PhosphoNET

           
Protein Info 
   
Short Name:  PITPNA
Full Name:  Phosphatidylinositol transfer protein alpha isoform
Alias:  Phosphatidylinositol transfer protein, alpha; PIPNA; PI-TP-alpha; PITPN; PPI1; PtdIns transfer protein alpha; PtdInsTP; VIB1A
Type:  Lipid binding protein
Mass (Da):  31806
Number AA:  270
UniProt ID:  Q00169
International Prot ID:  IPI00216048
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005634   Uniprot OncoNet
Molecular Function:  GO:0008525  GO:0008526  GO:0005515 PhosphoSite+ KinaseNET
Biological Process:  GO:0006629  GO:0007601   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y18LPVSVDEYQVGQLYS
Site 2Y24EYQVGQLYSVAEASK
Site 3S25YQVGQLYSVAEASKN
Site 4S30LYSVAEASKNETGGG
Site 5Y48EVLVNEPYEKDGEKG
Site 6Y57KDGEKGQYTHKIYHL
Site 7T58DGEKGQYTHKIYHLQ
Site 8Y62GQYTHKIYHLQSKVP
Site 9Y91HEKAWNAYPYCRTVI
Site 10Y93KAWNAYPYCRTVITN
Site 11Y140WKHVEAVYIDIADRS
Site 12S147YIDIADRSQVLSKDY
Site 13S151ADRSQVLSKDYKAEE
Site 14Y154SQVLSKDYKAEEDPA
Site 15S165EDPAKFKSIKTGRGP
Site 16T168AKFKSIKTGRGPLGP
Site 17Y189VNQKDCPYMCAYKLV
Site 18T222KQERRLFTNFHRQLF
Site 19T250IRRMEEETKRQLDEM
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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