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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CFHR1
Full Name:
Complement factor H-related protein 1
Alias:
H factor-like protein 1;H36
Type:
Mass (Da):
37651
Number AA:
330
UniProt ID:
Q03591
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y34
K
I
N
H
G
I
L
Y
D
E
E
K
Y
K
P
Site 2
Y39
I
L
Y
D
E
E
K
Y
K
P
F
S
Q
V
P
Site 3
S43
E
E
K
Y
K
P
F
S
Q
V
P
T
G
E
V
Site 4
T47
K
P
F
S
Q
V
P
T
G
E
V
F
Y
Y
S
Site 5
Y52
V
P
T
G
E
V
F
Y
Y
S
C
E
Y
N
F
Site 6
Y53
P
T
G
E
V
F
Y
Y
S
C
E
Y
N
F
V
Site 7
Y57
V
F
Y
Y
S
C
E
Y
N
F
V
S
P
S
K
Site 8
S61
S
C
E
Y
N
F
V
S
P
S
K
S
F
W
T
Site 9
S78
T
C
T
E
E
G
W
S
P
T
P
K
C
L
R
Site 10
T80
T
E
E
G
W
S
P
T
P
K
C
L
R
L
C
Site 11
S97
P
F
V
E
N
G
H
S
E
S
S
G
Q
T
H
Site 12
T109
Q
T
H
L
E
G
D
T
V
Q
I
I
C
N
T
Site 13
S135
S
C
V
E
R
G
W
S
T
P
P
K
C
R
S
Site 14
T136
C
V
E
R
G
W
S
T
P
P
K
C
R
S
T
Site 15
S142
S
T
P
P
K
C
R
S
T
D
T
S
C
V
N
Site 16
T143
T
P
P
K
C
R
S
T
D
T
S
C
V
N
P
Site 17
T145
P
K
C
R
S
T
D
T
S
C
V
N
P
P
T
Site 18
S146
K
C
R
S
T
D
T
S
C
V
N
P
P
T
V
Site 19
S160
V
Q
N
A
H
I
L
S
R
Q
M
S
K
Y
P
Site 20
S164
H
I
L
S
R
Q
M
S
K
Y
P
S
G
E
R
Site 21
Y166
L
S
R
Q
M
S
K
Y
P
S
G
E
R
V
R
Site 22
S168
R
Q
M
S
K
Y
P
S
G
E
R
V
R
Y
E
Site 23
Y174
P
S
G
E
R
V
R
Y
E
C
R
S
P
Y
E
Site 24
S178
R
V
R
Y
E
C
R
S
P
Y
E
M
F
G
D
Site 25
Y180
R
Y
E
C
R
S
P
Y
E
M
F
G
D
E
E
Site 26
S204
E
P
P
Q
C
K
D
S
T
G
K
C
G
P
P
Site 27
T205
P
P
Q
C
K
D
S
T
G
K
C
G
P
P
P
Site 28
T220
P
I
D
N
G
D
I
T
S
F
P
L
S
V
Y
Site 29
S231
L
S
V
Y
A
P
A
S
S
V
E
Y
Q
C
Q
Site 30
S232
S
V
Y
A
P
A
S
S
V
E
Y
Q
C
Q
N
Site 31
Y235
A
P
A
S
S
V
E
Y
Q
C
Q
N
L
Y
Q
Site 32
Y241
E
Y
Q
C
Q
N
L
Y
Q
L
E
G
N
K
R
Site 33
Y289
W
T
A
K
Q
K
L
Y
L
R
T
G
E
S
A
Site 34
Y304
E
F
V
C
K
R
G
Y
R
L
S
S
R
S
H
Site 35
S307
C
K
R
G
Y
R
L
S
S
R
S
H
T
L
R
Site 36
S308
K
R
G
Y
R
L
S
S
R
S
H
T
L
R
T
Site 37
S310
G
Y
R
L
S
S
R
S
H
T
L
R
T
T
C
Site 38
T312
R
L
S
S
R
S
H
T
L
R
T
T
C
W
D
Site 39
T315
S
R
S
H
T
L
R
T
T
C
W
D
G
K
L
Site 40
T316
R
S
H
T
L
R
T
T
C
W
D
G
K
L
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation