KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ACY1
Full Name:
Aminoacylase-1
Alias:
ACY1D; Acylase; Aminoacylase 1; EC=3.5.1.14; N-acyl-L-amino-acid amidohydrolase
Type:
Enzyme, aminoacylase
Mass (Da):
45885
Number AA:
408
UniProt ID:
Q03154
International Prot ID:
IPI00009268
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0004046
GO:0008237
GO:0046983
PhosphoSite+
KinaseNET
Biological Process:
GO:0006520
GO:0006508
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
G
P
E
E
E
H
P
S
V
T
L
F
R
Q
Y
Site 2
Y19
S
V
T
L
F
R
Q
Y
L
R
I
R
T
V
Q
Site 3
T24
R
Q
Y
L
R
I
R
T
V
Q
P
K
P
D
Y
Site 4
T71
T
W
P
G
T
N
P
T
L
S
S
I
L
L
N
Site 5
S73
P
G
T
N
P
T
L
S
S
I
L
L
N
S
H
Site 6
S74
G
T
N
P
T
L
S
S
I
L
L
N
S
H
T
Site 7
S102
P
F
E
A
F
K
D
S
E
G
Y
I
Y
A
R
Site 8
Y107
K
D
S
E
G
Y
I
Y
A
R
G
A
Q
D
M
Site 9
T138
E
G
H
R
F
P
R
T
I
H
M
T
F
V
P
Site 10
T142
F
P
R
T
I
H
M
T
F
V
P
D
E
E
V
Site 11
T185
A
N
P
T
D
A
F
T
V
F
Y
S
E
R
S
Site 12
Y188
T
D
A
F
T
V
F
Y
S
E
R
S
P
W
W
Site 13
T199
S
P
W
W
V
R
V
T
S
T
G
R
P
G
H
Site 14
S200
P
W
W
V
R
V
T
S
T
G
R
P
G
H
A
Site 15
T201
W
W
V
R
V
T
S
T
G
R
P
G
H
A
S
Site 16
S208
T
G
R
P
G
H
A
S
R
F
M
E
D
T
A
Site 17
T214
A
S
R
F
M
E
D
T
A
A
E
K
L
H
K
Site 18
S239
K
E
W
Q
R
L
Q
S
N
P
H
L
K
E
G
Site 19
S250
L
K
E
G
S
V
T
S
V
N
L
T
K
L
E
Site 20
T315
K
W
M
H
P
Q
V
T
P
T
D
D
S
N
P
Site 21
Y351
P
A
A
T
D
N
R
Y
I
R
A
V
G
V
P
Site 22
T368
G
F
S
P
M
N
R
T
P
V
L
L
H
D
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation