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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DSC2
Full Name:
Desmocollin-2
Alias:
CDHF2; Desmocollin 2; Desmocollin-3; Desmosomal glycoprotein II and III; DSC3; DSC3, Desmocollin 2A/2B precursor
Type:
Adhesion protein
Mass (Da):
99962
Number AA:
901
UniProt ID:
Q02487
International Prot ID:
IPI00218928
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000267
GO:0005624
GO:0005626
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005509
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
GO:0007156
GO:0009987
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
E
A
A
R
P
S
G
S
W
N
G
A
L
Site 2
S9
E
A
A
R
P
S
G
S
W
N
G
A
L
C
R
Site 3
T36
S
D
A
C
K
N
V
T
L
H
V
P
S
K
L
Site 4
S78
F
Q
I
L
E
D
G
S
V
Y
T
T
N
T
I
Site 5
T82
E
D
G
S
V
Y
T
T
N
T
I
L
L
S
S
Site 6
T84
G
S
V
Y
T
T
N
T
I
L
L
S
S
E
K
Site 7
S88
T
T
N
T
I
L
L
S
S
E
K
R
S
F
T
Site 8
S89
T
N
T
I
L
L
S
S
E
K
R
S
F
T
I
Site 9
S93
L
L
S
S
E
K
R
S
F
T
I
L
L
S
N
Site 10
T95
S
S
E
K
R
S
F
T
I
L
L
S
N
T
E
Site 11
S99
R
S
F
T
I
L
L
S
N
T
E
N
Q
E
K
Site 12
T125
K
V
L
K
K
R
H
T
K
E
K
V
L
R
R
Site 13
T524
W
V
T
I
D
E
N
T
G
S
I
K
V
F
R
Site 14
S526
T
I
D
E
N
T
G
S
I
K
V
F
R
S
L
Site 15
S719
F
T
L
V
C
G
A
S
G
T
S
K
Q
P
K
Site 16
T742
Q
N
L
I
V
S
N
T
E
A
P
G
D
D
K
Site 17
Y751
A
P
G
D
D
K
V
Y
S
A
N
G
F
T
T
Site 18
S752
P
G
D
D
K
V
Y
S
A
N
G
F
T
T
Q
Site 19
T760
A
N
G
F
T
T
Q
T
V
G
A
S
A
Q
G
Site 20
S774
G
V
C
G
T
V
G
S
G
I
K
N
G
G
Q
Site 21
S794
V
K
G
G
H
Q
T
S
E
S
C
R
G
A
G
Site 22
S796
G
G
H
Q
T
S
E
S
C
R
G
A
G
H
H
Site 23
T805
R
G
A
G
H
H
H
T
L
D
S
C
R
G
G
Site 24
T814
D
S
C
R
G
G
H
T
E
V
D
N
C
R
Y
Site 25
Y821
T
E
V
D
N
C
R
Y
T
Y
S
E
W
H
S
Site 26
T822
E
V
D
N
C
R
Y
T
Y
S
E
W
H
S
F
Site 27
Y823
V
D
N
C
R
Y
T
Y
S
E
W
H
S
F
T
Site 28
S824
D
N
C
R
Y
T
Y
S
E
W
H
S
F
T
Q
Site 29
S828
Y
T
Y
S
E
W
H
S
F
T
Q
P
R
L
G
Site 30
T830
Y
S
E
W
H
S
F
T
Q
P
R
L
G
E
K
Site 31
Y839
P
R
L
G
E
K
V
Y
L
C
N
Q
D
E
N
Site 32
Y853
N
H
K
H
A
Q
D
Y
V
L
T
Y
N
Y
E
Site 33
Y857
A
Q
D
Y
V
L
T
Y
N
Y
E
G
R
G
S
Site 34
Y859
D
Y
V
L
T
Y
N
Y
E
G
R
G
S
V
A
Site 35
S864
Y
N
Y
E
G
R
G
S
V
A
G
S
V
G
C
Site 36
S868
G
R
G
S
V
A
G
S
V
G
C
C
S
E
R
Site 37
S873
A
G
S
V
G
C
C
S
E
R
Q
E
E
D
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation