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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GNA12
Full Name:
Guanine nucleotide-binding protein subunit alpha-12
Alias:
G alpha 12; Gep; Guanine nucleotide binding protein (G protein) alpha 12; Guanine nucleotide-binding protein alpha-12 subunit
Type:
G protein; G protein, heterotrimeric
Mass (Da):
44279
Number AA:
381
UniProt ID:
Q03113
International Prot ID:
IPI00328744
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0031225
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0003924
GO:0004871
PhosphoSite+
KinaseNET
Biological Process:
GO:0007186
GO:0007596
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S27
A
R
E
R
R
A
G
S
G
A
R
D
A
E
R
Site 2
S40
E
R
E
A
R
R
R
S
R
D
I
D
A
L
L
Site 3
S68
L
L
L
G
A
G
E
S
G
K
S
T
F
L
K
Site 4
S71
G
A
G
E
S
G
K
S
T
F
L
K
Q
M
R
Site 5
T72
A
G
E
S
G
K
S
T
F
L
K
Q
M
R
I
Site 6
Y121
K
L
G
I
P
W
Q
Y
S
E
N
E
K
H
G
Site 7
S155
Q
L
Y
V
P
A
L
S
A
L
W
R
D
S
G
Site 8
S161
L
S
A
L
W
R
D
S
G
I
R
E
A
F
S
Site 9
S168
S
G
I
R
E
A
F
S
R
R
S
E
F
Q
L
Site 10
S171
R
E
A
F
S
R
R
S
E
F
Q
L
G
E
S
Site 11
S178
S
E
F
Q
L
G
E
S
V
K
Y
F
L
D
N
Site 12
Y181
Q
L
G
E
S
V
K
Y
F
L
D
N
L
D
R
Site 13
Y194
D
R
I
G
Q
L
N
Y
F
P
S
K
Q
D
I
Site 14
S197
G
Q
L
N
Y
F
P
S
K
Q
D
I
L
L
A
Site 15
T208
I
L
L
A
R
K
A
T
K
G
I
V
E
H
D
Site 16
S233
V
D
V
G
G
Q
R
S
Q
R
Q
K
W
F
Q
Site 17
Y257
F
M
V
S
S
S
E
Y
D
Q
V
L
M
E
D
Site 18
T267
V
L
M
E
D
R
R
T
N
R
L
V
E
S
M
Site 19
S273
R
T
N
R
L
V
E
S
M
N
I
F
E
T
I
Site 20
Y330
R
L
E
D
V
Q
R
Y
L
V
Q
C
F
D
R
Site 21
S343
D
R
K
R
R
N
R
S
K
P
L
F
H
H
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation