KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
IRF9
Full Name:
Interferon regulatory factor 9
Alias:
IFN-alpha-responsive transcription factor subunit;ISGF3 p48 subunit;Interferon-stimulated gene factor 3 gamma;Transcriptional regulator ISGF3 subunit gamma
Type:
Mass (Da):
43696
Number AA:
393
UniProt ID:
Q00978
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
A
S
G
R
A
R
C
T
R
K
L
R
N
W
V
Site 2
Y69
W
A
I
F
K
G
K
Y
K
E
G
D
T
G
G
Site 3
T74
G
K
Y
K
E
G
D
T
G
G
P
A
V
W
K
Site 4
T82
G
G
P
A
V
W
K
T
R
L
R
C
A
L
N
Site 5
S91
L
R
C
A
L
N
K
S
S
E
F
K
E
V
P
Site 6
Y109
R
M
D
V
A
E
P
Y
K
V
Y
Q
L
L
P
Site 7
T126
I
V
S
G
Q
P
G
T
Q
K
V
P
S
K
R
Site 8
S131
P
G
T
Q
K
V
P
S
K
R
Q
H
S
S
V
Site 9
S136
V
P
S
K
R
Q
H
S
S
V
S
S
E
R
K
Site 10
S137
P
S
K
R
Q
H
S
S
V
S
S
E
R
K
E
Site 11
S139
K
R
Q
H
S
S
V
S
S
E
R
K
E
E
E
Site 12
S140
R
Q
H
S
S
V
S
S
E
R
K
E
E
E
D
Site 13
T153
E
D
A
M
Q
N
C
T
L
S
P
S
V
L
Q
Site 14
S155
A
M
Q
N
C
T
L
S
P
S
V
L
Q
D
S
Site 15
S157
Q
N
C
T
L
S
P
S
V
L
Q
D
S
L
N
Site 16
S162
S
P
S
V
L
Q
D
S
L
N
N
E
E
E
G
Site 17
S177
A
S
G
G
A
V
H
S
D
I
G
S
S
S
S
Site 18
S181
A
V
H
S
D
I
G
S
S
S
S
S
S
S
P
Site 19
S182
V
H
S
D
I
G
S
S
S
S
S
S
S
P
E
Site 20
S183
H
S
D
I
G
S
S
S
S
S
S
S
P
E
P
Site 21
S184
S
D
I
G
S
S
S
S
S
S
S
P
E
P
Q
Site 22
S185
D
I
G
S
S
S
S
S
S
S
P
E
P
Q
E
Site 23
S186
I
G
S
S
S
S
S
S
S
P
E
P
Q
E
V
Site 24
S187
G
S
S
S
S
S
S
S
P
E
P
Q
E
V
T
Site 25
T196
E
P
Q
E
V
T
D
T
T
E
A
P
F
Q
G
Site 26
T197
P
Q
E
V
T
D
T
T
E
A
P
F
Q
G
D
Site 27
S207
P
F
Q
G
D
Q
R
S
L
E
F
L
L
P
P
Site 28
S248
C
R
L
V
A
E
P
S
G
S
E
S
S
M
E
Site 29
S250
L
V
A
E
P
S
G
S
E
S
S
M
E
Q
V
Site 30
S252
A
E
P
S
G
S
E
S
S
M
E
Q
V
L
F
Site 31
S253
E
P
S
G
S
E
S
S
M
E
Q
V
L
F
P
Site 32
T268
K
P
G
P
L
E
P
T
Q
R
L
L
S
Q
L
Site 33
S273
E
P
T
Q
R
L
L
S
Q
L
E
R
G
I
L
Site 34
S299
R
L
C
P
I
P
I
S
W
N
A
P
Q
A
P
Site 35
S316
P
G
P
H
L
L
P
S
N
E
C
V
E
L
F
Site 36
Y335
F
C
R
D
L
V
R
Y
F
Q
G
L
G
P
P
Site 37
T348
P
P
P
K
F
Q
V
T
L
N
F
W
E
E
S
Site 38
S355
T
L
N
F
W
E
E
S
H
G
S
S
H
T
P
Site 39
S358
F
W
E
E
S
H
G
S
S
H
T
P
Q
N
L
Site 40
S359
W
E
E
S
H
G
S
S
H
T
P
Q
N
L
I
Site 41
T361
E
S
H
G
S
S
H
T
P
Q
N
L
I
T
V
Site 42
T367
H
T
P
Q
N
L
I
T
V
K
M
E
Q
A
F
Site 43
T382
A
R
Y
L
L
E
Q
T
P
E
Q
Q
A
A
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation