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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SEMG2
Full Name:
Semenogelin-2
Alias:
Semenogelin II
Type:
Mass (Da):
65444
Number AA:
582
UniProt ID:
Q02383
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
K
S
I
I
L
F
V
L
S
Site 2
S28
V
M
G
Q
K
G
G
S
K
G
Q
L
P
S
G
Site 3
S34
G
S
K
G
Q
L
P
S
G
S
S
Q
F
P
H
Site 4
S36
K
G
Q
L
P
S
G
S
S
Q
F
P
H
G
Q
Site 5
S37
G
Q
L
P
S
G
S
S
Q
F
P
H
G
Q
K
Site 6
Y48
H
G
Q
K
G
Q
H
Y
F
G
Q
K
D
Q
Q
Site 7
S59
K
D
Q
Q
H
T
K
S
K
G
S
F
S
I
Q
Site 8
S62
Q
H
T
K
S
K
G
S
F
S
I
Q
H
T
Y
Site 9
S64
T
K
S
K
G
S
F
S
I
Q
H
T
Y
H
V
Site 10
T68
G
S
F
S
I
Q
H
T
Y
H
V
D
I
N
D
Site 11
Y69
S
F
S
I
Q
H
T
Y
H
V
D
I
N
D
H
Site 12
Y85
W
T
R
K
S
Q
Q
Y
D
L
N
A
L
H
K
Site 13
S96
A
L
H
K
A
T
K
S
K
Q
H
L
G
G
S
Site 14
S103
S
K
Q
H
L
G
G
S
Q
Q
L
L
N
Y
K
Site 15
T139
G
G
Q
A
H
H
G
T
Q
N
P
S
Q
D
Q
Site 16
S143
H
H
G
T
Q
N
P
S
Q
D
Q
G
N
S
P
Site 17
S149
P
S
Q
D
Q
G
N
S
P
S
G
K
G
L
S
Site 18
S151
Q
D
Q
G
N
S
P
S
G
K
G
L
S
S
Q
Site 19
S156
S
P
S
G
K
G
L
S
S
Q
C
S
N
T
E
Site 20
S157
P
S
G
K
G
L
S
S
Q
C
S
N
T
E
K
Site 21
S160
K
G
L
S
S
Q
C
S
N
T
E
K
R
L
W
Site 22
T162
L
S
S
Q
C
S
N
T
E
K
R
L
W
V
H
Site 23
S172
R
L
W
V
H
G
L
S
K
E
Q
A
S
A
S
Site 24
S177
G
L
S
K
E
Q
A
S
A
S
G
A
Q
K
G
Site 25
S179
S
K
E
Q
A
S
A
S
G
A
Q
K
G
R
T
Site 26
T186
S
G
A
Q
K
G
R
T
Q
G
G
S
Q
S
S
Site 27
S190
K
G
R
T
Q
G
G
S
Q
S
S
Y
V
L
Q
Site 28
S192
R
T
Q
G
G
S
Q
S
S
Y
V
L
Q
T
E
Site 29
Y194
Q
G
G
S
Q
S
S
Y
V
L
Q
T
E
E
L
Site 30
T210
V
N
K
Q
Q
R
E
T
K
N
S
H
Q
N
K
Site 31
Y220
S
H
Q
N
K
G
H
Y
Q
N
V
V
D
V
R
Site 32
S232
D
V
R
E
E
H
S
S
K
L
Q
T
S
L
H
Site 33
T236
E
H
S
S
K
L
Q
T
S
L
H
P
A
H
Q
Site 34
S237
H
S
S
K
L
Q
T
S
L
H
P
A
H
Q
D
Site 35
T255
H
G
P
K
D
I
F
T
T
Q
D
E
L
L
V
Site 36
Y263
T
Q
D
E
L
L
V
Y
N
K
N
Q
H
Q
T
Site 37
S274
Q
H
Q
T
K
N
L
S
Q
D
Q
E
H
G
R
Site 38
S287
G
R
K
A
H
K
I
S
Y
P
S
S
R
T
E
Site 39
Y288
R
K
A
H
K
I
S
Y
P
S
S
R
T
E
E
Site 40
S290
A
H
K
I
S
Y
P
S
S
R
T
E
E
R
Q
Site 41
S291
H
K
I
S
Y
P
S
S
R
T
E
E
R
Q
L
Site 42
S304
Q
L
H
H
G
E
K
S
V
Q
K
D
V
S
K
Site 43
S310
K
S
V
Q
K
D
V
S
K
G
S
I
S
I
Q
Site 44
S326
E
E
K
I
H
G
K
S
Q
N
Q
V
T
I
H
Site 45
S347
G
H
K
E
N
K
I
S
Y
Q
S
S
S
T
E
Site 46
Y348
H
K
E
N
K
I
S
Y
Q
S
S
S
T
E
E
Site 47
S350
E
N
K
I
S
Y
Q
S
S
S
T
E
E
R
H
Site 48
S351
N
K
I
S
Y
Q
S
S
S
T
E
E
R
H
L
Site 49
S352
K
I
S
Y
Q
S
S
S
T
E
E
R
H
L
N
Site 50
T353
I
S
Y
Q
S
S
S
T
E
E
R
H
L
N
C
Site 51
S370
K
G
I
Q
K
G
V
S
K
G
S
I
S
I
Q
Site 52
S386
E
E
Q
I
H
G
K
S
Q
N
Q
V
R
I
P
Site 53
S394
Q
N
Q
V
R
I
P
S
Q
A
Q
E
Y
G
H
Site 54
S410
E
N
K
I
S
Y
Q
S
S
S
T
E
E
R
R
Site 55
S411
N
K
I
S
Y
Q
S
S
S
T
E
E
R
R
L
Site 56
S412
K
I
S
Y
Q
S
S
S
T
E
E
R
R
L
N
Site 57
T413
I
S
Y
Q
S
S
S
T
E
E
R
R
L
N
S
Site 58
S420
T
E
E
R
R
L
N
S
G
E
K
D
V
Q
K
Site 59
S446
E
E
K
I
H
G
K
S
Q
N
Q
V
T
I
P
Site 60
S454
Q
N
Q
V
T
I
P
S
Q
D
Q
E
H
G
H
Site 61
S467
G
H
K
E
N
K
M
S
Y
Q
S
S
S
T
E
Site 62
Y468
H
K
E
N
K
M
S
Y
Q
S
S
S
T
E
E
Site 63
S471
N
K
M
S
Y
Q
S
S
S
T
E
E
R
R
L
Site 64
S472
K
M
S
Y
Q
S
S
S
T
E
E
R
R
L
N
Site 65
T473
M
S
Y
Q
S
S
S
T
E
E
R
R
L
N
Y
Site 66
Y480
T
E
E
R
R
L
N
Y
G
G
K
S
T
Q
K
Site 67
T485
L
N
Y
G
G
K
S
T
Q
K
D
V
S
Q
S
Site 68
S490
K
S
T
Q
K
D
V
S
Q
S
S
I
S
F
Q
Site 69
S495
D
V
S
Q
S
S
I
S
F
Q
I
E
K
L
V
Site 70
S506
E
K
L
V
E
G
K
S
Q
I
Q
T
P
N
P
Site 71
T510
E
G
K
S
Q
I
Q
T
P
N
P
N
Q
D
Q
Site 72
S527
G
Q
N
A
K
G
K
S
G
Q
S
A
D
S
K
Site 73
S533
K
S
G
Q
S
A
D
S
K
Q
D
L
L
S
H
Site 74
S539
D
S
K
Q
D
L
L
S
H
E
Q
K
G
R
Y
Site 75
Y546
S
H
E
Q
K
G
R
Y
K
Q
E
S
S
E
S
Site 76
S550
K
G
R
Y
K
Q
E
S
S
E
S
H
N
I
V
Site 77
T570
V
A
Q
D
D
H
L
T
Q
Q
Y
N
E
D
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation