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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ATP2C1
Full Name:
Calcium-transporting ATPase type 2C member 1
Alias:
AT2C1; ATP2C1A; ATPase 2C1; ATP-dependent Ca(2+) pump; ATP-dependent Ca(2+) pump PMR1; EC 3.6.3.8; HHD; HUSSY-28; PMR1; PMR1L; SPCA1
Type:
Transporter, cations, Mg2+
Mass (Da):
100577
Number AA:
919
UniProt ID:
P98194
International Prot ID:
IPI00419957
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0000139
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0005509
GO:0005388
PhosphoSite+
KinaseNET
Biological Process:
GO:0006754
GO:0032468
GO:0032472
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S27
V
L
T
S
K
K
A
S
E
L
P
V
S
E
V
Site 2
Y75
D
E
P
L
W
K
K
Y
I
S
Q
F
K
N
P
Site 3
S124
A
F
V
Q
E
Y
R
S
E
K
S
L
E
E
L
Site 4
S127
Q
E
Y
R
S
E
K
S
L
E
E
L
S
K
L
Site 5
S132
E
K
S
L
E
E
L
S
K
L
V
P
P
E
C
Site 6
T150
R
E
G
K
L
E
H
T
L
A
R
D
L
V
P
Site 7
S186
V
D
L
S
I
D
E
S
S
L
T
G
E
T
T
Site 8
S187
D
L
S
I
D
E
S
S
L
T
G
E
T
T
P
Site 9
T189
S
I
D
E
S
S
L
T
G
E
T
T
P
C
S
Site 10
T193
S
S
L
T
G
E
T
T
P
C
S
K
V
T
A
Site 11
S196
T
G
E
T
T
P
C
S
K
V
T
A
P
Q
P
Site 12
S212
A
T
N
G
D
L
A
S
R
S
N
I
A
F
M
Site 13
S214
N
G
D
L
A
S
R
S
N
I
A
F
M
G
T
Site 14
T256
Q
A
E
E
A
P
K
T
P
L
Q
K
S
M
D
Site 15
S261
P
K
T
P
L
Q
K
S
M
D
L
L
G
K
Q
Site 16
T363
T
K
N
E
M
T
V
T
H
I
F
T
S
D
G
Site 17
T376
D
G
L
H
A
E
V
T
G
V
G
Y
N
Q
F
Site 18
T420
D
A
V
I
R
N
N
T
L
M
G
K
P
T
E
Site 19
T426
N
T
L
M
G
K
P
T
E
G
A
L
I
A
L
Site 20
Y446
L
D
G
L
Q
Q
D
Y
I
R
K
A
E
Y
P
Site 21
Y452
D
Y
I
R
K
A
E
Y
P
F
S
S
E
Q
K
Site 22
S455
R
K
A
E
Y
P
F
S
S
E
Q
K
W
M
A
Site 23
Y489
A
Y
E
Q
V
I
K
Y
C
T
T
Y
Q
S
K
Site 24
Y493
V
I
K
Y
C
T
T
Y
Q
S
K
G
Q
T
L
Site 25
T499
T
Y
Q
S
K
G
Q
T
L
T
L
T
Q
Q
Q
Site 26
T501
Q
S
K
G
Q
T
L
T
L
T
Q
Q
Q
R
D
Site 27
T503
K
G
Q
T
L
T
L
T
Q
Q
Q
R
D
V
Y
Site 28
Y510
T
Q
Q
Q
R
D
V
Y
Q
Q
E
K
A
R
M
Site 29
S519
Q
E
K
A
R
M
G
S
A
G
L
R
V
L
A
Site 30
Y587
I
A
S
R
L
G
L
Y
S
K
T
S
Q
S
V
Site 31
S588
A
S
R
L
G
L
Y
S
K
T
S
Q
S
V
S
Site 32
T590
R
L
G
L
Y
S
K
T
S
Q
S
V
S
G
E
Site 33
S591
L
G
L
Y
S
K
T
S
Q
S
V
S
G
E
E
Site 34
S593
L
Y
S
K
T
S
Q
S
V
S
G
E
E
I
D
Site 35
S595
S
K
T
S
Q
S
V
S
G
E
E
I
D
A
M
Site 36
Y618
V
P
K
V
A
V
F
Y
R
A
S
P
R
H
K
Site 37
S621
V
A
V
F
Y
R
A
S
P
R
H
K
M
K
I
Site 38
S631
H
K
M
K
I
I
K
S
L
Q
K
N
G
S
V
Site 39
S637
K
S
L
Q
K
N
G
S
V
V
A
M
T
G
D
Site 40
S687
D
D
F
Q
T
I
M
S
A
I
E
E
G
K
G
Site 41
S748
M
D
G
P
P
A
Q
S
L
G
V
E
P
V
D
Site 42
S769
P
P
R
N
W
K
D
S
I
L
T
K
N
L
I
Site 43
T804
E
L
R
D
N
V
I
T
P
R
D
T
T
M
T
Site 44
S825
F
D
M
F
N
A
L
S
S
R
S
Q
T
K
S
Site 45
S826
D
M
F
N
A
L
S
S
R
S
Q
T
K
S
V
Site 46
S828
F
N
A
L
S
S
R
S
Q
T
K
S
V
F
E
Site 47
T830
A
L
S
S
R
S
Q
T
K
S
V
F
E
I
G
Site 48
S832
S
S
R
S
Q
T
K
S
V
F
E
I
G
L
C
Site 49
T870
P
L
Q
K
V
F
Q
T
E
S
L
S
I
L
D
Site 50
S910
E
K
I
Q
K
H
V
S
S
T
S
S
S
F
L
Site 51
S911
K
I
Q
K
H
V
S
S
T
S
S
S
F
L
E
Site 52
S913
Q
K
H
V
S
S
T
S
S
S
F
L
E
V
_
Site 53
S914
K
H
V
S
S
T
S
S
S
F
L
E
V
_
_
Site 54
S915
H
V
S
S
T
S
S
S
F
L
E
V
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation