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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MUC2
Full Name:
Mucin-2
Alias:
intestinal mucin-2; MLP; mucin 2, intestinal/tracheal; mucin 2, oligomeric mucus/gel-forming; mucin-2; mucin-like; SMUC
Type:
Extracellular matrix
Mass (Da):
540300
Number AA:
UniProt ID:
Q02817
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0070702
GO:0070703
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
A
A
V
C
L
A
L
S
L
A
G
G
S
E
L
Site 2
S21
A
L
S
L
A
G
G
S
E
L
Q
T
E
G
R
Site 3
T25
A
G
G
S
E
L
Q
T
E
G
R
T
R
Y
H
Site 4
Y31
Q
T
E
G
R
T
R
Y
H
G
R
N
V
C
S
Site 5
Y45
S
T
W
G
N
F
H
Y
K
T
F
D
G
D
V
Site 6
Y61
R
F
P
G
L
C
D
Y
N
F
A
S
D
C
R
Site 7
S70
F
A
S
D
C
R
G
S
Y
K
E
F
A
V
H
Site 8
Y71
A
S
D
C
R
G
S
Y
K
E
F
A
V
H
L
Site 9
S131
P
G
L
L
I
E
K
S
D
A
Y
T
K
V
Y
Site 10
Y134
L
I
E
K
S
D
A
Y
T
K
V
Y
S
R
A
Site 11
T135
I
E
K
S
D
A
Y
T
K
V
Y
S
R
A
G
Site 12
Y138
S
D
A
Y
T
K
V
Y
S
R
A
G
L
T
L
Site 13
S139
D
A
Y
T
K
V
Y
S
R
A
G
L
T
L
M
Site 14
Y172
T
C
G
L
C
G
D
Y
N
G
L
Q
S
Y
S
Site 15
S177
G
D
Y
N
G
L
Q
S
Y
S
E
F
L
S
D
Site 16
S179
Y
N
G
L
Q
S
Y
S
E
F
L
S
D
G
V
Site 17
S183
Q
S
Y
S
E
F
L
S
D
G
V
L
F
S
P
Site 18
S217
E
E
E
V
A
P
A
S
C
S
E
H
R
A
E
Site 19
S219
E
V
A
P
A
S
C
S
E
H
R
A
E
C
E
Site 20
Y246
D
L
V
P
L
E
P
Y
L
R
A
C
Q
Q
D
Site 21
T267
G
D
T
C
V
C
S
T
V
A
E
F
S
R
Q
Site 22
S272
C
S
T
V
A
E
F
S
R
Q
C
S
H
A
G
Site 23
S276
A
E
F
S
R
Q
C
S
H
A
G
G
R
P
G
Site 24
T289
P
G
N
W
R
T
A
T
L
C
P
K
T
C
P
Site 25
S304
G
N
L
V
Y
L
E
S
G
S
P
C
M
D
T
Site 26
T311
S
G
S
P
C
M
D
T
C
S
H
L
E
V
S
Site 27
S313
S
P
C
M
D
T
C
S
H
L
E
V
S
S
L
Site 28
S318
T
C
S
H
L
E
V
S
S
L
C
E
E
H
R
Site 29
S319
C
S
H
L
E
V
S
S
L
C
E
E
H
R
M
Site 30
Y337
F
C
P
E
G
T
V
Y
D
D
I
G
D
S
G
Site 31
S343
V
Y
D
D
I
G
D
S
G
C
V
P
V
S
Q
Site 32
Y360
C
R
L
H
G
H
L
Y
T
P
G
Q
E
I
T
Site 33
T361
R
L
H
G
H
L
Y
T
P
G
Q
E
I
T
N
Site 34
T390
K
D
L
P
C
P
G
T
C
A
L
E
G
G
S
Site 35
T401
E
G
G
S
H
I
T
T
F
D
G
K
T
Y
T
Site 36
T406
I
T
T
F
D
G
K
T
Y
T
F
H
G
D
C
Site 37
Y407
T
T
F
D
G
K
T
Y
T
F
H
G
D
C
Y
Site 38
Y414
Y
T
F
H
G
D
C
Y
Y
V
L
A
K
G
D
Site 39
Y415
T
F
H
G
D
C
Y
Y
V
L
A
K
G
D
H
Site 40
S425
A
K
G
D
H
N
D
S
Y
A
L
L
G
E
L
Site 41
Y426
K
G
D
H
N
D
S
Y
A
L
L
G
E
L
A
Site 42
T446
D
K
Q
T
C
L
K
T
V
V
L
L
A
D
K
Site 43
S481
N
L
P
H
V
T
A
S
F
S
V
F
R
P
S
Site 44
S483
P
H
V
T
A
S
F
S
V
F
R
P
S
S
Y
Site 45
S520
F
V
T
L
D
Q
A
S
Q
G
Q
V
Q
G
L
Site 46
T541
L
E
G
D
D
F
K
T
A
S
G
L
V
E
A
Site 47
S575
D
W
L
D
D
P
C
S
L
N
I
E
S
A
N
Site 48
Y583
L
N
I
E
S
A
N
Y
A
E
H
W
C
S
L
Site 49
T594
W
C
S
L
L
K
K
T
E
T
P
F
G
R
C
Site 50
T596
S
L
L
K
K
T
E
T
P
F
G
R
C
H
S
Site 51
S603
T
P
F
G
R
C
H
S
A
V
D
P
A
E
Y
Site 52
Y610
S
A
V
D
P
A
E
Y
Y
K
R
C
K
Y
D
Site 53
Y611
A
V
D
P
A
E
Y
Y
K
R
C
K
Y
D
T
Site 54
Y669
P
N
S
Q
V
F
L
Y
N
L
T
T
C
Q
Q
Site 55
S680
T
C
Q
Q
T
C
R
S
L
S
E
A
D
S
H
Site 56
S682
Q
Q
T
C
R
S
L
S
E
A
D
S
H
C
L
Site 57
S686
R
S
L
S
E
A
D
S
H
C
L
E
G
F
A
Site 58
T704
G
C
G
C
P
D
H
T
F
L
D
E
K
G
R
Site 59
Y721
P
L
A
K
C
S
C
Y
H
R
G
L
Y
L
E
Site 60
S758
Q
I
R
L
I
G
Q
S
C
T
A
P
K
I
H
Site 61
T776
S
N
L
T
A
L
A
T
S
K
P
R
A
L
S
Site 62
S783
T
S
K
P
R
A
L
S
C
Q
T
L
A
A
G
Site 63
Y829
C
V
H
N
N
D
L
Y
S
S
G
A
K
I
K
Site 64
Y863
C
H
G
T
C
S
I
Y
G
S
G
H
Y
I
T
Site 65
Y868
S
I
Y
G
S
G
H
Y
I
T
F
D
G
K
Y
Site 66
Y875
Y
I
T
F
D
G
K
Y
Y
D
F
D
G
H
C
Site 67
Y876
I
T
F
D
G
K
Y
Y
D
F
D
G
H
C
S
Site 68
Y884
D
F
D
G
H
C
S
Y
V
A
V
Q
D
Y
C
Site 69
Y890
S
Y
V
A
V
Q
D
Y
C
G
Q
N
S
S
L
Site 70
S895
Q
D
Y
C
G
Q
N
S
S
L
G
S
F
S
I
Site 71
S896
D
Y
C
G
Q
N
S
S
L
G
S
F
S
I
I
Site 72
S899
G
Q
N
S
S
L
G
S
F
S
I
I
T
E
N
Site 73
Y949
D
E
G
H
H
V
A
Y
T
T
R
E
V
G
Q
Site 74
T950
E
G
H
H
V
A
Y
T
T
R
E
V
G
Q
Y
Site 75
Y957
T
T
R
E
V
G
Q
Y
L
V
V
E
S
S
T
Site 76
S1013
R
D
H
M
V
V
S
S
E
L
D
F
G
N
S
Site 77
S1020
S
E
L
D
F
G
N
S
W
K
E
A
P
T
C
Site 78
S1031
A
P
T
C
P
D
V
S
T
N
P
E
P
C
S
Site 79
T1032
P
T
C
P
D
V
S
T
N
P
E
P
C
S
L
Site 80
S1038
S
T
N
P
E
P
C
S
L
N
P
H
R
R
S
Site 81
S1045
S
L
N
P
H
R
R
S
W
A
E
K
Q
C
S
Site 82
S1052
S
W
A
E
K
Q
C
S
I
L
K
S
S
V
F
Site 83
S1064
S
V
F
S
I
C
H
S
K
V
D
P
K
P
F
Site 84
Y1072
K
V
D
P
K
P
F
Y
E
A
C
V
H
D
S
Site 85
T1147
R
S
F
E
T
C
R
T
I
N
G
I
H
S
N
Site 86
S1153
R
T
I
N
G
I
H
S
N
I
S
V
S
Y
L
Site 87
S1156
N
G
I
H
S
N
I
S
V
S
Y
L
E
G
C
Site 88
S1158
I
H
S
N
I
S
V
S
Y
L
E
G
C
Y
P
Site 89
Y1164
V
S
Y
L
E
G
C
Y
P
R
C
P
K
D
R
Site 90
Y1174
C
P
K
D
R
P
I
Y
E
E
D
L
K
K
C
Site 91
T1183
E
D
L
K
K
C
V
T
A
D
K
C
G
C
Y
Site 92
Y1190
T
A
D
K
C
G
C
Y
V
E
D
T
H
Y
P
Site 93
Y1196
C
Y
V
E
D
T
H
Y
P
P
G
A
S
V
P
Site 94
S1210
P
T
E
E
T
C
K
S
C
V
C
T
N
S
S
Site 95
S1217
S
C
V
C
T
N
S
S
Q
V
V
C
R
P
E
Site 96
T1232
E
G
K
I
L
N
Q
T
Q
D
G
A
F
C
Y
Site 97
S1257
E
K
H
F
N
I
C
S
I
T
T
R
P
S
T
Site 98
T1259
H
F
N
I
C
S
I
T
T
R
P
S
T
L
T
Site 99
S1263
C
S
I
T
T
R
P
S
T
L
T
T
F
T
T
Site 100
T1276
T
T
I
T
L
P
T
T
P
T
S
F
T
T
T
Site 101
S1279
T
L
P
T
T
P
T
S
F
T
T
T
T
T
T
Site 102
T1283
T
P
T
S
F
T
T
T
T
T
T
T
T
P
T
Site 103
T1286
S
F
T
T
T
T
T
T
T
T
P
T
S
S
T
Site 104
T1287
F
T
T
T
T
T
T
T
T
P
T
S
S
T
V
Site 105
T1288
T
T
T
T
T
T
T
T
P
T
S
S
T
V
L
Site 106
S1291
T
T
T
T
T
P
T
S
S
T
V
L
S
T
T
Site 107
S1292
T
T
T
T
P
T
S
S
T
V
L
S
T
T
P
Site 108
T1293
T
T
T
P
T
S
S
T
V
L
S
T
T
P
K
Site 109
S1315
W
I
N
E
D
H
P
S
S
G
S
D
D
G
D
Site 110
S1316
I
N
E
D
H
P
S
S
G
S
D
D
G
D
R
Site 111
S1340
P
E
D
I
E
C
R
S
V
K
D
P
H
L
S
Site 112
S1347
S
V
K
D
P
H
L
S
L
E
Q
H
G
Q
K
Site 113
Y1380
N
G
P
F
G
L
C
Y
D
Y
K
I
R
V
N
Site 114
T1398
P
M
D
K
C
I
T
T
P
S
P
P
T
T
T
Site 115
S1400
D
K
C
I
T
T
P
S
P
P
T
T
T
P
S
Site 116
T1403
I
T
T
P
S
P
P
T
T
T
P
S
P
P
P
Site 117
T1404
T
T
P
S
P
P
T
T
T
P
S
P
P
P
T
Site 118
T1405
T
P
S
P
P
T
T
T
P
S
P
P
P
T
T
Site 119
S1407
S
P
P
T
T
T
P
S
P
P
P
T
T
T
T
Site 120
T1411
T
T
P
S
P
P
P
T
T
T
T
T
L
P
P
Site 121
T1412
T
P
S
P
P
P
T
T
T
T
T
L
P
P
T
Site 122
T1414
S
P
P
P
T
T
T
T
T
L
P
P
T
T
T
Site 123
T1415
P
P
P
T
T
T
T
T
L
P
P
T
T
T
P
Site 124
T1419
T
T
T
T
L
P
P
T
T
T
P
S
P
P
T
Site 125
T1420
T
T
T
L
P
P
T
T
T
P
S
P
P
T
T
Site 126
T1421
T
T
L
P
P
T
T
T
P
S
P
P
T
T
T
Site 127
S1423
L
P
P
T
T
T
P
S
P
P
T
T
T
T
T
Site 128
T1427
T
T
P
S
P
P
T
T
T
T
T
T
P
P
P
Site 129
T1429
P
S
P
P
T
T
T
T
T
T
P
P
P
T
T
Site 130
T1430
S
P
P
T
T
T
T
T
T
P
P
P
T
T
T
Site 131
T1431
P
P
T
T
T
T
T
T
P
P
P
T
T
T
P
Site 132
T1435
T
T
T
T
P
P
P
T
T
T
P
S
P
P
I
Site 133
T1436
T
T
T
P
P
P
T
T
T
P
S
P
P
I
T
Site 134
T1437
T
T
P
P
P
T
T
T
P
S
P
P
I
T
T
Site 135
S1439
P
P
P
T
T
T
P
S
P
P
I
T
T
T
T
Site 136
T1443
T
T
P
S
P
P
I
T
T
T
T
T
P
L
P
Site 137
T1445
P
S
P
P
I
T
T
T
T
T
P
L
P
T
T
Site 138
T1447
P
P
I
T
T
T
T
T
P
L
P
T
T
T
P
Site 139
T1451
T
T
T
T
P
L
P
T
T
T
P
S
P
P
I
Site 140
T1452
T
T
T
P
L
P
T
T
T
P
S
P
P
I
S
Site 141
T1453
T
T
P
L
P
T
T
T
P
S
P
P
I
S
T
Site 142
S1455
P
L
P
T
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T1469
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S1471
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T1474
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T1475
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T1476
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S1478
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Site 155
S1485
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Site 156
T1497
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Site 157
T1498
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Site 158
T1499
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Site 159
S1501
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Site 160
T1505
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Site 161
T1506
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T1509
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Site 163
S1513
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Site 164
T1516
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Site 165
T1520
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Site 166
S1540
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Site 167
T1543
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Site 168
T1544
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Site 169
T1545
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Site 170
T1548
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Site 171
S1552
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Site 172
T1555
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Site 173
T1559
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Site 174
T1560
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Site 175
T1561
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Site 176
S1563
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Site 177
T1567
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Site 178
T1568
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Site 179
T1569
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Site 180
T1570
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Site 181
T1571
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Site 182
S1579
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Site 183
T1583
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Site 184
T1585
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Site 185
S1587
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Site 186
T1593
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Site 187
T1594
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Site 188
T1595
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Site 189
S1603
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Site 190
T1662
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Site 191
T1664
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Site 192
S1666
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Site 193
T1670
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Site 194
T1672
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Site 195
T1673
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Site 196
T1674
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Site 197
T1678
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Site 198
T1679
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Site 199
T1680
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Site 200
S1682
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Site 201
S1683
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Site 202
T1686
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Site 203
T1687
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Site 204
T1688
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Site 205
S1690
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Site 206
T1694
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Site 207
T1697
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Site 208
T1698
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Site 209
S1700
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Site 210
T1702
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Site 211
T1703
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Site 212
T1704
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Site 213
S1706
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Site 214
S1707
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Site 215
T1710
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Site 216
T1711
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Site 217
T1712
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Site 218
T1713
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Site 219
T1714
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Site 220
S1716
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Site 221
S1717
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Site 222
T1718
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Site 223
T1720
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Site 224
S1722
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Site 225
T1726
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Site 226
T1727
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T1729
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T1730
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Site 229
S1732
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Site 230
T1734
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Site 231
T1736
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Site 232
S1738
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Site 233
T1742
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Site 234
T1745
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Site 235
T1746
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Site 236
T1750
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Site 237
T1752
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Site 238
S1754
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Site 239
T1757
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Site 240
T1758
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Site 241
T1759
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Site 242
S1764
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Site 243
T1766
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F
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F
Site 244
T1769
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F
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Site 245
S1771
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F
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Site 246
S1774
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P
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F
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F
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Site 247
T1775
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T
F
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F
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T
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T
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C
Site 248
T1777
F
S
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F
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T
T
T
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T
T
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C
V
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Site 249
T1890
T
T
M
T
T
T
T
T
E
N
P
T
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P
T
Site 250
T1894
T
T
T
T
E
N
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T
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P
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I
Site 251
T1897
T
E
N
P
T
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P
T
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I
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T
T
Site 252
T1898
E
N
P
T
P
P
T
T
T
P
I
T
T
T
T
Site 253
T1899
N
P
T
P
P
T
T
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I
T
T
T
T
T
Site 254
T1906
T
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Site 255
T1908
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T
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V
T
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T
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T
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T
G
Site 256
T1910
T
T
T
T
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T
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T
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T
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T
Q
Site 257
T1912
T
T
V
T
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T
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T
G
T
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T
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Site 258
T1916
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T
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G
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T
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T
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T
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Site 259
T1918
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T
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T
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T
T
T
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I
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Site 260
T1920
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T
G
T
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T
P
T
T
T
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I
T
T
T
Site 261
T1921
T
G
T
Q
T
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T
T
T
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I
T
T
T
T
Site 262
T1922
G
T
Q
T
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T
T
T
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I
T
T
T
T
T
Site 263
T4189
T
T
V
T
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T
P
T
P
T
G
T
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T
G
Site 264
T4193
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T
P
T
P
T
G
T
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T
G
P
P
T
H
Site 265
T4195
P
T
P
T
G
T
Q
T
G
P
P
T
H
T
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Site 266
T4199
G
T
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T
G
P
P
T
H
T
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T
A
P
I
Site 267
T4210
T
A
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I
A
E
L
T
T
S
N
P
P
P
E
Site 268
S4212
P
I
A
E
L
T
T
S
N
P
P
P
E
S
S
Site 269
S4218
T
S
N
P
P
P
E
S
S
T
P
Q
T
S
R
Site 270
S4219
S
N
P
P
P
E
S
S
T
P
Q
T
S
R
S
Site 271
T4220
N
P
P
P
E
S
S
T
P
Q
T
S
R
S
T
Site 272
T4223
P
E
S
S
T
P
Q
T
S
R
S
T
S
S
P
Site 273
S4224
E
S
S
T
P
Q
T
S
R
S
T
S
S
P
L
Site 274
S4226
S
T
P
Q
T
S
R
S
T
S
S
P
L
T
E
Site 275
T4227
T
P
Q
T
S
R
S
T
S
S
P
L
T
E
S
Site 276
S4228
P
Q
T
S
R
S
T
S
S
P
L
T
E
S
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Site 277
S4229
Q
T
S
R
S
T
S
S
P
L
T
E
S
T
T
Site 278
T4232
R
S
T
S
S
P
L
T
E
S
T
T
L
L
S
Site 279
S4234
T
S
S
P
L
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E
S
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T
L
L
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T
L
Site 280
T4235
S
S
P
L
T
E
S
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T
L
L
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L
P
Site 281
T4236
S
P
L
T
E
S
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L
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T
L
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P
Site 282
T4250
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A
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E
M
T
S
T
A
P
P
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P
T
Site 283
S4254
M
T
S
T
A
P
P
S
T
P
T
A
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T
T
Site 284
T4255
T
S
T
A
P
P
S
T
P
T
A
P
T
T
T
Site 285
T4261
S
T
P
T
A
P
T
T
T
S
G
G
H
T
L
Site 286
S4263
P
T
A
P
T
T
T
S
G
G
H
T
L
S
P
Site 287
T4267
T
T
T
S
G
G
H
T
L
S
P
P
P
S
T
Site 288
S4269
T
S
G
G
H
T
L
S
P
P
P
S
T
T
T
Site 289
S4273
H
T
L
S
P
P
P
S
T
T
T
S
P
P
G
Site 290
T4274
T
L
S
P
P
P
S
T
T
T
S
P
P
G
T
Site 291
T4275
L
S
P
P
P
S
T
T
T
S
P
P
G
T
P
Site 292
T4276
S
P
P
P
S
T
T
T
S
P
P
G
T
P
T
Site 293
S4277
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P
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T
T
T
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P
G
T
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T
R
Site 294
T4281
T
T
T
S
P
P
G
T
P
T
R
G
T
T
T
Site 295
T4286
P
G
T
P
T
R
G
T
T
T
G
S
S
S
A
Site 296
T4287
G
T
P
T
R
G
T
T
T
G
S
S
S
A
P
Site 297
T4288
T
P
T
R
G
T
T
T
G
S
S
S
A
P
T
Site 298
S4290
T
R
G
T
T
T
G
S
S
S
A
P
T
P
S
Site 299
S4291
R
G
T
T
T
G
S
S
S
A
P
T
P
S
T
Site 300
S4292
G
T
T
T
G
S
S
S
A
P
T
P
S
T
V
Site 301
T4295
T
G
S
S
S
A
P
T
P
S
T
V
Q
T
T
Site 302
S4297
S
S
S
A
P
T
P
S
T
V
Q
T
T
T
T
Site 303
T4298
S
S
A
P
T
P
S
T
V
Q
T
T
T
T
S
Site 304
T4301
P
T
P
S
T
V
Q
T
T
T
T
S
A
W
T
Site 305
T4308
T
T
T
T
S
A
W
T
P
T
P
T
P
L
S
Site 306
T4310
T
T
S
A
W
T
P
T
P
T
P
L
S
T
P
Site 307
T4312
S
A
W
T
P
T
P
T
P
L
S
T
P
S
I
Site 308
S4315
T
P
T
P
T
P
L
S
T
P
S
I
I
R
T
Site 309
T4316
P
T
P
T
P
L
S
T
P
S
I
I
R
T
T
Site 310
T4322
S
T
P
S
I
I
R
T
T
G
L
R
P
Y
P
Site 311
T4323
T
P
S
I
I
R
T
T
G
L
R
P
Y
P
S
Site 312
Y4328
R
T
T
G
L
R
P
Y
P
S
S
V
L
I
C
Site 313
Y4342
C
C
V
L
N
D
T
Y
Y
A
P
G
E
E
V
Site 314
Y4343
C
V
L
N
D
T
Y
Y
A
P
G
E
E
V
Y
Site 315
Y4372
L
S
C
T
L
E
F
Y
N
W
S
C
P
S
T
Site 316
S4375
T
L
E
F
Y
N
W
S
C
P
S
T
P
S
P
Site 317
S4378
F
Y
N
W
S
C
P
S
T
P
S
P
T
P
T
Site 318
T4379
Y
N
W
S
C
P
S
T
P
S
P
T
P
T
P
Site 319
S4381
W
S
C
P
S
T
P
S
P
T
P
T
P
S
K
Site 320
T4383
C
P
S
T
P
S
P
T
P
T
P
S
K
S
T
Site 321
T4385
S
T
P
S
P
T
P
T
P
S
K
S
T
P
T
Site 322
S4387
P
S
P
T
P
T
P
S
K
S
T
P
T
P
S
Site 323
S4389
P
T
P
T
P
S
K
S
T
P
T
P
S
K
P
Site 324
T4390
T
P
T
P
S
K
S
T
P
T
P
S
K
P
S
Site 325
T4392
T
P
S
K
S
T
P
T
P
S
K
P
S
S
T
Site 326
S4394
S
K
S
T
P
T
P
S
K
P
S
S
T
P
S
Site 327
S4397
T
P
T
P
S
K
P
S
S
T
P
S
K
P
T
Site 328
S4398
P
T
P
S
K
P
S
S
T
P
S
K
P
T
P
Site 329
T4399
T
P
S
K
P
S
S
T
P
S
K
P
T
P
G
Site 330
S4401
S
K
P
S
S
T
P
S
K
P
T
P
G
T
K
Site 331
T4404
S
S
T
P
S
K
P
T
P
G
T
K
P
P
E
Site 332
T4407
P
S
K
P
T
P
G
T
K
P
P
E
C
P
D
Site 333
Y4437
C
F
M
A
T
C
K
Y
N
N
T
V
E
I
V
Site 334
T4440
A
T
C
K
Y
N
N
T
V
E
I
V
K
V
E
Site 335
S4457
P
P
P
M
P
T
C
S
N
G
L
Q
P
V
R
Site 336
Y4489
T
G
W
G
D
P
H
Y
V
T
F
D
G
L
Y
Site 337
Y4496
Y
V
T
F
D
G
L
Y
Y
S
Y
Q
G
N
C
Site 338
Y4497
V
T
F
D
G
L
Y
Y
S
Y
Q
G
N
C
T
Site 339
Y4505
S
Y
Q
G
N
C
T
Y
V
L
V
E
E
I
S
Site 340
Y4521
S
V
D
N
F
G
V
Y
I
D
N
Y
H
C
D
Site 341
Y4525
F
G
V
Y
I
D
N
Y
H
C
D
P
N
D
K
Site 342
S4534
C
D
P
N
D
K
V
S
C
P
R
T
L
I
V
Site 343
T4538
D
K
V
S
C
P
R
T
L
I
V
R
H
E
T
Site 344
Y4581
K
K
Y
G
L
E
V
Y
Q
S
G
I
N
Y
V
Site 345
S4606
S
Y
N
G
L
S
F
S
V
R
L
P
Y
H
R
Site 346
Y4611
S
F
S
V
R
L
P
Y
H
R
F
G
N
N
T
Site 347
T4626
K
G
Q
C
G
T
C
T
N
T
T
S
D
D
C
Site 348
S4630
G
T
C
T
N
T
T
S
D
D
C
I
L
P
S
Site 349
S4664
S
K
P
H
C
P
H
S
S
S
T
T
K
R
P
Site 350
S4666
P
H
C
P
H
S
S
S
T
T
K
R
P
A
V
Site 351
T4668
C
P
H
S
S
S
T
T
K
R
P
A
V
T
V
Site 352
T4674
T
T
K
R
P
A
V
T
V
P
G
G
G
K
T
Site 353
T4682
V
P
G
G
G
K
T
T
P
H
K
D
C
T
P
Site 354
T4688
T
T
P
H
K
D
C
T
P
S
P
L
C
Q
L
Site 355
S4690
P
H
K
D
C
T
P
S
P
L
C
Q
L
I
K
Site 356
Y4714
L
V
P
P
Q
H
Y
Y
D
A
C
V
F
D
S
Site 357
Y4768
E
C
P
S
H
R
E
Y
Q
A
C
G
P
A
E
Site 358
T4778
C
G
P
A
E
E
P
T
C
K
S
S
S
S
Q
Site 359
S4781
A
E
E
P
T
C
K
S
S
S
S
Q
Q
N
N
Site 360
S4784
P
T
C
K
S
S
S
S
Q
Q
N
N
T
V
L
Site 361
T4789
S
S
S
Q
Q
N
N
T
V
L
V
E
G
C
F
Site 362
T4860
R
C
S
Q
K
P
V
T
H
C
V
E
D
G
T
Site 363
Y4868
H
C
V
E
D
G
T
Y
L
A
T
E
V
N
P
Site 364
S4890
T
V
C
K
C
N
T
S
L
C
K
E
K
P
S
Site 365
S4897
S
L
C
K
E
K
P
S
V
C
P
L
G
F
E
Site 366
S4907
P
L
G
F
E
V
K
S
K
M
V
P
G
R
C
Site 367
Y4933
C
V
H
G
N
A
E
Y
Q
P
G
S
P
V
Y
Site 368
S4937
N
A
E
Y
Q
P
G
S
P
V
Y
S
S
K
C
Site 369
Y4940
Y
Q
P
G
S
P
V
Y
S
S
K
C
Q
D
C
Site 370
S4941
Q
P
G
S
P
V
Y
S
S
K
C
Q
D
C
V
Site 371
S4974
V
P
C
N
T
S
C
S
P
G
F
E
L
M
E
Site 372
S5014
L
K
P
G
D
F
K
S
D
P
K
N
N
C
T
Site 373
T5066
N
G
C
C
K
T
C
T
P
R
N
E
T
R
V
Site 374
T5071
T
C
T
P
R
N
E
T
R
V
P
C
S
T
V
Site 375
S5076
N
E
T
R
V
P
C
S
T
V
P
V
T
T
E
Site 376
T5077
E
T
R
V
P
C
S
T
V
P
V
T
T
E
V
Site 377
S5120
Q
A
L
D
H
S
C
S
C
C
K
E
E
K
T
Site 378
T5127
S
C
C
K
E
E
K
T
S
Q
R
E
V
V
L
Site 379
S5128
C
C
K
E
E
K
T
S
Q
R
E
V
V
L
S
Site 380
S5135
S
Q
R
E
V
V
L
S
C
P
N
G
G
S
L
Site 381
S5141
L
S
C
P
N
G
G
S
L
T
H
T
Y
T
H
Site 382
T5145
N
G
G
S
L
T
H
T
Y
T
H
I
E
S
C
Site 383
Y5146
G
G
S
L
T
H
T
Y
T
H
I
E
S
C
Q
Site 384
T5147
G
S
L
T
H
T
Y
T
H
I
E
S
C
Q
C
Site 385
T5157
E
S
C
Q
C
Q
D
T
V
C
G
L
P
T
G
Site 386
T5165
V
C
G
L
P
T
G
T
S
R
R
A
R
R
S
Site 387
S5166
C
G
L
P
T
G
T
S
R
R
A
R
R
S
P
Site 388
S5172
T
S
R
R
A
R
R
S
P
R
H
L
G
S
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation