PhosphoNET

           
Protein Info 
   
Short Name:  POU5F1
Full Name:  POU domain, class 5, transcription factor 1
Alias:  OCT3; Oct-3; OCT4; Oct-4; Octamer-binding transcription factor 3; OTF3; PO5F1
Type:  Transcription protein. POU transcription factor family. Class-5 subfamily.
Mass (Da):  38571
Number AA:  360
UniProt ID:  Q01860
International Prot ID:  IsoformA - IPI00219089
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005829  GO:0005634   Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0043565  GO:0003700 PhosphoSite+ KinaseNET
Biological Process:  GO:0009653  GO:0006355  GO:0035019 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S12LASDFAFSPPPGGGG
Site 2T34PGWVDPRTWLSFQGP
Site 3S37VDPRTWLSFQGPPGG
Site 4S55GPGVGPGSEVWGIPP
Site 5T92VPQGGLETSQPEGEA
Site 6S93PQGGLETSQPEGEAG
Site 7S105EAGVGVESNSDGASP
Site 8S107GVGVESNSDGASPEP
Site 9S111ESNSDGASPEPCTVT
Site 10T116GASPEPCTVTPGAVK
Site 11T118SPEPCTVTPGAVKLE
Site 12T159LLKQKRITLGYTQAD
Site 13Y162QKRITLGYTQADVGL
Site 14T163KRITLGYTQADVGLT
Site 15S180VLFGKVFSQTTICRF
Site 16S193RFEALQLSFKNMCKL
Site 17T235QARKRKRTSIENRVR
Site 18S236ARKRKRTSIENRVRG
Site 19S288RRQKGKRSSSDYAQR
Site 20S289RQKGKRSSSDYAQRE
Site 21S290QKGKRSSSDYAQRED
Site 22Y292GKRSSSDYAQREDFE
Site 23S303EDFEAAGSPFSGGPV
Site 24S306EAAGSPFSGGPVSFP
Site 25T322APGPHFGTPGYGSPH
Site 26Y325PHFGTPGYGSPHFTA
Site 27S327FGTPGYGSPHFTALY
Site 28T331GYGSPHFTALYSSVP
Site 29Y334SPHFTALYSSVPFPE
Site 30S335PHFTALYSSVPFPEG
Site 31T352FPPVSVTTLGSPMHS
Site 32S355VSVTTLGSPMHSN__
Site 33S359TLGSPMHSN______
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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