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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIF23
Full Name:
Kinesin-like protein KIF23
Alias:
CHO1; Kinesin family member 23; Kinesin-like 5; KNSL5; Mitotic kinesin-like 1; MKLP1; MKLP-1
Type:
Motor protein; Microtubule binding protein
Mass (Da):
110059
Number AA:
960
UniProt ID:
Q02241
International Prot ID:
IPI00291579
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005871
GO:0005874
GO:0030496
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0003777
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0051301
GO:0007018
GO:0007067
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
K
S
A
R
A
K
T
P
R
K
P
T
V
K
Site 2
T13
A
K
T
P
R
K
P
T
V
K
K
G
S
Q
T
Site 3
S18
K
P
T
V
K
K
G
S
Q
T
N
L
K
D
P
Site 4
T20
T
V
K
K
G
S
Q
T
N
L
K
D
P
V
G
Site 5
Y29
L
K
D
P
V
G
V
Y
C
R
V
R
P
L
G
Site 6
T56
N
T
T
V
Q
L
H
T
P
E
G
Y
R
L
N
Site 7
Y68
R
L
N
R
N
G
D
Y
K
E
T
Q
Y
S
F
Site 8
S74
D
Y
K
E
T
Q
Y
S
F
K
Q
V
F
G
T
Site 9
Y111
K
N
G
L
L
F
T
Y
G
V
T
G
S
G
K
Site 10
T121
T
G
S
G
K
T
H
T
M
T
G
S
P
G
E
Site 11
T123
S
G
K
T
H
T
M
T
G
S
P
G
E
G
G
Site 12
S125
K
T
H
T
M
T
G
S
P
G
E
G
G
L
L
Site 13
Y151
G
S
F
Q
A
K
R
Y
V
F
K
S
N
D
R
Site 14
S155
A
K
R
Y
V
F
K
S
N
D
R
N
S
M
D
Site 15
S160
F
K
S
N
D
R
N
S
M
D
I
Q
C
E
V
Site 16
T184
E
A
M
P
N
P
K
T
S
S
S
K
R
Q
V
Site 17
S187
P
N
P
K
T
S
S
S
K
R
Q
V
D
P
E
Site 18
S214
A
E
E
V
D
E
D
S
V
Y
G
V
F
V
S
Site 19
Y231
E
I
Y
N
N
Y
I
Y
D
L
L
E
E
V
P
Site 20
S249
I
K
P
K
P
P
Q
S
K
L
L
R
E
D
K
Site 21
Y261
E
D
K
N
H
N
M
Y
V
A
G
C
T
E
V
Site 22
T273
T
E
V
E
V
K
S
T
E
E
A
F
E
V
F
Site 23
T292
K
K
R
R
I
A
N
T
H
L
N
R
E
S
S
Site 24
S298
N
T
H
L
N
R
E
S
S
R
S
H
S
V
F
Site 25
S299
T
H
L
N
R
E
S
S
R
S
H
S
V
F
N
Site 26
S301
L
N
R
E
S
S
R
S
H
S
V
F
N
I
K
Site 27
S303
R
E
S
S
R
S
H
S
V
F
N
I
K
L
V
Site 28
S331
E
K
E
Q
I
T
I
S
Q
L
S
L
V
D
L
Site 29
S341
S
L
V
D
L
A
G
S
E
R
T
N
R
T
R
Site 30
S363
E
A
G
N
I
N
Q
S
L
M
T
L
R
T
C
Site 31
T369
Q
S
L
M
T
L
R
T
C
M
D
V
L
R
E
Site 32
Y380
V
L
R
E
N
Q
M
Y
G
T
N
K
M
V
P
Site 33
S391
K
M
V
P
Y
R
D
S
K
L
T
H
L
F
K
Site 34
T394
P
Y
R
D
S
K
L
T
H
L
F
K
N
Y
F
Site 35
Y400
L
T
H
L
F
K
N
Y
F
D
G
E
G
K
V
Site 36
Y420
V
N
P
K
A
E
D
Y
E
E
N
L
Q
V
M
Site 37
T450
D
K
A
I
C
G
L
T
P
G
R
R
Y
R
N
Site 38
Y455
G
L
T
P
G
R
R
Y
R
N
Q
P
R
G
P
Site 39
S482
Q
S
F
P
P
L
P
S
C
E
I
L
D
I
N
Site 40
T493
L
D
I
N
D
E
Q
T
L
P
R
L
I
E
A
Site 41
S552
N
E
K
E
K
M
I
S
G
Q
K
L
E
I
E
Site 42
T567
R
L
E
K
K
N
K
T
L
E
Y
K
I
E
I
Site 43
T580
E
I
L
E
K
T
T
T
I
Y
E
E
D
K
R
Site 44
Y582
L
E
K
T
T
T
I
Y
E
E
D
K
R
N
L
Site 45
S605
Q
K
L
Q
R
Q
F
S
D
K
R
R
L
E
A
Site 46
T663
A
I
V
T
E
P
K
T
E
K
P
E
R
P
S
Site 47
S670
T
E
K
P
E
R
P
S
R
E
R
D
R
E
K
Site 48
T679
E
R
D
R
E
K
V
T
Q
R
S
V
S
P
S
Site 49
S682
R
E
K
V
T
Q
R
S
V
S
P
S
P
V
P
Site 50
S684
K
V
T
Q
R
S
V
S
P
S
P
V
P
L
S
Site 51
S686
T
Q
R
S
V
S
P
S
P
V
P
L
S
S
N
Site 52
S691
S
P
S
P
V
P
L
S
S
N
Y
I
A
Q
I
Site 53
S692
P
S
P
V
P
L
S
S
N
Y
I
A
Q
I
S
Site 54
S699
S
N
Y
I
A
Q
I
S
N
G
Q
Q
L
M
S
Site 55
S706
S
N
G
Q
Q
L
M
S
Q
P
Q
L
H
R
R
Site 56
S714
Q
P
Q
L
H
R
R
S
N
S
C
S
S
I
S
Site 57
S716
Q
L
H
R
R
S
N
S
C
S
S
I
S
V
A
Site 58
S718
H
R
R
S
N
S
C
S
S
I
S
V
A
S
C
Site 59
S719
R
R
S
N
S
C
S
S
I
S
V
A
S
C
I
Site 60
T735
E
W
E
Q
K
I
P
T
Y
N
T
P
L
K
V
Site 61
Y736
W
E
Q
K
I
P
T
Y
N
T
P
L
K
V
T
Site 62
T738
Q
K
I
P
T
Y
N
T
P
L
K
V
T
S
I
Site 63
S744
N
T
P
L
K
V
T
S
I
A
R
R
R
Q
Q
Site 64
S756
R
Q
Q
E
P
G
Q
S
K
T
C
I
V
S
D
Site 65
T758
Q
E
P
G
Q
S
K
T
C
I
V
S
D
R
R
Site 66
S762
Q
S
K
T
C
I
V
S
D
R
R
R
G
M
Y
Site 67
Y769
S
D
R
R
R
G
M
Y
W
T
E
G
R
E
V
Site 68
T771
R
R
R
G
M
Y
W
T
E
G
R
E
V
V
P
Site 69
T779
E
G
R
E
V
V
P
T
F
R
N
E
I
E
I
Site 70
S812
I
R
L
R
H
R
R
S
R
S
A
G
D
R
W
Site 71
S814
L
R
H
R
R
S
R
S
A
G
D
R
W
V
D
Site 72
T830
K
P
A
S
N
M
Q
T
E
T
V
M
Q
P
H
Site 73
T843
P
H
V
P
H
A
I
T
V
S
V
A
N
E
K
Site 74
T861
K
C
E
K
Y
M
L
T
H
Q
E
L
A
S
D
Site 75
S867
L
T
H
Q
E
L
A
S
D
G
E
I
E
T
K
Site 76
T873
A
S
D
G
E
I
E
T
K
L
I
K
G
D
I
Site 77
Y881
K
L
I
K
G
D
I
Y
K
T
R
G
G
G
Q
Site 78
T883
I
K
G
D
I
Y
K
T
R
G
G
G
Q
S
V
Site 79
S889
K
T
R
G
G
G
Q
S
V
Q
F
T
D
I
E
Site 80
T893
G
G
Q
S
V
Q
F
T
D
I
E
T
L
K
Q
Site 81
T897
V
Q
F
T
D
I
E
T
L
K
Q
E
S
P
N
Site 82
S902
I
E
T
L
K
Q
E
S
P
N
G
S
R
K
R
Site 83
S906
K
Q
E
S
P
N
G
S
R
K
R
R
S
S
T
Site 84
S911
N
G
S
R
K
R
R
S
S
T
V
A
P
A
Q
Site 85
S912
G
S
R
K
R
R
S
S
T
V
A
P
A
Q
P
Site 86
T913
S
R
K
R
R
S
S
T
V
A
P
A
Q
P
D
Site 87
S924
A
Q
P
D
G
A
E
S
E
W
T
D
V
E
T
Site 88
T927
D
G
A
E
S
E
W
T
D
V
E
T
R
C
S
Site 89
S934
T
D
V
E
T
R
C
S
V
A
V
E
M
R
A
Site 90
S943
A
V
E
M
R
A
G
S
Q
L
G
P
G
Y
Q
Site 91
Y949
G
S
Q
L
G
P
G
Y
Q
H
H
A
Q
P
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation