PhosphoNET

           
Protein Info 
   
Short Name:  ROR1
Full Name:  Tyrosine-protein kinase transmembrane receptor ROR1
Alias:  EC 2.7.1.112; EC 2.7.10.1; NTRKR1
Type:  Protein-tyrosine kinase (receptor), TK group, Ror family, N/A subfamily
Mass (Da):  104283
Number AA:  937
UniProt ID:  Q01973
International Prot ID:  IPI00010405
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005887   Uniprot OncoNet
Molecular Function:  GO:0005524  GO:0005515  GO:0004714 PhosphoSite+ KinaseNET
Biological Process:  GO:0006468  GO:0007169   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T9HRPRRRGTRPPLLAL
Site 2Y160PPTASPGYSDEYEED
Site 3S161PTASPGYSDEYEEDG
Site 4Y173EDGFCQPYRGIACAR
Site 5S434VCRNNQKSSSAPVQR
Site 6S436RNNQKSSSAPVQRQP
Site 7Y459EMSMLNAYKPKSKAK
Site 8S463LNAYKPKSKAKELPL
Site 9S471KAKELPLSAVRFMEE
Site 10Y488ECAFGKIYKGHLYLP
Site 11Y493KIYKGHLYLPGMDHA
Site 12T507AQLVAIKTLKDYNNP
Site 13Y511AIKTLKDYNNPQQWT
Site 14S525TEFQQEASLMAELHH
Site 15S568HEFLIMRSPHSDVGC
Site 16S571LIMRSPHSDVGCSSD
Site 17S577HSDVGCSSDEDGTVK
Site 18T582CSSDEDGTVKSSLDH
Site 19S585DEDGTVKSSLDHGDF
Site 20S632EQLHVKISDLGLSRE
Site 21S637KISDLGLSREIYSAD
Site 22Y641LGLSREIYSADYYRV
Site 23Y645REIYSADYYRVQSKS
Site 24Y646EIYSADYYRVQSKSL
Site 25S650ADYYRVQSKSLLPIR
Site 26S652YYRVQSKSLLPIRWM
Site 27Y666MPPEAIMYGKFSSDS
Site 28S673YGKFSSDSDIWSFGV
Site 29S677SSDSDIWSFGVVLWE
Site 30Y693FSFGLQPYYGFSNQE
Site 31Y694SFGLQPYYGFSNQEV
Site 32S714KRQLLPCSEDCPPRM
Site 33S748DIHVRLRSWEGLSSH
Site 34S753LRSWEGLSSHTSSTT
Site 35S754RSWEGLSSHTSSTTP
Site 36S757EGLSSHTSSTTPSGG
Site 37S758GLSSHTSSTTPSGGN
Site 38T760SSHTSSTTPSGGNAT
Site 39S762HTSSTTPSGGNATTQ
Site 40T768PSGGNATTQTTSLSA
Site 41T770GGNATTQTTSLSASP
Site 42S772NATTQTTSLSASPVS
Site 43S774TTQTTSLSASPVSNL
Site 44S776QTTSLSASPVSNLSN
Site 45S779SLSASPVSNLSNPRY
Site 46S782ASPVSNLSNPRYPNY
Site 47Y786SNLSNPRYPNYMFPS
Site 48Y789SNPRYPNYMFPSQGI
Site 49T797MFPSQGITPQGQIAG
Site 50Y822RFIPINGYPIPPGYA
Site 51Y828GYPIPPGYAAFPAAH
Site 52Y836AAFPAAHYQPTGPPR
Site 53T839PAAHYQPTGPPRVIQ
Site 54S853QHCPPPKSRSPSSAS
Site 55S855CPPPKSRSPSSASGS
Site 56S857PPKSRSPSSASGSTS
Site 57S858PKSRSPSSASGSTST
Site 58S860SRSPSSASGSTSTGH
Site 59S862SPSSASGSTSTGHVT
Site 60S864SSASGSTSTGHVTSL
Site 61T869STSTGHVTSLPSSGS
Site 62S870TSTGHVTSLPSSGSN
Site 63S874HVTSLPSSGSNQEAN
Site 64S876TSLPSSGSNQEANIP
Site 65S889IPLLPHMSIPNHPGG
Site 66T900HPGGMGITVFGNKSQ
Site 67S906ITVFGNKSQKPYKID
Site 68Y910GNKSQKPYKIDSKQA
Site 69S914QKPYKIDSKQASLLG
Site 70S918KIDSKQASLLGDANI
Site 71S931NIHGHTESMISAEL_
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


Click here to download a PPT of the image above

2019 Kinexus Bioinformatics Corporation