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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TFAM
Full Name:
Transcription factor A, mitochondrial
Alias:
Mitochondrial transcription factor 1; MtTF1; MtTFA; TCF6; TCF6L2; Transcription factor 6-like 2
Type:
Transcription regulation
Mass (Da):
29097
Number AA:
246
UniProt ID:
Q00059
International Prot ID:
IPI00020928
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0042645
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006261
GO:0006356
GO:0006390
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T23
R
S
G
A
E
L
C
T
G
C
G
S
R
L
R
Site 2
S27
E
L
C
T
G
C
G
S
R
L
R
S
P
F
S
Site 3
S34
S
R
L
R
S
P
F
S
F
V
Y
L
P
R
W
Site 4
Y37
R
S
P
F
S
F
V
Y
L
P
R
W
F
S
S
Site 5
S43
V
Y
L
P
R
W
F
S
S
V
L
A
S
C
P
Site 6
S44
Y
L
P
R
W
F
S
S
V
L
A
S
C
P
K
Site 7
S55
S
C
P
K
K
P
V
S
S
Y
L
R
F
S
K
Site 8
S56
C
P
K
K
P
V
S
S
Y
L
R
F
S
K
E
Site 9
Y57
P
K
K
P
V
S
S
Y
L
R
F
S
K
E
Q
Site 10
S61
V
S
S
Y
L
R
F
S
K
E
Q
L
P
I
F
Site 11
S94
R
W
R
E
L
P
D
S
K
K
K
I
Y
Q
D
Site 12
Y103
K
K
I
Y
Q
D
A
Y
R
A
E
W
Q
V
Y
Site 13
Y110
Y
R
A
E
W
Q
V
Y
K
E
E
I
S
R
F
Site 14
T122
S
R
F
K
E
Q
L
T
P
S
Q
I
M
S
L
Site 15
S124
F
K
E
Q
L
T
P
S
Q
I
M
S
L
E
K
Site 16
S128
L
T
P
S
Q
I
M
S
L
E
K
E
I
M
D
Site 17
T150
M
T
K
K
K
E
L
T
L
L
G
K
P
K
R
Site 18
S160
G
K
P
K
R
P
R
S
A
Y
N
V
Y
V
A
Site 19
Y162
P
K
R
P
R
S
A
Y
N
V
Y
V
A
E
R
Site 20
Y165
P
R
S
A
Y
N
V
Y
V
A
E
R
F
Q
E
Site 21
S177
F
Q
E
A
K
G
D
S
P
Q
E
K
L
K
T
Site 22
T184
S
P
Q
E
K
L
K
T
V
K
E
N
W
K
N
Site 23
S193
K
E
N
W
K
N
L
S
D
S
E
K
E
L
Y
Site 24
S195
N
W
K
N
L
S
D
S
E
K
E
L
Y
I
Q
Site 25
Y200
S
D
S
E
K
E
L
Y
I
Q
H
A
K
E
D
Site 26
Y211
A
K
E
D
E
T
R
Y
H
N
E
M
K
S
W
Site 27
T234
R
K
D
L
L
R
R
T
I
K
K
Q
R
K
Y
Site 28
Y241
T
I
K
K
Q
R
K
Y
G
A
E
E
C
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation