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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF45
Full Name:
Zinc finger protein 45
Alias:
BRC1744;Zinc finger protein 13;Zinc finger protein KOX5
Type:
Mass (Da):
78242
Number AA:
682
UniProt ID:
Q02386
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y33
D
L
A
Q
R
K
L
Y
R
D
V
M
L
E
N
Site 2
S46
E
N
F
R
N
V
V
S
V
G
H
Q
S
T
P
Site 3
T52
V
S
V
G
H
Q
S
T
P
D
G
L
P
Q
L
Site 4
S77
M
A
T
Q
R
D
N
S
S
G
A
K
N
L
K
Site 5
Y96
L
Q
E
V
G
L
R
Y
L
P
H
E
E
L
F
Site 6
Y118
I
T
R
E
L
I
K
Y
Q
D
S
V
V
N
I
Site 7
S121
E
L
I
K
Y
Q
D
S
V
V
N
I
Q
R
T
Site 8
Y140
E
K
R
D
D
L
H
Y
K
D
E
G
F
S
N
Site 9
S150
E
G
F
S
N
Q
S
S
H
L
Q
V
H
R
V
Site 10
T159
L
Q
V
H
R
V
H
T
G
E
K
P
Y
K
G
Site 11
S172
K
G
E
H
C
V
K
S
F
S
W
S
S
H
L
Site 12
S205
D
N
A
F
R
R
F
S
S
L
Q
A
H
Q
R
Site 13
S206
N
A
F
R
R
F
S
S
L
Q
A
H
Q
R
V
Site 14
S215
Q
A
H
Q
R
V
H
S
R
A
K
S
Y
T
N
Site 15
S219
R
V
H
S
R
A
K
S
Y
T
N
D
A
S
Y
Site 16
T221
H
S
R
A
K
S
Y
T
N
D
A
S
Y
R
S
Site 17
S225
K
S
Y
T
N
D
A
S
Y
R
S
F
S
Q
R
Site 18
Y226
S
Y
T
N
D
A
S
Y
R
S
F
S
Q
R
S
Site 19
S228
T
N
D
A
S
Y
R
S
F
S
Q
R
S
H
L
Site 20
S230
D
A
S
Y
R
S
F
S
Q
R
S
H
L
P
H
Site 21
T243
P
H
H
Q
R
V
P
T
G
E
N
P
Y
K
Y
Site 22
Y250
T
G
E
N
P
Y
K
Y
E
E
C
G
R
N
V
Site 23
S260
C
G
R
N
V
G
K
S
S
H
C
Q
A
P
L
Site 24
S261
G
R
N
V
G
K
S
S
H
C
Q
A
P
L
I
Site 25
T271
Q
A
P
L
I
V
H
T
G
E
K
P
Y
K
C
Site 26
S286
E
E
C
G
V
G
F
S
Q
R
S
Y
L
Q
V
Site 27
Y290
V
G
F
S
Q
R
S
Y
L
Q
V
H
L
K
V
Site 28
S312
K
C
E
E
C
G
K
S
F
S
W
R
S
R
L
Site 29
S314
E
E
C
G
K
S
F
S
W
R
S
R
L
Q
A
Site 30
T327
Q
A
H
E
R
I
H
T
G
E
K
P
Y
K
C
Site 31
S340
K
C
N
A
C
G
K
S
F
S
Y
S
S
H
L
Site 32
S342
N
A
C
G
K
S
F
S
Y
S
S
H
L
N
I
Site 33
S345
G
K
S
F
S
Y
S
S
H
L
N
I
H
C
R
Site 34
T355
N
I
H
C
R
I
H
T
G
E
K
P
Y
K
C
Site 35
S370
E
E
C
G
K
G
F
S
V
G
S
H
L
Q
A
Site 36
S381
H
L
Q
A
H
Q
I
S
H
T
G
E
K
P
Y
Site 37
Y388
S
H
T
G
E
K
P
Y
K
C
E
E
C
G
K
Site 38
S401
G
K
G
F
C
R
A
S
N
L
L
D
H
Q
R
Site 39
T411
L
D
H
Q
R
G
H
T
G
E
K
P
Y
Q
C
Site 40
Y416
G
H
T
G
E
K
P
Y
Q
C
D
A
C
G
K
Site 41
S426
D
A
C
G
K
G
F
S
R
S
S
D
F
N
I
Site 42
S428
C
G
K
G
F
S
R
S
S
D
F
N
I
H
F
Site 43
S429
G
K
G
F
S
R
S
S
D
F
N
I
H
F
R
Site 44
T439
N
I
H
F
R
V
H
T
G
E
K
P
Y
K
C
Site 45
S454
E
E
C
G
K
G
F
S
Q
A
S
N
L
L
A
Site 46
T467
L
A
H
Q
R
G
H
T
G
E
K
P
Y
K
C
Site 47
Y472
G
H
T
G
E
K
P
Y
K
C
G
T
C
G
K
Site 48
T476
E
K
P
Y
K
C
G
T
C
G
K
G
F
S
R
Site 49
S482
G
T
C
G
K
G
F
S
R
S
S
D
L
N
V
Site 50
S484
C
G
K
G
F
S
R
S
S
D
L
N
V
H
C
Site 51
S485
G
K
G
F
S
R
S
S
D
L
N
V
H
C
R
Site 52
T495
N
V
H
C
R
I
H
T
G
E
K
P
Y
K
C
Site 53
S510
E
R
C
G
K
A
F
S
Q
F
S
S
L
Q
V
Site 54
S514
K
A
F
S
Q
F
S
S
L
Q
V
H
Q
R
V
Site 55
T523
Q
V
H
Q
R
V
H
T
G
E
K
P
Y
Q
C
Site 56
Y528
V
H
T
G
E
K
P
Y
Q
C
A
E
C
G
K
Site 57
S538
A
E
C
G
K
G
F
S
V
G
S
Q
L
Q
A
Site 58
S541
G
K
G
F
S
V
G
S
Q
L
Q
A
H
Q
R
Site 59
T551
Q
A
H
Q
R
C
H
T
G
E
K
P
Y
Q
C
Site 60
Y556
C
H
T
G
E
K
P
Y
Q
C
E
E
C
G
K
Site 61
S569
G
K
G
F
C
R
A
S
N
F
L
A
H
R
G
Site 62
T579
L
A
H
R
G
V
H
T
G
E
K
P
Y
R
C
Site 63
S597
G
K
R
F
R
Q
R
S
Y
L
Q
A
H
Q
R
Site 64
Y598
K
R
F
R
Q
R
S
Y
L
Q
A
H
Q
R
V
Site 65
T607
Q
A
H
Q
R
V
H
T
G
E
R
P
Y
K
C
Site 66
Y612
V
H
T
G
E
R
P
Y
K
C
E
E
C
G
K
Site 67
S622
E
E
C
G
K
V
F
S
W
S
S
Y
L
Q
A
Site 68
S625
G
K
V
F
S
W
S
S
Y
L
Q
A
H
Q
R
Site 69
Y626
K
V
F
S
W
S
S
Y
L
Q
A
H
Q
R
V
Site 70
T635
Q
A
H
Q
R
V
H
T
G
E
K
P
Y
K
C
Site 71
S650
E
E
C
G
K
G
F
S
W
S
S
S
L
I
I
Site 72
S652
C
G
K
G
F
S
W
S
S
S
L
I
I
H
Q
Site 73
S654
K
G
F
S
W
S
S
S
L
I
I
H
Q
R
V
Site 74
S673
E
G
D
K
D
F
P
S
S
E
D
S
H
R
K
Site 75
S674
G
D
K
D
F
P
S
S
E
D
S
H
R
K
T
Site 76
S677
D
F
P
S
S
E
D
S
H
R
K
T
R
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation