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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MEF2A
Full Name:
Myocyte-specific enhancer factor 2A
Alias:
MEF2; myocyte enhancer factor 2A; RSRFC4; RSRFC9; Serum response factor-like protein 1
Type:
Transcription protein
Mass (Da):
54811
Number AA:
507
UniProt ID:
Q02078
International Prot ID:
IPI00398406
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0043565
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0030154
GO:0007517
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T20
D
E
R
N
R
Q
V
T
F
T
K
R
K
F
G
Site 2
T22
R
N
R
Q
V
T
F
T
K
R
K
F
G
L
M
Site 3
Y57
S
S
N
K
L
F
Q
Y
A
S
T
D
M
D
K
Site 4
S59
N
K
L
F
Q
Y
A
S
T
D
M
D
K
V
L
Site 5
Y69
M
D
K
V
L
L
K
Y
T
E
Y
N
E
P
H
Site 6
T70
D
K
V
L
L
K
Y
T
E
Y
N
E
P
H
E
Site 7
Y72
V
L
L
K
Y
T
E
Y
N
E
P
H
E
S
R
Site 8
S78
E
Y
N
E
P
H
E
S
R
T
N
S
D
I
V
Site 9
S82
P
H
E
S
R
T
N
S
D
I
V
E
A
L
N
Site 10
S98
K
E
H
R
G
C
D
S
P
D
P
D
T
S
Y
Site 11
T103
C
D
S
P
D
P
D
T
S
Y
V
L
T
P
H
Site 12
S104
D
S
P
D
P
D
T
S
Y
V
L
T
P
H
T
Site 13
Y105
S
P
D
P
D
T
S
Y
V
L
T
P
H
T
E
Site 14
T108
P
D
T
S
Y
V
L
T
P
H
T
E
E
K
Y
Site 15
T111
S
Y
V
L
T
P
H
T
E
E
K
Y
K
K
I
Site 16
Y115
T
P
H
T
E
E
K
Y
K
K
I
N
E
E
F
Site 17
S143
P
P
Q
N
F
S
M
S
V
T
V
P
V
T
S
Site 18
T145
Q
N
F
S
M
S
V
T
V
P
V
T
S
P
N
Site 19
S155
V
T
S
P
N
A
L
S
Y
T
N
P
G
S
S
Site 20
Y156
T
S
P
N
A
L
S
Y
T
N
P
G
S
S
L
Site 21
T157
S
P
N
A
L
S
Y
T
N
P
G
S
S
L
V
Site 22
S161
L
S
Y
T
N
P
G
S
S
L
V
S
P
S
L
Site 23
S162
S
Y
T
N
P
G
S
S
L
V
S
P
S
L
A
Site 24
S165
N
P
G
S
S
L
V
S
P
S
L
A
A
S
S
Site 25
S171
V
S
P
S
L
A
A
S
S
T
L
T
D
S
S
Site 26
S172
S
P
S
L
A
A
S
S
T
L
T
D
S
S
M
Site 27
S177
A
S
S
T
L
T
D
S
S
M
L
S
P
P
Q
Site 28
S178
S
S
T
L
T
D
S
S
M
L
S
P
P
Q
T
Site 29
S181
L
T
D
S
S
M
L
S
P
P
Q
T
T
L
H
Site 30
T185
S
M
L
S
P
P
Q
T
T
L
H
R
N
V
S
Site 31
S192
T
T
L
H
R
N
V
S
P
G
A
P
Q
R
P
Site 32
S201
G
A
P
Q
R
P
P
S
T
G
N
A
G
G
M
Site 33
T202
A
P
Q
R
P
P
S
T
G
N
A
G
G
M
L
Site 34
S222
T
V
P
N
G
A
G
S
S
P
V
G
N
G
F
Site 35
S223
V
P
N
G
A
G
S
S
P
V
G
N
G
F
V
Site 36
S235
G
F
V
N
S
R
A
S
P
N
L
I
G
A
T
Site 37
T242
S
P
N
L
I
G
A
T
G
A
N
S
L
G
K
Site 38
S246
I
G
A
T
G
A
N
S
L
G
K
V
M
P
T
Site 39
T253
S
L
G
K
V
M
P
T
K
S
P
P
P
P
G
Site 40
S255
G
K
V
M
P
T
K
S
P
P
P
P
G
G
G
Site 41
S268
G
G
N
L
G
M
N
S
R
K
P
D
L
R
V
Site 42
S289
K
G
M
M
P
P
L
S
E
E
E
E
L
E
L
Site 43
T298
E
E
E
L
E
L
N
T
Q
R
I
S
S
S
Q
Site 44
S302
E
L
N
T
Q
R
I
S
S
S
Q
A
T
Q
P
Site 45
S303
L
N
T
Q
R
I
S
S
S
Q
A
T
Q
P
L
Site 46
S304
N
T
Q
R
I
S
S
S
Q
A
T
Q
P
L
A
Site 47
T307
R
I
S
S
S
Q
A
T
Q
P
L
A
T
P
V
Site 48
T312
Q
A
T
Q
P
L
A
T
P
V
V
S
V
T
T
Site 49
T319
T
P
V
V
S
V
T
T
P
S
L
P
P
Q
G
Site 50
S330
P
P
Q
G
L
V
Y
S
A
M
P
T
A
Y
N
Site 51
T334
L
V
Y
S
A
M
P
T
A
Y
N
T
D
Y
S
Site 52
Y340
P
T
A
Y
N
T
D
Y
S
L
T
S
A
D
L
Site 53
S341
T
A
Y
N
T
D
Y
S
L
T
S
A
D
L
S
Site 54
S344
N
T
D
Y
S
L
T
S
A
D
L
S
A
L
Q
Site 55
S348
S
L
T
S
A
D
L
S
A
L
Q
G
F
N
S
Site 56
S355
S
A
L
Q
G
F
N
S
P
G
M
L
S
L
G
Site 57
S390
G
G
Q
L
S
Q
G
S
N
L
S
I
N
T
N
Site 58
S393
L
S
Q
G
S
N
L
S
I
N
T
N
Q
N
I
Site 59
S401
I
N
T
N
Q
N
I
S
I
K
S
E
P
I
S
Site 60
S404
N
Q
N
I
S
I
K
S
E
P
I
S
P
P
R
Site 61
S408
S
I
K
S
E
P
I
S
P
P
R
D
R
M
T
Site 62
T415
S
P
P
R
D
R
M
T
P
S
G
F
Q
Q
Q
Site 63
S453
P
R
Q
E
M
G
R
S
P
V
D
S
L
S
S
Site 64
S457
M
G
R
S
P
V
D
S
L
S
S
S
S
S
S
Site 65
S459
R
S
P
V
D
S
L
S
S
S
S
S
S
Y
D
Site 66
S460
S
P
V
D
S
L
S
S
S
S
S
S
Y
D
G
Site 67
S461
P
V
D
S
L
S
S
S
S
S
S
Y
D
G
S
Site 68
S462
V
D
S
L
S
S
S
S
S
S
Y
D
G
S
D
Site 69
S463
D
S
L
S
S
S
S
S
S
Y
D
G
S
D
R
Site 70
S464
S
L
S
S
S
S
S
S
Y
D
G
S
D
R
E
Site 71
S468
S
S
S
S
Y
D
G
S
D
R
E
D
P
R
G
Site 72
S479
D
P
R
G
D
F
H
S
P
I
V
L
G
R
P
Site 73
T489
V
L
G
R
P
P
N
T
E
D
R
E
S
P
S
Site 74
S494
P
N
T
E
D
R
E
S
P
S
V
K
R
M
R
Site 75
S496
T
E
D
R
E
S
P
S
V
K
R
M
R
M
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation