KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
LMNB2
Full Name:
Lamin-B2
Alias:
LMN2
Type:
Cytoskeletal protein
Mass (Da):
67689
Number AA:
600
UniProt ID:
Q03252
International Prot ID:
IPI00009771
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005637
GO:0005652
Uniprot
OncoNet
Molecular Function:
GO:0005198
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T14
G
R
A
G
G
P
A
T
P
L
S
P
T
R
L
Site 2
S17
G
G
P
A
T
P
L
S
P
T
R
L
S
R
L
Site 3
T19
P
A
T
P
L
S
P
T
R
L
S
R
L
Q
E
Site 4
S22
P
L
S
P
T
R
L
S
R
L
Q
E
K
E
E
Site 5
Y40
L
N
D
R
L
A
H
Y
I
D
R
V
R
A
L
Site 6
S59
D
R
L
L
L
K
I
S
E
K
E
E
V
T
T
Site 7
T65
I
S
E
K
E
E
V
T
T
R
E
V
S
G
I
Site 8
T66
S
E
K
E
E
V
T
T
R
E
V
S
G
I
K
Site 9
S70
E
V
T
T
R
E
V
S
G
I
K
A
L
Y
E
Site 10
T90
A
R
R
V
L
D
E
T
A
R
E
R
A
R
L
Site 11
S114
E
L
D
E
V
N
K
S
A
K
K
R
E
G
E
Site 12
T123
K
K
R
E
G
E
L
T
V
A
Q
G
R
V
K
Site 13
S134
G
R
V
K
D
L
E
S
L
F
H
R
S
E
V
Site 14
S148
V
E
L
A
A
A
L
S
D
K
R
G
L
E
S
Site 15
S155
S
D
K
R
G
L
E
S
D
V
A
E
L
R
A
Site 16
S194
D
L
E
N
R
C
Q
S
L
Q
E
E
L
D
F
Site 17
S204
E
E
L
D
F
R
K
S
V
F
E
E
E
V
R
Site 18
T213
F
E
E
E
V
R
E
T
R
R
R
H
E
R
R
Site 19
S226
R
R
L
V
E
V
D
S
S
R
Q
Q
E
Y
D
Site 20
S227
R
L
V
E
V
D
S
S
R
Q
Q
E
Y
D
F
Site 21
S245
Q
A
L
E
E
L
R
S
Q
H
D
E
Q
V
R
Site 22
Y254
H
D
E
Q
V
R
L
Y
K
L
E
L
E
Q
T
Site 23
T261
Y
K
L
E
L
E
Q
T
Y
Q
A
K
L
D
S
Site 24
S268
T
Y
Q
A
K
L
D
S
A
K
L
S
S
D
Q
Site 25
S272
K
L
D
S
A
K
L
S
S
D
Q
N
D
K
A
Site 26
S281
D
Q
N
D
K
A
A
S
A
A
R
E
E
L
K
Site 27
S296
E
A
R
M
R
L
E
S
L
S
Y
Q
L
S
G
Site 28
S298
R
M
R
L
E
S
L
S
Y
Q
L
S
G
L
Q
Site 29
Y299
M
R
L
E
S
L
S
Y
Q
L
S
G
L
Q
K
Site 30
S302
E
S
L
S
Y
Q
L
S
G
L
Q
K
Q
A
S
Site 31
S309
S
G
L
Q
K
Q
A
S
A
A
E
D
R
I
R
Site 32
T341
D
A
K
E
Q
E
M
T
E
M
R
D
V
M
Q
Site 33
Y354
M
Q
Q
Q
L
A
E
Y
Q
E
L
L
D
V
K
Site 34
Y371
L
D
M
E
I
N
A
Y
R
K
L
L
E
G
E
Site 35
S385
E
E
E
R
L
K
L
S
P
S
P
S
S
R
V
Site 36
S387
E
R
L
K
L
S
P
S
P
S
S
R
V
T
V
Site 37
S389
L
K
L
S
P
S
P
S
S
R
V
T
V
S
R
Site 38
S390
K
L
S
P
S
P
S
S
R
V
T
V
S
R
A
Site 39
T393
P
S
P
S
S
R
V
T
V
S
R
A
T
S
S
Site 40
S395
P
S
S
R
V
T
V
S
R
A
T
S
S
S
S
Site 41
T398
R
V
T
V
S
R
A
T
S
S
S
S
G
S
L
Site 42
S399
V
T
V
S
R
A
T
S
S
S
S
G
S
L
S
Site 43
S400
V
T
V
S
R
A
T
S
S
S
S
G
S
L
S
Site 44
S401
V
S
R
A
T
S
S
S
S
G
S
L
S
A
T
Site 45
S402
S
R
A
T
S
S
S
S
G
S
L
S
A
T
G
Site 46
S404
A
T
S
S
S
S
G
S
L
S
A
T
G
R
L
Site 47
S406
S
S
S
S
G
S
L
S
A
T
G
R
L
G
R
Site 48
T408
S
S
G
S
L
S
A
T
G
R
L
G
R
S
K
Site 49
S414
A
T
G
R
L
G
R
S
K
R
K
R
L
E
V
Site 50
S427
E
V
E
E
P
L
G
S
G
P
S
V
L
G
T
Site 51
S430
E
P
L
G
S
G
P
S
V
L
G
T
G
T
G
Site 52
T434
S
G
P
S
V
L
G
T
G
T
G
G
S
G
G
Site 53
S439
L
G
T
G
T
G
G
S
G
G
F
H
L
A
Q
Site 54
S451
L
A
Q
Q
A
S
A
S
G
S
V
S
I
E
E
Site 55
S453
Q
Q
A
S
A
S
G
S
V
S
I
E
E
I
D
Site 56
S455
A
S
A
S
G
S
V
S
I
E
E
I
D
L
E
Site 57
S472
F
V
Q
L
K
N
N
S
D
K
D
Q
S
L
G
Site 58
S477
N
N
S
D
K
D
Q
S
L
G
N
W
R
I
K
Site 59
Y495
L
E
G
E
E
I
A
Y
K
F
T
P
K
Y
I
Site 60
T498
E
E
I
A
Y
K
F
T
P
K
Y
I
L
R
A
Site 61
Y501
A
Y
K
F
T
P
K
Y
I
L
R
A
G
Q
M
Site 62
S524
G
V
A
H
S
P
P
S
T
L
V
W
K
G
Q
Site 63
T525
V
A
H
S
P
P
S
T
L
V
W
K
G
Q
S
Site 64
S533
L
V
W
K
G
Q
S
S
W
G
T
G
E
S
F
Site 65
T536
K
G
Q
S
S
W
G
T
G
E
S
F
R
T
V
Site 66
S539
S
S
W
G
T
G
E
S
F
R
T
V
L
V
N
Site 67
T542
G
T
G
E
S
F
R
T
V
L
V
N
A
D
G
Site 68
T556
G
E
E
V
A
M
R
T
V
K
K
S
S
V
M
Site 69
S560
A
M
R
T
V
K
K
S
S
V
M
R
E
N
E
Site 70
S561
M
R
T
V
K
K
S
S
V
M
R
E
N
E
N
Site 71
T592
H
Q
Q
G
D
P
R
T
T
S
R
G
C
Y
V
Site 72
T593
Q
Q
G
D
P
R
T
T
S
R
G
C
Y
V
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation