PhosphoNET

           
Protein Info 
   
Short Name:  CYP4A11
Full Name:  Cytochrome P450 4A11
Alias:  20-hydroxyeicosatetraenoic acid synthase; CP4AB; CP4Y; CYP4A2; CYP4AII; CYPIVA11; Cytochrome P450 4A11; Cytochrome P450, 4, A, 11; Cytochrome P450, family 4, subfamily A, polypeptide 11; Cytochrome P-450HK-omega; Cytochrome P450HL-omega; Fatty acid omega-hydroxylase; Lauric acid omega-hydroxylase; P-450 HK omega; P450-HL-omega
Type:  Cofactor and Vitamin Metabolism - retinol; EC 1.14.15.3; Endoplasmic reticulum; Lipid Metabolism - fatty acid; Oxidoreductase; Lipid Metabolism - arachidonic acid
Mass (Da):  59329
Number AA:  519
UniProt ID:  Q02928
International Prot ID:  IPI00465089
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005789  GO:0019898  GO:0005792 Uniprot OncoNet
Molecular Function:  GO:0018685  GO:0009055  GO:0008393 PhosphoSite+ KinaseNET
Biological Process:  GO:0001676  GO:0055114   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S7_MSVSVLSPSRLLGD
Site 2Y100GKVRVQLYDPDYMKV
Site 3Y104VQLYDPDYMKVILGR
Site 4S112MKVILGRSDPKSHGS
Site 5S116LGRSDPKSHGSYRFL
Site 6S119SDPKSHGSYRFLAPW
Site 7Y120DPKSHGSYRFLAPWI
Site 8T147FQHRRMLTPAFHYDI
Site 9Y158HYDILKPYVGLMADS
Site 10S181EELLGQDSPLEVFQH
Site 11S207CAFSHQGSIQVDRNS
Site 12S214SIQVDRNSQSYIQAI
Site 13Y217VDRNSQSYIQAISDL
Site 14T241NAFHQNDTIYSLTSA
Site 15Y243FHQNDTIYSLTSAGR
Site 16S244HQNDTIYSLTSAGRW
Site 17S247DTIYSLTSAGRWTHR
Site 18T252LTSAGRWTHRACQLA
Site 19T317DLRAEVDTFMFEGHD
Site 20S328EGHDTTASGISWILY
Site 21S353RCREEIHSLLGDGAS
Site 22S360SLLGDGASITWNHLD
Site 23S394PGIGRELSTPVTFPD
Site 24T395GIGRELSTPVTFPDG
Site 25T398RELSTPVTFPDGRSL
Site 26S440PFRFAPGSAQHSHAF
Site 27S444APGSAQHSHAFLPFS
Site 28S451SHAFLPFSGGSRNCI
Site 29T485FELLPDPTRIPIPIA
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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