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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FANCC
Full Name:
Fanconi anemia group C protein
Alias:
FA3; FAC; FACC; Fanconi anemia group C; Fanconi anemia, complementation group C
Type:
Mass (Da):
63410
Number AA:
558
UniProt ID:
Q00597
International Prot ID:
IPI00023608
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006461
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
A
Q
D
S
V
D
L
S
C
D
Y
Site 2
Y12
S
V
D
L
S
C
D
Y
Q
F
W
M
Q
K
L
Site 3
T30
D
Q
A
S
T
L
E
T
Q
Q
D
T
C
L
H
Site 4
Y49
Q
E
F
L
R
K
M
Y
E
A
L
K
E
M
D
Site 5
S57
E
A
L
K
E
M
D
S
N
T
V
I
E
R
F
Site 6
T59
L
K
E
M
D
S
N
T
V
I
E
R
F
P
T
Site 7
S86
F
I
L
A
Y
D
E
S
Q
K
I
L
I
W
C
Site 8
S105
I
N
K
E
P
Q
N
S
G
Q
S
K
L
N
S
Site 9
S112
S
G
Q
S
K
L
N
S
W
I
Q
G
V
L
S
Site 10
Y145
L
G
Y
A
P
I
D
Y
Y
P
G
L
L
K
N
Site 11
Y146
G
Y
A
P
I
D
Y
Y
P
G
L
L
K
N
M
Site 12
S159
N
M
V
L
S
L
A
S
E
L
R
E
N
H
L
Site 13
T171
N
H
L
N
G
F
N
T
Q
R
R
M
A
P
E
Site 14
S249
L
W
L
R
H
L
P
S
L
E
K
A
M
L
H
Site 15
S263
H
L
F
E
K
L
I
S
S
E
R
N
C
L
R
Site 16
S264
L
F
E
K
L
I
S
S
E
R
N
C
L
R
R
Site 17
S280
E
C
F
I
K
D
S
S
L
P
Q
A
A
C
H
Site 18
T339
Q
L
R
F
A
L
K
T
Y
F
P
Y
T
S
P
Site 19
Y340
L
R
F
A
L
K
T
Y
F
P
Y
T
S
P
S
Site 20
T367
P
R
G
H
W
L
Q
T
L
K
H
I
S
E
L
Site 21
T383
R
E
A
V
E
D
Q
T
H
G
S
C
G
G
P
Site 22
S386
V
E
D
Q
T
H
G
S
C
G
G
P
F
E
S
Site 23
Y430
L
W
L
L
A
F
Y
Y
G
P
R
D
G
R
Q
Site 24
T442
G
R
Q
Q
R
A
Q
T
M
V
Q
V
K
A
V
Site 25
S459
H
L
L
A
M
S
R
S
S
S
L
S
A
Q
D
Site 26
S461
L
A
M
S
R
S
S
S
L
S
A
Q
D
L
Q
Site 27
S463
M
S
R
S
S
S
L
S
A
Q
D
L
Q
T
V
Site 28
T469
L
S
A
Q
D
L
Q
T
V
A
G
Q
G
T
D
Site 29
T477
V
A
G
Q
G
T
D
T
D
L
R
A
P
A
Q
Site 30
Y531
G
F
L
D
Q
T
L
Y
R
W
N
R
L
G
I
Site 31
S540
W
N
R
L
G
I
E
S
P
R
S
E
K
L
A
Site 32
S543
L
G
I
E
S
P
R
S
E
K
L
A
R
E
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation