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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
POU4F1
Full Name:
POU domain, class 4, transcription factor 1
Alias:
Brn3a; Oct-t1; Po4f1; Pou class 4 homeobox 1; Pou domain, class 4, transcription factor 1; Pou4f1; Rdc-1
Type:
Transcription factor, Cell development/differentiation
Mass (Da):
42754
Number AA:
420
UniProt ID:
Q01851
International Prot ID:
IPI00009864
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0043565
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0007409
GO:0006357
GO:0007416
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T16
P
H
F
A
M
H
P
T
L
P
E
H
K
Y
P
Site 2
Y22
P
T
L
P
E
H
K
Y
P
S
L
H
S
S
S
Site 3
S24
L
P
E
H
K
Y
P
S
L
H
S
S
S
E
A
Site 4
S28
K
Y
P
S
L
H
S
S
S
E
A
I
R
R
A
Site 5
S29
Y
P
S
L
H
S
S
S
E
A
I
R
R
A
C
Site 6
T39
I
R
R
A
C
L
P
T
P
P
L
Q
S
N
L
Site 7
S73
I
A
V
S
Q
G
K
S
H
P
F
K
P
D
A
Site 8
Y82
P
F
K
P
D
A
T
Y
H
T
M
N
S
V
P
Site 9
T84
K
P
D
A
T
Y
H
T
M
N
S
V
P
C
T
Site 10
S87
A
T
Y
H
T
M
N
S
V
P
C
T
S
T
S
Site 11
S94
S
V
P
C
T
S
T
S
T
V
P
L
A
H
H
Site 12
T95
V
P
C
T
S
T
S
T
V
P
L
A
H
H
H
Site 13
S121
G
D
L
L
D
H
I
S
S
P
S
L
A
L
M
Site 14
S122
D
L
L
D
H
I
S
S
P
S
L
A
L
M
A
Site 15
S187
G
G
G
L
L
G
G
S
A
H
P
H
P
H
M
Site 16
S196
H
P
H
P
H
M
H
S
L
G
H
L
S
H
P
Site 17
S262
G
L
A
S
I
C
D
S
D
T
D
P
R
E
L
Site 18
T264
A
S
I
C
D
S
D
T
D
P
R
E
L
E
A
Site 19
T286
R
R
I
K
L
G
V
T
Q
A
D
V
G
S
A
Site 20
S308
G
V
G
S
L
S
Q
S
T
I
C
R
F
E
S
Site 21
S315
S
T
I
C
R
F
E
S
L
T
L
S
H
N
N
Site 22
S319
R
F
E
S
L
T
L
S
H
N
N
M
I
A
L
Site 23
T361
G
E
K
K
R
K
R
T
S
I
A
A
P
E
K
Site 24
S362
E
K
K
R
K
R
T
S
I
A
A
P
E
K
R
Site 25
Y374
E
K
R
S
L
E
A
Y
F
A
V
Q
P
R
P
Site 26
S382
F
A
V
Q
P
R
P
S
S
E
K
I
A
A
I
Site 27
S383
A
V
Q
P
R
P
S
S
E
K
I
A
A
I
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation