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Updated November 2019
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Protein Info
Short Name:
COL7A1
Full Name:
Collagen alpha-1(VII) chain
Alias:
Long-chain collagen
Type:
Mass (Da):
295220
Number AA:
2944
UniProt ID:
Q02388
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T30
A
Q
H
R
E
R
V
T
C
T
R
L
Y
A
A
Site 2
Y35
R
V
T
C
T
R
L
Y
A
A
D
I
V
F
L
Site 3
S47
V
F
L
L
D
G
S
S
S
I
G
R
S
N
F
Site 4
S48
F
L
L
D
G
S
S
S
I
G
R
S
N
F
R
Site 5
S52
G
S
S
S
I
G
R
S
N
F
R
E
V
R
S
Site 6
T81
A
Q
G
V
R
F
A
T
V
Q
Y
S
D
D
P
Site 7
S85
R
F
A
T
V
Q
Y
S
D
D
P
R
T
E
F
Site 8
T90
Q
Y
S
D
D
P
R
T
E
F
G
L
D
A
L
Site 9
S111
I
R
A
I
R
E
L
S
Y
K
G
G
N
T
R
Site 10
T117
L
S
Y
K
G
G
N
T
R
T
G
A
A
I
L
Site 11
T158
K
S
Q
D
L
V
D
T
A
A
Q
R
L
K
G
Site 12
S188
E
E
L
K
R
V
A
S
Q
P
T
S
D
F
F
Site 13
T225
T
A
G
G
V
P
V
T
R
P
P
D
D
S
T
Site 14
S231
V
T
R
P
P
D
D
S
T
S
A
P
R
D
L
Site 15
T232
T
R
P
P
D
D
S
T
S
A
P
R
D
L
V
Site 16
S233
R
P
P
D
D
S
T
S
A
P
R
D
L
V
L
Site 17
S241
A
P
R
D
L
V
L
S
E
P
S
S
Q
S
L
Site 18
S245
L
V
L
S
E
P
S
S
Q
S
L
R
V
Q
W
Site 19
S247
L
S
E
P
S
S
Q
S
L
R
V
Q
W
T
A
Site 20
T260
T
A
A
S
G
P
V
T
G
Y
K
V
Q
Y
T
Site 21
T267
T
G
Y
K
V
Q
Y
T
P
L
T
G
L
G
Q
Site 22
T270
K
V
Q
Y
T
P
L
T
G
L
G
Q
P
L
P
Site 23
S278
G
L
G
Q
P
L
P
S
E
R
Q
E
V
N
V
Site 24
S291
N
V
P
A
G
E
T
S
V
R
L
R
G
L
R
Site 25
T326
V
S
G
T
A
R
T
T
A
L
E
G
P
E
L
Site 26
T359
G
A
T
G
Y
R
V
T
W
R
V
L
S
G
G
Site 27
S364
R
V
T
W
R
V
L
S
G
G
P
T
Q
Q
Q
Site 28
T368
R
V
L
S
G
G
P
T
Q
Q
Q
E
L
G
P
Site 29
Y391
D
L
E
P
G
T
D
Y
E
V
T
V
S
T
L
Site 30
T394
P
G
T
D
Y
E
V
T
V
S
T
L
F
G
R
Site 31
S402
V
S
T
L
F
G
R
S
V
G
P
A
T
S
L
Site 32
S408
R
S
V
G
P
A
T
S
L
M
A
R
T
D
A
Site 33
S416
L
M
A
R
T
D
A
S
V
E
Q
T
L
R
P
Site 34
Y444
L
V
P
E
A
R
G
Y
R
L
E
W
R
R
E
Site 35
T452
R
L
E
W
R
R
E
T
G
L
E
P
P
Q
K
Site 36
Y469
L
P
S
D
V
T
R
Y
Q
L
D
G
L
Q
P
Site 37
T478
L
D
G
L
Q
P
G
T
E
Y
R
L
T
L
Y
Site 38
T483
P
G
T
E
Y
R
L
T
L
Y
T
L
L
E
G
Site 39
Y485
T
E
Y
R
L
T
L
Y
T
L
L
E
G
H
E
Site 40
T486
E
Y
R
L
T
L
Y
T
L
L
E
G
H
E
V
Site 41
T498
H
E
V
A
T
P
A
T
V
V
P
T
G
P
E
Site 42
S509
T
G
P
E
L
P
V
S
P
V
T
D
L
Q
A
Site 43
S527
P
G
Q
R
V
R
V
S
W
S
P
V
P
G
A
Site 44
S529
Q
R
V
R
V
S
W
S
P
V
P
G
A
T
Q
Site 45
S543
Q
Y
R
I
I
V
R
S
T
Q
G
V
E
R
T
Site 46
T544
Y
R
I
I
V
R
S
T
Q
G
V
E
R
T
L
Site 47
S556
R
T
L
V
L
P
G
S
Q
T
A
F
D
L
D
Site 48
S570
D
D
V
Q
A
G
L
S
Y
T
V
R
V
S
A
Site 49
S576
L
S
Y
T
V
R
V
S
A
R
V
G
P
R
E
Site 50
S585
R
V
G
P
R
E
G
S
A
S
V
L
T
V
R
Site 51
S587
G
P
R
E
G
S
A
S
V
L
T
V
R
R
E
Site 52
T590
E
G
S
A
S
V
L
T
V
R
R
E
P
E
T
Site 53
T597
T
V
R
R
E
P
E
T
P
L
A
V
P
G
L
Site 54
S625
W
G
P
V
P
G
A
S
G
F
R
I
S
W
S
Site 55
S630
G
A
S
G
F
R
I
S
W
S
T
G
S
G
P
Site 56
S632
S
G
F
R
I
S
W
S
T
G
S
G
P
E
S
Site 57
T633
G
F
R
I
S
W
S
T
G
S
G
P
E
S
S
Site 58
S635
R
I
S
W
S
T
G
S
G
P
E
S
S
Q
T
Site 59
S639
S
T
G
S
G
P
E
S
S
Q
T
L
P
P
D
Site 60
S640
T
G
S
G
P
E
S
S
Q
T
L
P
P
D
S
Site 61
T642
S
G
P
E
S
S
Q
T
L
P
P
D
S
T
A
Site 62
S647
S
Q
T
L
P
P
D
S
T
A
T
D
I
T
G
Site 63
T691
D
P
L
G
P
V
R
T
V
H
V
T
Q
A
S
Site 64
T695
P
V
R
T
V
H
V
T
Q
A
S
S
S
S
V
Site 65
S700
H
V
T
Q
A
S
S
S
S
V
T
I
T
W
T
Site 66
S701
V
T
Q
A
S
S
S
S
V
T
I
T
W
T
R
Site 67
T703
Q
A
S
S
S
S
V
T
I
T
W
T
R
V
P
Site 68
T705
S
S
S
S
V
T
I
T
W
T
R
V
P
G
A
Site 69
Y715
R
V
P
G
A
T
G
Y
R
V
S
W
H
S
A
Site 70
S718
G
A
T
G
Y
R
V
S
W
H
S
A
H
G
P
Site 71
S721
G
Y
R
V
S
W
H
S
A
H
G
P
E
K
S
Site 72
S728
S
A
H
G
P
E
K
S
Q
L
V
S
G
E
A
Site 73
S732
P
E
K
S
Q
L
V
S
G
E
A
T
V
A
E
Site 74
T747
L
D
G
L
E
P
D
T
E
Y
T
V
H
V
R
Site 75
Y749
G
L
E
P
D
T
E
Y
T
V
H
V
R
A
H
Site 76
T750
L
E
P
D
T
E
Y
T
V
H
V
R
A
H
V
Site 77
S780
P
E
P
V
G
R
V
S
R
L
Q
I
L
N
A
Site 78
S812
Y
R
L
A
W
G
R
S
E
G
G
P
M
R
H
Site 79
S828
I
L
P
G
N
T
D
S
A
E
I
R
G
L
E
Site 80
S839
R
G
L
E
G
G
V
S
Y
S
V
R
V
T
A
Site 81
S857
D
R
E
G
T
P
V
S
I
V
V
T
T
P
P
Site 82
S882
V
V
Q
R
G
E
H
S
L
R
L
R
W
E
P
Site 83
S917
R
V
L
G
P
E
L
S
S
Y
H
L
D
G
L
Site 84
Y919
L
G
P
E
L
S
S
Y
H
L
D
G
L
E
P
Site 85
T928
L
D
G
L
E
P
A
T
Q
Y
R
V
R
L
S
Site 86
Y930
G
L
E
P
A
T
Q
Y
R
V
R
L
S
V
L
Site 87
S935
T
Q
Y
R
V
R
L
S
V
L
G
P
A
G
E
Site 88
T949
E
G
P
S
A
E
V
T
A
R
T
E
S
P
R
Site 89
S954
E
V
T
A
R
T
E
S
P
R
V
P
S
I
E
Site 90
S959
T
E
S
P
R
V
P
S
I
E
L
R
V
V
D
Site 91
T977
D
S
V
T
L
A
W
T
P
V
S
R
A
S
S
Site 92
S983
W
T
P
V
S
R
A
S
S
Y
I
L
S
W
R
Site 93
S984
T
P
V
S
R
A
S
S
Y
I
L
S
W
R
P
Site 94
S988
R
A
S
S
Y
I
L
S
W
R
P
L
R
G
P
Site 95
S1002
P
G
Q
E
V
P
G
S
P
Q
T
L
P
G
I
Site 96
T1005
E
V
P
G
S
P
Q
T
L
P
G
I
S
S
S
Site 97
S1011
Q
T
L
P
G
I
S
S
S
Q
R
V
T
G
L
Site 98
S1012
T
L
P
G
I
S
S
S
Q
R
V
T
G
L
E
Site 99
T1016
I
S
S
S
Q
R
V
T
G
L
E
P
G
V
S
Site 100
S1041
G
V
R
G
P
E
A
S
V
T
Q
T
P
V
C
Site 101
T1043
R
G
P
E
A
S
V
T
Q
T
P
V
C
P
R
Site 102
T1045
P
E
A
S
V
T
Q
T
P
V
C
P
R
G
L
Site 103
S1097
A
V
Q
V
G
L
L
S
Y
S
H
R
P
S
P
Site 104
S1099
Q
V
G
L
L
S
Y
S
H
R
P
S
P
L
F
Site 105
S1103
L
S
Y
S
H
R
P
S
P
L
F
P
L
N
G
Site 106
Y1126
Q
R
I
R
D
M
P
Y
M
D
P
S
G
N
N
Site 107
S1130
D
M
P
Y
M
D
P
S
G
N
N
L
G
T
A
Site 108
T1136
P
S
G
N
N
L
G
T
A
V
V
T
A
H
R
Site 109
S1175
P
L
R
G
D
I
F
S
P
I
R
E
A
Q
A
Site 110
T1212
P
G
M
D
S
V
Q
T
F
F
A
V
D
D
G
Site 111
S1221
F
A
V
D
D
G
P
S
L
D
Q
A
V
S
G
Site 112
S1237
A
T
A
L
C
Q
A
S
F
T
T
Q
P
R
P
Site 113
T1239
A
L
C
Q
A
S
F
T
T
Q
P
R
P
E
P
Site 114
Y1250
R
P
E
P
C
P
V
Y
C
P
K
G
Q
K
G
Site 115
T1280
D
P
G
L
P
G
R
T
G
A
P
G
P
Q
G
Site 116
S1291
G
P
Q
G
P
P
G
S
A
T
A
K
G
E
R
Site 117
S1309
G
A
D
G
R
P
G
S
P
G
R
A
G
N
P
Site 118
T1318
G
R
A
G
N
P
G
T
P
G
A
P
G
L
K
Site 119
S1327
G
A
P
G
L
K
G
S
P
G
L
P
G
P
R
Site 120
S1373
R
K
G
D
P
G
P
S
G
P
P
G
P
R
G
Site 121
T1396
G
P
P
G
L
P
G
T
A
M
K
G
D
K
G
Site 122
S1431
G
L
P
G
L
P
G
S
P
G
P
Q
G
P
V
Site 123
S1450
K
K
G
E
K
G
D
S
E
D
G
A
P
G
L
Site 124
S1463
G
L
P
G
Q
P
G
S
P
G
E
Q
G
P
R
Site 125
T1568
P
A
G
P
R
G
A
T
G
V
Q
G
E
R
G
Site 126
T1600
D
R
G
P
I
G
L
T
G
R
A
G
P
P
G
Site 127
S1609
R
A
G
P
P
G
D
S
G
P
P
G
E
K
G
Site 128
S1686
G
E
D
G
R
N
G
S
P
G
S
S
G
P
K
Site 129
S1689
G
R
N
G
S
P
G
S
S
G
P
K
G
D
R
Site 130
S1690
R
N
G
S
P
G
S
S
G
P
K
G
D
R
G
Site 131
T1711
P
P
G
R
L
V
D
T
G
P
G
A
R
E
K
Site 132
S1781
P
P
G
L
D
G
R
S
G
L
D
G
K
P
G
Site 133
S1823
E
Q
G
L
P
G
P
S
G
P
P
G
L
P
G
Site 134
S1862
R
K
G
E
K
G
D
S
G
A
S
G
R
E
G
Site 135
S1865
E
K
G
D
S
G
A
S
G
R
E
G
R
D
G
Site 136
T1918
P
K
G
D
R
G
E
T
G
S
K
G
E
Q
G
Site 137
S1920
G
D
R
G
E
T
G
S
K
G
E
Q
G
L
P
Site 138
S1938
G
L
R
G
E
P
G
S
V
P
N
V
D
R
L
Site 139
T1962
A
L
R
E
I
V
E
T
W
D
E
S
S
G
S
Site 140
S1969
T
W
D
E
S
S
G
S
F
L
P
V
P
E
R
Site 141
S1984
R
R
G
P
K
G
D
S
G
E
Q
G
P
P
G
Site 142
T2083
G
P
P
G
L
P
G
T
P
G
P
P
G
P
P
Site 143
S2095
G
P
P
G
P
K
V
S
V
D
E
P
G
P
G
Site 144
S2104
D
E
P
G
P
G
L
S
G
E
Q
G
P
P
G
Site 145
S2121
G
A
K
G
E
P
G
S
N
G
D
Q
G
P
K
Site 146
T2212
L
K
G
E
P
G
E
T
G
P
P
G
R
G
L
Site 147
T2220
G
P
P
G
R
G
L
T
G
P
T
G
A
V
G
Site 148
S2235
L
P
G
P
P
G
P
S
G
L
V
G
P
Q
G
Site 149
S2265
A
P
G
R
D
G
A
S
G
K
D
G
D
R
G
Site 150
S2273
G
K
D
G
D
R
G
S
P
G
V
P
G
S
P
Site 151
S2279
G
S
P
G
V
P
G
S
P
G
L
P
G
P
V
Site 152
T2295
P
K
G
E
P
G
P
T
G
A
P
G
Q
A
V
Site 153
S2378
P
G
V
G
V
P
G
S
P
G
P
P
G
P
P
Site 154
S2421
E
M
G
Q
P
G
P
S
G
E
R
G
L
A
G
Site 155
S2447
G
P
P
G
P
P
G
S
V
G
P
P
G
A
S
Site 156
T2495
Q
E
G
P
R
G
L
T
G
P
P
G
S
R
G
Site 157
S2500
G
L
T
G
P
P
G
S
R
G
E
R
G
E
K
Site 158
S2512
G
E
K
G
D
V
G
S
A
G
L
K
G
D
K
Site 159
S2522
L
K
G
D
K
G
D
S
A
V
I
L
G
P
P
Site 160
S2564
G
D
P
G
D
K
G
S
K
G
E
P
G
D
K
Site 161
S2573
G
E
P
G
D
K
G
S
A
G
L
P
G
L
R
Site 162
S2600
G
I
P
G
D
P
G
S
P
G
K
D
G
V
P
Site 163
S2670
E
P
G
V
P
G
Q
S
G
A
P
G
K
E
G
Site 164
T2705
G
E
K
G
E
R
G
T
P
G
I
G
G
F
P
Site 165
S2715
I
G
G
F
P
G
P
S
G
N
D
G
S
A
G
Site 166
S2720
G
P
S
G
N
D
G
S
A
G
P
P
G
P
P
Site 167
S2729
G
P
P
G
P
P
G
S
V
G
P
R
G
P
E
Site 168
T2786
E
K
G
E
A
A
L
T
E
D
D
I
R
G
F
Site 169
S2811
C
Q
G
Q
F
I
A
S
G
S
R
P
L
P
S
Site 170
S2813
G
Q
F
I
A
S
G
S
R
P
L
P
S
Y
A
Site 171
S2818
S
G
S
R
P
L
P
S
Y
A
A
D
T
A
G
Site 172
Y2819
G
S
R
P
L
P
S
Y
A
A
D
T
A
G
S
Site 173
T2823
L
P
S
Y
A
A
D
T
A
G
S
Q
L
H
A
Site 174
S2837
A
V
P
V
L
R
V
S
H
A
E
E
E
E
R
Site 175
Y2852
V
P
P
E
D
D
E
Y
S
E
Y
S
E
Y
S
Site 176
S2853
P
P
E
D
D
E
Y
S
E
Y
S
E
Y
S
V
Site 177
Y2855
E
D
D
E
Y
S
E
Y
S
E
Y
S
V
E
E
Site 178
S2856
D
D
E
Y
S
E
Y
S
E
Y
S
V
E
E
Y
Site 179
Y2858
E
Y
S
E
Y
S
E
Y
S
V
E
E
Y
Q
D
Site 180
S2859
Y
S
E
Y
S
E
Y
S
V
E
E
Y
Q
D
P
Site 181
Y2863
S
E
Y
S
V
E
E
Y
Q
D
P
E
A
P
W
Site 182
S2872
D
P
E
A
P
W
D
S
D
D
P
C
S
L
P
Site 183
S2877
W
D
S
D
D
P
C
S
L
P
L
D
E
G
S
Site 184
S2884
S
L
P
L
D
E
G
S
C
T
A
Y
T
L
R
Site 185
T2886
P
L
D
E
G
S
C
T
A
Y
T
L
R
W
Y
Site 186
Y2888
D
E
G
S
C
T
A
Y
T
L
R
W
Y
H
R
Site 187
Y2893
T
A
Y
T
L
R
W
Y
H
R
A
V
T
G
S
Site 188
T2898
R
W
Y
H
R
A
V
T
G
S
T
E
A
C
H
Site 189
T2921
G
N
A
N
R
F
G
T
R
E
A
C
E
R
R
Site 190
S2936
C
P
P
R
V
V
Q
S
Q
G
T
G
T
A
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation