PhosphoNET

           
Protein Info 
   
Short Name:  Cdc42EP1
Full Name:  Cdc42 effector protein 1
Alias:  55 kDa bone marrow stromal/endothelial cell protein; Binder of Rho GTPases 5; BORG5; CDC42 effector protein (Rho GTPase binding) 1; Cdc42 effector protein 1: Binder of Rho GTPases 5: Serum protein MSE55: Cdc42 effector protein 1: Binder of Rho GTPases 5: Serum protein MSE55; CDC42EP1; CEP1; MSE55; Serum constituent protein; Serum protein MSE55
Type:  GTPase activating protein, Rac/Rho
Mass (Da):  40295
Number AA:  391
UniProt ID:  Q00587
International Prot ID:  IPI00023605
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005856  GO:0019898 Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0005515  GO:0005488 PhosphoSite+ KinaseNET
Biological Process:  GO:0031274  GO:0008360  GO:0007242 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T12QGGRGAATMSLGKLS
Site 2S14GRGAATMSLGKLSPV
Site 3S19TMSLGKLSPVGWVSS
Site 4S26SPVGWVSSSQGKRRL
Site 5S27PVGWVSSSQGKRRLT
Site 6T34SQGKRRLTADMISHP
Site 7S39RLTADMISHPLGDFR
Site 8T48PLGDFRHTMHVGRGG
Site 9T61GGDVFGDTSFLSNHG
Site 10S62GDVFGDTSFLSNHGG
Site 11S65FGDTSFLSNHGGSSG
Site 12S70FLSNHGGSSGSTHRS
Site 13S71LSNHGGSSGSTHRSP
Site 14S73NHGGSSGSTHRSPRS
Site 15T74HGGSSGSTHRSPRSF
Site 16S77SSGSTHRSPRSFLAK
Site 17S80STHRSPRSFLAKKLQ
Site 18S101APPRRMASPPAPSPA
Site 19S106MASPPAPSPAPPAIS
Site 20S113SPAPPAISPIIKNAI
Site 21S121PIIKNAISLPQLNQA
Site 22Y130PQLNQAAYDSLVVGK
Site 23S132LNQAAYDSLVVGKLS
Site 24S139SLVVGKLSFDSSPTS
Site 25S142VGKLSFDSSPTSSTD
Site 26S143GKLSFDSSPTSSTDG
Site 27T145LSFDSSPTSSTDGHS
Site 28S146SFDSSPTSSTDGHSS
Site 29S147FDSSPTSSTDGHSSY
Site 30T148DSSPTSSTDGHSSYG
Site 31S152TSSTDGHSSYGLDSG
Site 32S153SSTDGHSSYGLDSGF
Site 33Y154STDGHSSYGLDSGFC
Site 34S158HSSYGLDSGFCTISR
Site 35T162GLDSGFCTISRLPRS
Site 36S164DSGFCTISRLPRSEK
Site 37S169TISRLPRSEKPHDRD
Site 38S180HDRDRDGSFPSEPGL
Site 39S183DRDGSFPSEPGLRRS
Site 40S190SEPGLRRSDSLLSFR
Site 41S192PGLRRSDSLLSFRLD
Site 42S195RRSDSLLSFRLDLDL
Site 43T224PEAPAAETPAPAANP
Site 44T235AANPPAPTANPTGPA
Site 45T248PAANPPATTANPPAP
Site 46S260PAPAANPSAPAATPT
Site 47T265NPSAPAATPTGPAAN
Site 48S279NPPAPAASSTPHGHC
Site 49S280PPAPAASSTPHGHCP
Site 50T281PAPAASSTPHGHCPN
Site 51S302GPVAEVKSSPVGGGP
Site 52S303PVAEVKSSPVGGGPR
Site 53Y331GWDGGHHYPEMDARQ
Site 54S350VLPQARASWESLDEE
Site 55S353QARASWESLDEEWRA
Site 56S365WRAPQAGSRTPVPST
Site 57T367APQAGSRTPVPSTVQ
Site 58S371GSRTPVPSTVQANTF
Site 59T372SRTPVPSTVQANTFE
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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