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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC6A3
Full Name:
Sodium-dependent dopamine transporter
Alias:
DA transporter; DAT1; Dopamine transporter; S6A3; SC6A3; Solute carrier family 6 (neurotransmitter transporter, dopamine) member 3; Solute carrier family 6 member 3
Type:
Transport protein
Mass (Da):
68495
Number AA:
620
UniProt ID:
Q01959
International Prot ID:
IPI00219765
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005887
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005330
GO:0008504
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006836
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
K
S
K
C
S
V
G
Site 2
S4
_
_
_
_
M
S
K
S
K
C
S
V
G
L
M
Site 3
S7
_
M
S
K
S
K
C
S
V
G
L
M
S
S
V
Site 4
S12
K
C
S
V
G
L
M
S
S
V
V
A
P
A
K
Site 5
S13
C
S
V
G
L
M
S
S
V
V
A
P
A
K
E
Site 6
S45
N
G
V
Q
L
T
S
S
T
L
T
N
P
R
Q
Site 7
T48
Q
L
T
S
S
T
L
T
N
P
R
Q
S
P
V
Site 8
S53
T
L
T
N
P
R
Q
S
P
V
E
A
Q
D
R
Site 9
T62
V
E
A
Q
D
R
E
T
W
G
K
K
I
D
F
Site 10
Y88
A
N
V
W
R
F
P
Y
L
C
Y
K
N
G
G
Site 11
Y91
W
R
F
P
Y
L
C
Y
K
N
G
G
G
A
F
Site 12
T261
S
L
W
K
G
V
K
T
S
G
K
V
V
W
I
Site 13
S262
L
W
K
G
V
K
T
S
G
K
V
V
W
I
T
Site 14
T286
A
L
L
L
R
G
V
T
L
P
G
A
I
D
G
Site 15
S334
G
V
L
I
A
F
S
S
Y
N
K
F
T
N
N
Site 16
S376
G
Y
M
A
Q
K
H
S
V
P
I
G
D
V
A
Site 17
T512
S
D
D
I
Q
Q
M
T
G
Q
R
P
S
L
Y
Site 18
Y519
T
G
Q
R
P
S
L
Y
W
R
L
C
W
K
L
Site 19
Y548
V
T
F
R
P
P
H
Y
G
A
Y
I
F
P
D
Site 20
Y551
R
P
P
H
Y
G
A
Y
I
F
P
D
W
A
N
Site 21
S582
Y
A
A
Y
K
F
C
S
L
P
G
S
F
R
E
Site 22
S586
K
F
C
S
L
P
G
S
F
R
E
K
L
A
Y
Site 23
Y593
S
F
R
E
K
L
A
Y
A
I
A
P
E
K
D
Site 24
T613
R
G
E
V
R
Q
F
T
L
R
H
W
L
K
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation