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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SP3
Full Name:
Transcription factor Sp3
Alias:
SPR-2
Type:
Intracellular, Nucleus protein
Mass (Da):
81925
Number AA:
781
UniProt ID:
Q02447
International Prot ID:
IPI00025807
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005634
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0016563
GO:0016564
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
GO:0002376
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y33
G
G
G
G
H
G
E
Y
L
Q
Q
Q
Q
Q
H
Site 2
S57
A
A
Q
D
T
Q
P
S
P
L
A
L
L
A
A
Site 3
S73
C
S
K
I
G
P
P
S
P
G
D
D
E
E
E
Site 4
S113
P
N
R
W
E
V
L
S
A
T
P
T
T
I
K
Site 5
T115
R
W
E
V
L
S
A
T
P
T
T
I
K
D
E
Site 6
T117
E
V
L
S
A
T
P
T
T
I
K
D
E
A
G
Site 7
S131
G
N
L
V
Q
I
P
S
A
A
T
S
S
G
Q
Site 8
S135
Q
I
P
S
A
A
T
S
S
G
Q
Y
V
L
P
Site 9
S153
L
Q
N
Q
Q
I
F
S
V
A
P
G
S
D
S
Site 10
S160
S
V
A
P
G
S
D
S
S
N
G
T
V
S
S
Site 11
S161
V
A
P
G
S
D
S
S
N
G
T
V
S
S
V
Site 12
T164
G
S
D
S
S
N
G
T
V
S
S
V
Q
Y
Q
Site 13
S167
S
S
N
G
T
V
S
S
V
Q
Y
Q
V
I
P
Site 14
Y170
G
T
V
S
S
V
Q
Y
Q
V
I
P
Q
I
Q
Site 15
S191
V
Q
I
G
F
T
G
S
S
D
N
G
G
I
N
Site 16
S192
Q
I
G
F
T
G
S
S
D
N
G
G
I
N
Q
Site 17
S202
G
G
I
N
Q
E
S
S
Q
I
Q
I
I
P
G
Site 18
S217
S
N
Q
T
L
L
A
S
G
T
P
S
A
N
I
Site 19
T219
Q
T
L
L
A
S
G
T
P
S
A
N
I
Q
N
Site 20
S244
Q
G
V
A
I
G
G
S
S
F
P
G
Q
T
Q
Site 21
S280
D
L
D
S
L
G
L
S
G
S
S
Q
T
M
T
Site 22
S282
D
S
L
G
L
S
G
S
S
Q
T
M
T
A
G
Site 23
T287
S
G
S
S
Q
T
M
T
A
G
I
N
A
D
G
Site 24
S305
N
T
G
Q
A
M
D
S
S
D
N
S
E
R
T
Site 25
S306
T
G
Q
A
M
D
S
S
D
N
S
E
R
T
G
Site 26
S309
A
M
D
S
S
D
N
S
E
R
T
G
E
R
V
Site 27
S317
E
R
T
G
E
R
V
S
P
D
I
N
E
T
N
Site 28
T327
I
N
E
T
N
T
D
T
D
L
F
V
P
T
S
Site 29
T333
D
T
D
L
F
V
P
T
S
S
S
S
Q
L
P
Site 30
T353
T
G
I
L
Q
Q
N
T
N
S
L
T
T
S
S
Site 31
S355
I
L
Q
Q
N
T
N
S
L
T
T
S
S
G
Q
Site 32
T357
Q
Q
N
T
N
S
L
T
T
S
S
G
Q
V
H
Site 33
S359
N
T
N
S
L
T
T
S
S
G
Q
V
H
S
S
Site 34
S360
T
N
S
L
T
T
S
S
G
Q
V
H
S
S
D
Site 35
Y372
S
S
D
L
Q
G
N
Y
I
Q
S
P
V
S
E
Site 36
S375
L
Q
G
N
Y
I
Q
S
P
V
S
E
E
T
Q
Site 37
S378
N
Y
I
Q
S
P
V
S
E
E
T
Q
A
Q
N
Site 38
S403
Q
H
L
Q
L
Q
E
S
Q
Q
P
T
S
Q
A
Site 39
S408
Q
E
S
Q
Q
P
T
S
Q
A
Q
I
V
Q
G
Site 40
S427
T
I
H
G
V
Q
A
S
G
Q
N
I
S
Q
Q
Site 41
T462
V
T
P
S
G
Q
V
T
W
Q
T
F
Q
V
Q
Site 42
S514
T
S
T
P
V
S
L
S
T
G
Q
L
P
N
L
Site 43
T523
G
Q
L
P
N
L
Q
T
V
T
V
N
S
I
D
Site 44
S544
H
P
G
E
N
A
D
S
P
A
D
I
R
I
K
Site 45
S563
D
P
E
E
W
Q
L
S
G
D
S
T
L
N
T
Site 46
S566
E
W
Q
L
S
G
D
S
T
L
N
T
N
D
L
Site 47
T567
W
Q
L
S
G
D
S
T
L
N
T
N
D
L
T
Site 48
T570
S
G
D
S
T
L
N
T
N
D
L
T
H
L
R
Site 49
T574
T
L
N
T
N
D
L
T
H
L
R
V
Q
V
V
Site 50
T601
R
L
R
R
V
A
C
T
C
P
N
C
K
E
G
Site 51
T613
K
E
G
G
G
R
G
T
N
L
G
K
K
K
Q
Site 52
Y632
I
P
G
C
G
K
V
Y
G
K
T
S
H
L
R
Site 53
S636
G
K
V
Y
G
K
T
S
H
L
R
A
H
L
R
Site 54
S646
R
A
H
L
R
W
H
S
G
E
R
P
F
V
C
Site 55
T663
M
Y
C
G
K
R
F
T
R
S
D
E
L
Q
R
Site 56
S665
C
G
K
R
F
T
R
S
D
E
L
Q
R
H
R
Site 57
T674
E
L
Q
R
H
R
R
T
H
T
G
E
K
K
F
Site 58
T676
Q
R
H
R
R
T
H
T
G
E
K
K
F
V
C
Site 59
S712
N
K
K
G
I
H
S
S
S
T
V
L
A
S
V
Site 60
S713
K
K
G
I
H
S
S
S
T
V
L
A
S
V
E
Site 61
T726
V
E
A
A
R
D
D
T
L
I
T
A
G
G
T
Site 62
T753
S
G
I
G
T
V
N
T
S
A
T
S
N
Q
D
Site 63
T763
T
S
N
Q
D
I
L
T
N
T
E
I
P
L
Q
Site 64
S775
P
L
Q
L
V
T
V
S
G
N
E
T
M
E
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation