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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PAX5
Full Name:
Paired box protein Pax-5
Alias:
B-cell-specific transcription factor; BSAP; Paired box gene 5 (B-cell lineage specific activator protein)
Type:
Nucleus protein
Mass (Da):
42149
Number AA:
391
UniProt ID:
Q02548
International Prot ID:
IPI00026209
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
PhosphoSite+
KinaseNET
Biological Process:
GO:0030154
GO:0006959
GO:0007399
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y7
_
M
D
L
E
K
N
Y
P
T
P
R
T
S
R
Site 2
T9
D
L
E
K
N
Y
P
T
P
R
T
S
R
T
G
Site 3
T12
K
N
Y
P
T
P
R
T
S
R
T
G
H
G
G
Site 4
S13
N
Y
P
T
P
R
T
S
R
T
G
H
G
G
V
Site 5
S55
G
V
R
P
C
D
I
S
R
Q
L
R
V
S
H
Site 6
S61
I
S
R
Q
L
R
V
S
H
G
C
V
S
K
I
Site 7
Y72
V
S
K
I
L
G
R
Y
Y
E
T
G
S
I
K
Site 8
Y73
S
K
I
L
G
R
Y
Y
E
T
G
S
I
K
P
Site 9
S77
G
R
Y
Y
E
T
G
S
I
K
P
G
V
I
G
Site 10
T92
G
S
K
P
K
V
A
T
P
K
V
V
E
K
I
Site 11
Y102
V
V
E
K
I
A
E
Y
K
R
Q
N
P
T
M
Site 12
T128
E
R
V
C
D
N
D
T
V
P
S
V
S
S
I
Site 13
S131
C
D
N
D
T
V
P
S
V
S
S
I
N
R
I
Site 14
T141
S
I
N
R
I
I
R
T
K
V
Q
Q
P
P
N
Site 15
S154
P
N
Q
P
V
P
A
S
S
H
S
I
V
S
T
Site 16
S155
N
Q
P
V
P
A
S
S
H
S
I
V
S
T
G
Site 17
T161
S
S
H
S
I
V
S
T
G
S
V
T
Q
V
S
Site 18
S168
T
G
S
V
T
Q
V
S
S
V
S
T
D
S
A
Site 19
S169
G
S
V
T
Q
V
S
S
V
S
T
D
S
A
G
Site 20
S171
V
T
Q
V
S
S
V
S
T
D
S
A
G
S
S
Site 21
T172
T
Q
V
S
S
V
S
T
D
S
A
G
S
S
Y
Site 22
S174
V
S
S
V
S
T
D
S
A
G
S
S
Y
S
I
Site 23
S177
V
S
T
D
S
A
G
S
S
Y
S
I
S
G
I
Site 24
S178
S
T
D
S
A
G
S
S
Y
S
I
S
G
I
L
Site 25
S189
S
G
I
L
G
I
T
S
P
S
A
D
T
N
K
Site 26
S206
R
D
E
G
I
Q
E
S
P
V
P
N
G
H
S
Site 27
T230
Q
M
R
G
D
L
F
T
Q
Q
Q
L
E
V
L
Site 28
Y246
R
V
F
E
R
Q
H
Y
S
D
I
F
T
T
T
Site 29
S247
V
F
E
R
Q
H
Y
S
D
I
F
T
T
T
E
Site 30
T251
Q
H
Y
S
D
I
F
T
T
T
E
P
I
K
P
Site 31
S265
P
E
Q
T
T
E
Y
S
A
M
A
S
L
A
G
Site 32
S269
T
E
Y
S
A
M
A
S
L
A
G
G
L
D
D
Site 33
S283
D
M
K
A
N
L
A
S
P
T
P
A
D
I
G
Site 34
T285
K
A
N
L
A
S
P
T
P
A
D
I
G
S
S
Site 35
S291
P
T
P
A
D
I
G
S
S
V
P
G
P
Q
S
Site 36
S292
T
P
A
D
I
G
S
S
V
P
G
P
Q
S
Y
Site 37
S298
S
S
V
P
G
P
Q
S
Y
P
I
V
T
G
R
Site 38
Y299
S
V
P
G
P
Q
S
Y
P
I
V
T
G
R
D
Site 39
S309
V
T
G
R
D
L
A
S
T
T
L
P
G
Y
P
Site 40
T310
T
G
R
D
L
A
S
T
T
L
P
G
Y
P
P
Site 41
T311
G
R
D
L
A
S
T
T
L
P
G
Y
P
P
H
Site 42
Y315
A
S
T
T
L
P
G
Y
P
P
H
V
P
P
A
Site 43
S326
V
P
P
A
G
Q
G
S
Y
S
A
P
T
L
T
Site 44
Y327
P
P
A
G
Q
G
S
Y
S
A
P
T
L
T
G
Site 45
S328
P
A
G
Q
G
S
Y
S
A
P
T
L
T
G
M
Site 46
T333
S
Y
S
A
P
T
L
T
G
M
V
P
G
S
E
Site 47
S339
L
T
G
M
V
P
G
S
E
F
S
G
S
P
Y
Site 48
S342
M
V
P
G
S
E
F
S
G
S
P
Y
S
H
P
Site 49
S344
P
G
S
E
F
S
G
S
P
Y
S
H
P
Q
Y
Site 50
Y346
S
E
F
S
G
S
P
Y
S
H
P
Q
Y
S
S
Site 51
S347
E
F
S
G
S
P
Y
S
H
P
Q
Y
S
S
Y
Site 52
Y351
S
P
Y
S
H
P
Q
Y
S
S
Y
N
D
S
W
Site 53
Y354
S
H
P
Q
Y
S
S
Y
N
D
S
W
R
F
P
Site 54
S368
P
N
P
G
L
L
G
S
P
Y
Y
Y
S
A
A
Site 55
Y370
P
G
L
L
G
S
P
Y
Y
Y
S
A
A
A
R
Site 56
Y371
G
L
L
G
S
P
Y
Y
Y
S
A
A
A
R
G
Site 57
S373
L
G
S
P
Y
Y
Y
S
A
A
A
R
G
A
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation