  550
UniProt ID:  P98153
International Prot ID:  IPI00024272
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016021     Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0004872  GO:0005529 PhosphoSite+ KinaseNET
Biological Process:  GO:0007155  GO:0009887   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S295KGDDPCLSCTCHGGE
Site 2T297DDPCLSCTCHGGEPE
Site 3S339CLDPDGNSLFDSMAS
Site 4S343DGNSLFDSMASGMRL
Site 5S346SLFDSMASGMRLVVS
Site 6S381RRRERIESLIGANLH
Site 7Y401RRIPGFDYGPDGFGT
Site 8T408YGPDGFGTGLTPLHL
Site 9T411DGFGTGLTPLHLSDD
Site 10S416GLTPLHLSDDGEGGT
Site 11T423SDDGEGGTFHFHDPP
Site 12Y433FHDPPPPYTAYKYPD
Site 13T434HDPPPPYTAYKYPDI
Site 14Y436PPPPYTAYKYPDIGQ
Site 15Y438PPYTAYKYPDIGQPD
Site 16Y451PDDPPPPYEASIHPD
Site 17S454PPPPYEASIHPDSVF
Site 18S459EASIHPDSVFYDPAD
Site 19S485PAPGDGGSEGALLRR
Site 20T499RLEQPLPTAGASLAD
Site 21S503PLPTAGASLADLEDS
Site 22S510SLADLEDSADSSSAL
Site 23S513DLEDSADSSSALLVP
Site 24S514LEDSADSSSALLVPP
Site 25S515EDSADSSSALLVPPD
Site 26S528PDPAQSGSTPAAEAL
Site 27T529DPAQSGSTPAAEALP
Site 28S542LPGGGRHSRSSLNTV
Site 29S544GGGRHSRSSLNTVV_
Site 30S545GGRHSRSSLNTVV__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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