PhosphoNET

           
Protein Info 
   
Short Name:  SFRS2
Full Name:  Serine/arginine-rich splicing factor 2
Alias:  PR264; PR264 protein; Protein PR264; SC35; SC-35; SFR2; SFRS2A; Splicing component, 35 kDa; Splicing factor SC35; Splicing factor, arginine/serine-rich 2
Type:  RNA binding protein, splicing factor
Mass (Da):  25476
Number AA:  221
UniProt ID:  Q01130
International Prot ID:  IPI00005978
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016607  GO:0016604  GO:0016605 Uniprot OncoNet
Molecular Function:  GO:0003723  GO:0000166  GO:0003714 PhosphoSite+ KinaseNET
Biological Process:  GO:0000398  GO:0008380  GO:0000398 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S2______MSYGRPPPD
Site 2S15PDVEGMTSLKVDNLT
Site 3T22SLKVDNLTYRTSPDT
Site 4Y23LKVDNLTYRTSPDTL
Site 5T25VDNLTYRTSPDTLRR
Site 6S26DNLTYRTSPDTLRRV
Site 7T29TYRTSPDTLRRVFEK
Site 8Y37LRRVFEKYGRVGDVY
Site 9Y44YGRVGDVYIPRDRYT
Site 10Y50VYIPRDRYTKESRGF
Site 11T51YIPRDRYTKESRGFA
Site 12S54RDRYTKESRGFAFVR
Site 13Y92LRVQMARYGRPPDSH
Site 14S98RYGRPPDSHHSRRGP
Site 15S101RPPDSHHSRRGPPPR
Site 16Y110RGPPPRRYGGGGYGR
Site 17Y115RRYGGGGYGRRSRSP
Site 18S119GGGYGRRSRSPRRRR
Site 19S121GYGRRSRSPRRRRRS
Site 20S128SPRRRRRSRSRSRSR
Site 21S130RRRRRSRSRSRSRSR
Site 22S132RRRSRSRSRSRSRSR
Site 23S134RSRSRSRSRSRSRSR
Site 24S138RSRSRSRSRSRSRYS
Site 25S140RSRSRSRSRSRYSRS
Site 26S142RSRSRSRSRYSRSKS
Site 27Y144RSRSRSRYSRSKSRS
Site 28S145SRSRSRYSRSKSRSR
Site 29S147SRSRYSRSKSRSRTR
Site 30S149SRYSRSKSRSRTRSR
Site 31S151YSRSKSRSRTRSRSR
Site 32T153RSKSRSRTRSRSRST
Site 33S155KSRSRTRSRSRSTSK
Site 34S157RSRTRSRSRSTSKSR
Site 35S159RTRSRSRSTSKSRSA
Site 36T160TRSRSRSTSKSRSAR
Site 37S161RSRSRSTSKSRSARR
Site 38S163RSRSTSKSRSARRSK
Site 39S165RSTSKSRSARRSKSK
Site 40S169KSRSARRSKSKSSSV
Site 41S171RSARRSKSKSSSVSR
Site 42S173ARRSKSKSSSVSRSR
Site 43S174RRSKSKSSSVSRSRS
Site 44S175RSKSKSSSVSRSRSR
Site 45S177KSKSSSVSRSRSRSR
Site 46S179KSSSVSRSRSRSRSR
Site 47S181SSVSRSRSRSRSRSR
Site 48S183VSRSRSRSRSRSRSR
Site 49S185RSRSRSRSRSRSRSP
Site 50S187RSRSRSRSRSRSPPP
Site 51S189RSRSRSRSRSPPPVS
Site 52S191RSRSRSRSPPPVSKR
Site 53S196SRSPPPVSKRESKSR
Site 54S200PPVSKRESKSRSRSK
Site 55S202VSKRESKSRSRSKSP
Site 56S204KRESKSRSRSKSPPK
Site 57S206ESKSRSRSKSPPKSP
Site 58S208KSRSRSKSPPKSPEE
Site 59S212RSKSPPKSPEEEGAV
Site 60S220PEEEGAVSS______
Site 61S221EEEGAVSS_______
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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