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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
B4GALNT1
Full Name:
Beta-1,4 N-acetylgalactosaminyltransferase 1
Alias:
B4GN1; Beta-1,4-N-acetyl-galactosaminyl transferase 1; Beta1-4GalNAc-T; EC 2.4.1.92; GALGT; GALNACT; GalNAc-T; GD2 synthase, GM2 synthase; GM2/GD2 synthase; N- acetylneuraminyl; SIAT2
Type:
Transferase, Glycan Biosynthesis and Metabolism group, Glycosphingolipid biosynthesis - ganglioseries family, Glycan structures - biosynthesis 2 family
Mass (Da):
58882
Number AA:
533
UniProt ID:
Q00973
International Prot ID:
IPI00025473
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030173
GO:0005624
Uniprot
OncoNet
Molecular Function:
GO:0003947
PhosphoSite+
KinaseNET
Biological Process:
GO:0005975
GO:0030259
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T27
L
G
L
L
Y
A
S
T
R
D
A
P
G
L
R
Site 2
S45
A
P
W
A
P
P
Q
S
P
R
R
P
E
L
P
Site 3
Y60
D
L
A
P
E
P
R
Y
A
H
I
P
V
R
I
Site 4
S81
L
L
A
W
N
N
C
S
C
E
S
S
G
G
G
Site 5
S85
N
N
C
S
C
E
S
S
G
G
G
L
P
L
P
Site 6
T103
Q
V
R
A
I
D
L
T
K
A
F
D
P
A
E
Site 7
S115
P
A
E
L
R
A
A
S
A
T
R
E
Q
E
F
Site 8
S127
Q
E
F
Q
A
F
L
S
R
S
Q
S
P
A
D
Site 9
S129
F
Q
A
F
L
S
R
S
Q
S
P
A
D
Q
L
Site 10
Y147
P
A
N
S
P
L
Q
Y
P
L
Q
G
V
E
V
Site 11
T181
E
V
Y
Q
V
N
L
T
A
S
L
G
T
W
D
Site 12
T207
G
E
G
Q
A
D
L
T
L
V
S
P
G
L
D
Site 13
S210
Q
A
D
L
T
L
V
S
P
G
L
D
Q
L
N
Site 14
T224
N
R
Q
L
Q
L
V
T
Y
S
S
R
S
Y
Q
Site 15
Y225
R
Q
L
Q
L
V
T
Y
S
S
R
S
Y
Q
T
Site 16
S226
Q
L
Q
L
V
T
Y
S
S
R
S
Y
Q
T
N
Site 17
S227
L
Q
L
V
T
Y
S
S
R
S
Y
Q
T
N
T
Site 18
S229
L
V
T
Y
S
S
R
S
Y
Q
T
N
T
A
D
Site 19
Y230
V
T
Y
S
S
R
S
Y
Q
T
N
T
A
D
T
Site 20
T237
Y
Q
T
N
T
A
D
T
V
R
F
S
T
E
G
Site 21
S241
T
A
D
T
V
R
F
S
T
E
G
H
E
A
A
Site 22
T242
A
D
T
V
R
F
S
T
E
G
H
E
A
A
F
Site 23
T250
E
G
H
E
A
A
F
T
I
R
I
R
H
P
P
Site 24
Y262
H
P
P
N
P
R
L
Y
P
P
G
S
L
P
Q
Site 25
S266
P
R
L
Y
P
P
G
S
L
P
Q
G
A
Q
Y
Site 26
Y273
S
L
P
Q
G
A
Q
Y
N
I
S
A
L
V
T
Site 27
Y289
A
T
K
T
F
L
R
Y
D
R
L
R
A
L
I
Site 28
T297
D
R
L
R
A
L
I
T
S
I
R
R
F
Y
P
Site 29
S298
R
L
R
A
L
I
T
S
I
R
R
F
Y
P
T
Site 30
S314
T
V
V
I
A
D
D
S
D
K
P
E
R
V
S
Site 31
S321
S
D
K
P
E
R
V
S
G
P
Y
V
E
H
Y
Site 32
Y324
P
E
R
V
S
G
P
Y
V
E
H
Y
L
M
P
Site 33
Y328
S
G
P
Y
V
E
H
Y
L
M
P
F
G
K
G
Site 34
S345
A
G
R
N
L
A
V
S
Q
V
T
T
K
Y
V
Site 35
Y351
V
S
Q
V
T
T
K
Y
V
L
W
V
D
D
D
Site 36
T362
V
D
D
D
F
V
F
T
A
R
T
R
L
E
R
Site 37
T377
L
V
D
V
L
E
R
T
P
L
D
L
V
G
G
Site 38
S390
G
G
A
V
R
E
I
S
G
F
A
T
T
Y
R
Site 39
T394
R
E
I
S
G
F
A
T
T
Y
R
Q
L
L
S
Site 40
S401
T
T
Y
R
Q
L
L
S
V
E
P
G
A
P
G
Site 41
S485
D
V
V
V
D
H
A
S
K
L
K
L
P
W
T
Site 42
T492
S
K
L
K
L
P
W
T
S
R
D
A
G
A
E
Site 43
T500
S
R
D
A
G
A
E
T
Y
A
R
Y
R
Y
P
Site 44
Y501
R
D
A
G
A
E
T
Y
A
R
Y
R
Y
P
G
Site 45
Y504
G
A
E
T
Y
A
R
Y
R
Y
P
G
S
L
D
Site 46
Y506
E
T
Y
A
R
Y
R
Y
P
G
S
L
D
E
S
Site 47
S509
A
R
Y
R
Y
P
G
S
L
D
E
S
Q
M
A
Site 48
S513
Y
P
G
S
L
D
E
S
Q
M
A
K
H
R
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation