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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HHEX
Full Name:
Hematopoietically-expressed homeobox protein HHEX
Alias:
hematopoietically expressed homeobox; HEX; HMPH; HOX11L-PEN; PRH; PRHX
Type:
Transcription factor
Mass (Da):
30022
Number AA:
270
UniProt ID:
Q03014
International Prot ID:
IPI00008771
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0008190
GO:0043565
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0016055
GO:0009952
GO:0007049
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y33
P
A
H
P
T
P
F
Y
I
E
D
I
L
G
R
Site 2
T46
G
R
G
P
A
A
P
T
P
A
P
T
L
P
S
Site 3
T50
A
A
P
T
P
A
P
T
L
P
S
P
N
S
S
Site 4
S53
T
P
A
P
T
L
P
S
P
N
S
S
F
T
S
Site 5
S56
P
T
L
P
S
P
N
S
S
F
T
S
L
V
S
Site 6
S57
T
L
P
S
P
N
S
S
F
T
S
L
V
S
P
Site 7
T59
P
S
P
N
S
S
F
T
S
L
V
S
P
Y
R
Site 8
S60
S
P
N
S
S
F
T
S
L
V
S
P
Y
R
T
Site 9
S63
S
S
F
T
S
L
V
S
P
Y
R
T
P
V
Y
Site 10
Y65
F
T
S
L
V
S
P
Y
R
T
P
V
Y
E
P
Site 11
T67
S
L
V
S
P
Y
R
T
P
V
Y
E
P
T
P
Site 12
Y70
S
P
Y
R
T
P
V
Y
E
P
T
P
I
H
P
Site 13
T73
R
T
P
V
Y
E
P
T
P
I
H
P
A
F
S
Site 14
Y101
G
G
F
G
G
P
L
Y
P
F
P
R
T
V
N
Site 15
T106
P
L
Y
P
F
P
R
T
V
N
D
Y
T
H
A
Site 16
Y110
F
P
R
T
V
N
D
Y
T
H
A
L
L
R
H
Site 17
T111
P
R
T
V
N
D
Y
T
H
A
L
L
R
H
D
Site 18
S145
K
G
G
Q
V
R
F
S
N
D
Q
T
I
E
L
Site 19
T149
V
R
F
S
N
D
Q
T
I
E
L
E
K
K
F
Site 20
Y161
K
K
F
E
T
Q
K
Y
L
S
P
P
E
R
K
Site 21
S163
F
E
T
Q
K
Y
L
S
P
P
E
R
K
R
L
Site 22
S177
L
A
K
M
L
Q
L
S
E
R
Q
V
K
T
W
Site 23
S202
L
K
Q
E
N
P
Q
S
N
K
K
E
E
L
E
Site 24
S210
N
K
K
E
E
L
E
S
L
D
S
S
C
D
Q
Site 25
S213
E
E
L
E
S
L
D
S
S
C
D
Q
R
Q
D
Site 26
S214
E
L
E
S
L
D
S
S
C
D
Q
R
Q
D
L
Site 27
S223
D
Q
R
Q
D
L
P
S
E
Q
N
K
G
A
S
Site 28
S230
S
E
Q
N
K
G
A
S
L
D
S
S
Q
C
S
Site 29
S233
N
K
G
A
S
L
D
S
S
Q
C
S
P
S
P
Site 30
S234
K
G
A
S
L
D
S
S
Q
C
S
P
S
P
A
Site 31
S237
S
L
D
S
S
Q
C
S
P
S
P
A
S
Q
E
Site 32
S239
D
S
S
Q
C
S
P
S
P
A
S
Q
E
D
L
Site 33
S242
Q
C
S
P
S
P
A
S
Q
E
D
L
E
S
E
Site 34
S248
A
S
Q
E
D
L
E
S
E
I
S
E
D
S
D
Site 35
S251
E
D
L
E
S
E
I
S
E
D
S
D
Q
E
V
Site 36
S254
E
S
E
I
S
E
D
S
D
Q
E
V
D
I
E
Site 37
Y266
D
I
E
G
D
K
S
Y
F
N
A
G
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation