PhosphoNET

           
Protein Info 
   
Short Name:  MLLT1
Full Name:  Protein ENL
Alias:  ENL; LTG19; Myeloid/lymphoid or mixed-lineage leukemia (trithorax); Myeloid/lymphoid or mixed-lineage leukemia (trithorax) translocated to, 1; Myeloid/lymphoid or mixed-lineage leukemia (trithorax) translocated to, 1 (ENL); YEATS domain-containing protein 1; YEATS1
Type:  Transcription regulation
Mass (Da):  62056
Number AA:  559
UniProt ID:  Q03111
International Prot ID:  IPI00100630
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634  GO:0043226  GO:0043227 Uniprot OncoNet
Molecular Function:  GO:0003677  GO:0003702  GO:0003702 PhosphoSite+ KinaseNET
Biological Process:  GO:0006355  GO:0006366  GO:0006351 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T24AQLRKKPTTEGFTHD
Site 2T25QLRKKPTTEGFTHDW
Site 3S58VVFWLHDSFPKPRRV
Site 4Y71RVCKEPPYKVEESGY
Site 5T123HLRCEKLTFNNPTTE
Site 6T129LTFNNPTTEFRYKLL
Site 7T150VMPEGADTVSRPSPD
Site 8S152PEGADTVSRPSPDYP
Site 9S155ADTVSRPSPDYPMLP
Site 10Y158VSRPSPDYPMLPTIP
Site 11T163PDYPMLPTIPLSAFS
Site 12S167MLPTIPLSAFSDPKK
Site 13S170TIPLSAFSDPKKTKP
Site 14T175AFSDPKKTKPSHGSK
Site 15S188SKDANKESSKTSKPH
Site 16S189KDANKESSKTSKPHK
Site 17T191ANKESSKTSKPHKVT
Site 18S192NKESSKTSKPHKVTK
Site 19S209RERPRKDSESKSSSK
Site 20S211RPRKDSESKSSSKEL
Site 21S213RKDSESKSSSKELER
Site 22S215DSESKSSSKELEREQ
Site 23S225LEREQAKSSKDTSRK
Site 24S226EREQAKSSKDTSRKL
Site 25T229QAKSSKDTSRKLGEG
Site 26S230AKSSKDTSRKLGEGR
Site 27S265LKETKLESTSPKGGP
Site 28S267ETKLESTSPKGGPPP
Site 29S283PPPPPRASSKRPATA
Site 30S284PPPPRASSKRPATAD
Site 31T289ASSKRPATADSPKPS
Site 32S292KRPATADSPKPSAKK
Site 33S296TADSPKPSAKKQKKS
Site 34S303SAKKQKKSSSKGSRS
Site 35S304AKKQKKSSSKGSRSA
Site 36S305KKQKKSSSKGSRSAP
Site 37S308KKSSSKGSRSAPGTS
Site 38S310SSSKGSRSAPGTSPR
Site 39T314GSRSAPGTSPRTSSS
Site 40S315SRSAPGTSPRTSSSS
Site 41T318APGTSPRTSSSSSFS
Site 42S319PGTSPRTSSSSSFSD
Site 43S320GTSPRTSSSSSFSDK
Site 44S321TSPRTSSSSSFSDKK
Site 45S322SPRTSSSSSFSDKKP
Site 46S323PRTSSSSSFSDKKPA
Site 47S325TSSSSSFSDKKPAKD
Site 48S334KKPAKDKSSTRGEKV
Site 49S335KPAKDKSSTRGEKVK
Site 50S345GEKVKAESEPREAKK
Site 51S359KALEVEESNSEDEAS
Site 52S361LEVEESNSEDEASFK
Site 53S366SNSEDEASFKSESAQ
Site 54S369EDEASFKSESAQSSP
Site 55S371EASFKSESAQSSPSN
Site 56S374FKSESAQSSPSNSSS
Site 57S375KSESAQSSPSNSSSS
Site 58S377ESAQSSPSNSSSSSD
Site 59S379AQSSPSNSSSSSDSS
Site 60S380QSSPSNSSSSSDSSS
Site 61S381SSPSNSSSSSDSSSD
Site 62S382SPSNSSSSSDSSSDS
Site 63S383PSNSSSSSDSSSDSD
Site 64S385NSSSSSDSSSDSDFE
Site 65S386SSSSSDSSSDSDFEP
Site 66S387SSSSDSSSDSDFEPS
Site 67S389SSDSSSDSDFEPSQN
Site 68S394SDSDFEPSQNHSQGP
Site 69S398FEPSQNHSQGPLRSM
Site 70S404HSQGPLRSMVEDLQS
Site 71S411SMVEDLQSEESDEDD
Site 72S414EDLQSEESDEDDSSS
Site 73S419EESDEDDSSSGEEAA
Site 74S420ESDEDDSSSGEEAAG
Site 75S421SDEDDSSSGEEAAGK
Site 76S435KTNPGRDSRLSFSDS
Site 77S438PGRDSRLSFSDSESD
Site 78S440RDSRLSFSDSESDNS
Site 79S442SRLSFSDSESDNSAD
Site 80S444LSFSDSESDNSADSS
Site 81S447SDSESDNSADSSLPS
Site 82S450ESDNSADSSLPSREP
Site 83S451SDNSADSSLPSREPP
Site 84S454SADSSLPSREPPPPQ
Site 85S468QKPPPPNSKVSGRRS
Site 86S471PPPNSKVSGRRSPES
Site 87S475SKVSGRRSPESCSKP
Site 88S478SGRRSPESCSKPEKI
Site 89S480RRSPESCSKPEKILK
Site 90T490EKILKKGTYDKAYTD
Site 91Y491KILKKGTYDKAYTDE
Site 92Y495KGTYDKAYTDELVEL
Site 93S541TFDFDLFSLDETTVR
Site 94T545DLFSLDETTVRKLQS
Site 95T546LFSLDETTVRKLQSC
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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