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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HOXA4
Full Name:
Homeobox protein Hox-A4
Alias:
Dfd-like; Homeobox A4; HOX1; Hox-1.4; HOX1D; HXA; HXA4
Type:
Transcription factor
Mass (Da):
34499
Number AA:
320
UniProt ID:
Q00056
International Prot ID:
IPI00020926
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0043565
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
M
S
S
F
L
I
N
S
N
Y
I
E
P
K
F
Site 2
Y12
S
F
L
I
N
S
N
Y
I
E
P
K
F
P
P
Site 3
Y23
K
F
P
P
F
E
E
Y
A
Q
H
S
G
S
G
Site 4
S29
E
Y
A
Q
H
S
G
S
G
G
A
D
G
G
P
Site 5
Y42
G
P
G
G
G
P
G
Y
Q
Q
P
P
A
P
P
Site 6
T50
Q
Q
P
P
A
P
P
T
Q
H
L
P
L
Q
Q
Site 7
T70
A
G
G
G
R
E
P
T
A
S
Y
Y
A
P
R
Site 8
S72
G
G
R
E
P
T
A
S
Y
Y
A
P
R
T
A
Site 9
Y73
G
R
E
P
T
A
S
Y
Y
A
P
R
T
A
R
Site 10
Y74
R
E
P
T
A
S
Y
Y
A
P
R
T
A
R
E
Site 11
T78
A
S
Y
Y
A
P
R
T
A
R
E
P
A
Y
P
Site 12
Y84
R
T
A
R
E
P
A
Y
P
A
A
A
L
Y
P
Site 13
T98
P
A
H
G
A
A
D
T
A
Y
P
Y
G
Y
R
Site 14
Y100
H
G
A
A
D
T
A
Y
P
Y
G
Y
R
G
G
Site 15
Y102
A
A
D
T
A
Y
P
Y
G
Y
R
G
G
A
S
Site 16
S109
Y
G
Y
R
G
G
A
S
P
G
R
P
P
Q
P
Site 17
S133
P
A
H
G
L
H
A
S
H
V
L
Q
P
Q
L
Site 18
T163
R
C
E
A
A
P
A
T
P
G
V
P
A
G
G
Site 19
S183
P
L
L
L
A
D
K
S
P
L
G
L
K
G
K
Site 20
Y195
K
G
K
E
P
V
V
Y
P
W
M
K
K
I
H
Site 21
Y210
V
S
A
V
N
P
S
Y
N
G
G
E
P
K
R
Site 22
S218
N
G
G
E
P
K
R
S
R
T
A
Y
T
R
Q
Site 23
T220
G
E
P
K
R
S
R
T
A
Y
T
R
Q
Q
V
Site 24
Y222
P
K
R
S
R
T
A
Y
T
R
Q
Q
V
L
E
Site 25
Y239
K
E
F
H
F
N
R
Y
L
T
R
R
R
R
I
Site 26
T241
F
H
F
N
R
Y
L
T
R
R
R
R
I
E
I
Site 27
T251
R
R
I
E
I
A
H
T
L
C
L
S
E
R
Q
Site 28
T279
K
D
H
K
L
P
N
T
K
M
R
S
S
N
S
Site 29
S283
L
P
N
T
K
M
R
S
S
N
S
A
S
A
S
Site 30
S284
P
N
T
K
M
R
S
S
N
S
A
S
A
S
A
Site 31
S286
T
K
M
R
S
S
N
S
A
S
A
S
A
G
P
Site 32
S288
M
R
S
S
N
S
A
S
A
S
A
G
P
P
G
Site 33
S290
S
S
N
S
A
S
A
S
A
G
P
P
G
K
A
Site 34
T299
G
P
P
G
K
A
Q
T
Q
S
P
H
L
H
P
Site 35
S301
P
G
K
A
Q
T
Q
S
P
H
L
H
P
H
P
Site 36
S311
L
H
P
H
P
H
P
S
T
S
T
P
V
P
S
Site 37
T312
H
P
H
P
H
P
S
T
S
T
P
V
P
S
S
Site 38
S313
P
H
P
H
P
S
T
S
T
P
V
P
S
S
I
Site 39
T314
H
P
H
P
S
T
S
T
P
V
P
S
S
I
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation