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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PPARD
Full Name:
Peroxisome proliferator-activated receptor delta
Alias:
NR1C2; NUC1; NUCI; Nuclear hormone receptor 1; PPAR- beta; PPARB; PPAR-delta
Type:
Nucleus protein
Mass (Da):
49903
Number AA:
441
UniProt ID:
Q03181
International Prot ID:
IPI00009330
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0008144
GO:0070539
GO:0043565
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0008366
GO:0008203
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S39
G
P
Q
H
A
L
P
S
S
S
Y
T
D
L
S
Site 2
S40
P
Q
H
A
L
P
S
S
S
Y
T
D
L
S
R
Site 3
S41
Q
H
A
L
P
S
S
S
Y
T
D
L
S
R
S
Site 4
Y42
H
A
L
P
S
S
S
Y
T
D
L
S
R
S
S
Site 5
T43
A
L
P
S
S
S
Y
T
D
L
S
R
S
S
S
Site 6
S46
S
S
S
Y
T
D
L
S
R
S
S
S
P
P
S
Site 7
S48
S
Y
T
D
L
S
R
S
S
S
P
P
S
L
L
Site 8
S49
Y
T
D
L
S
R
S
S
S
P
P
S
L
L
D
Site 9
S50
T
D
L
S
R
S
S
S
P
P
S
L
L
D
Q
Site 10
S53
S
R
S
S
S
P
P
S
L
L
D
Q
L
Q
M
Site 11
S82
R
V
C
G
D
K
A
S
G
F
H
Y
G
V
H
Site 12
Y86
D
K
A
S
G
F
H
Y
G
V
H
A
C
E
G
Site 13
T101
C
K
G
F
F
R
R
T
I
R
M
K
L
E
Y
Site 14
Y108
T
I
R
M
K
L
E
Y
E
K
C
E
R
S
C
Site 15
T161
R
K
L
V
A
G
L
T
A
N
E
G
S
Q
Y
Site 16
Y168
T
A
N
E
G
S
Q
Y
N
P
Q
V
A
D
L
Site 17
Y183
K
A
F
S
K
H
I
Y
N
A
Y
L
K
N
F
Site 18
Y186
S
K
H
I
Y
N
A
Y
L
K
N
F
N
M
T
Site 19
T208
L
T
G
K
A
S
H
T
A
P
F
V
I
H
D
Site 20
T218
F
V
I
H
D
I
E
T
L
W
Q
A
E
K
G
Site 21
T253
F
Y
R
C
Q
C
T
T
V
E
T
V
R
E
L
Site 22
T256
C
Q
C
T
T
V
E
T
V
R
E
L
T
E
F
Site 23
T261
V
E
T
V
R
E
L
T
E
F
A
K
S
I
P
Site 24
S266
E
L
T
E
F
A
K
S
I
P
S
F
S
S
L
Site 25
S272
K
S
I
P
S
F
S
S
L
F
L
N
D
Q
V
Site 26
T313
A
N
G
S
G
F
V
T
R
E
F
L
R
S
L
Site 27
S319
V
T
R
E
F
L
R
S
L
R
K
P
F
S
D
Site 28
S325
R
S
L
R
K
P
F
S
D
I
I
E
P
K
F
Site 29
Y394
A
N
H
P
D
A
Q
Y
L
F
P
K
L
L
Q
Site 30
T423
M
M
Q
R
I
K
K
T
E
T
E
T
S
L
H
Site 31
S428
K
K
T
E
T
E
T
S
L
H
P
L
L
Q
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation