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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CEBPZ
Full Name:
CCAAT/enhancer-binding protein zeta
Alias:
CBF; CBF2; CCAAT/enhancer binding protein (C/EBP) zeta; CCAAT-binding factor; CCAAT-box-binding transcription factor; CTF2
Type:
Transcription protein
Mass (Da):
120988
Number AA:
1054
UniProt ID:
Q03701
International Prot ID:
IPI00306723
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003677
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006350
GO:0006351
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T33
D
E
E
D
E
D
N
T
S
E
A
E
N
G
F
Site 2
S34
E
E
D
E
D
N
T
S
E
A
E
N
G
F
S
Site 3
S41
S
E
A
E
N
G
F
S
L
E
E
V
L
R
L
Site 4
Y96
Q
N
L
N
L
A
K
Y
T
K
A
S
L
I
E
Site 5
S100
L
A
K
Y
T
K
A
S
L
I
E
E
D
E
P
Site 6
S131
N
N
K
N
T
A
E
S
Q
R
T
S
V
N
K
Site 7
S135
T
A
E
S
Q
R
T
S
V
N
K
V
K
N
K
Site 8
S149
K
N
R
P
E
P
H
S
D
E
N
G
S
T
T
Site 9
T155
H
S
D
E
N
G
S
T
T
P
K
V
K
K
D
Site 10
T156
S
D
E
N
G
S
T
T
P
K
V
K
K
D
K
Site 11
T174
F
E
F
F
E
R
Q
T
L
L
L
R
P
G
G
Site 12
Y188
G
K
W
Y
D
L
E
Y
S
N
E
Y
S
L
K
Site 13
S189
K
W
Y
D
L
E
Y
S
N
E
Y
S
L
K
P
Site 14
Y192
D
L
E
Y
S
N
E
Y
S
L
K
P
Q
P
Q
Site 15
S193
L
E
Y
S
N
E
Y
S
L
K
P
Q
P
Q
D
Site 16
S203
P
Q
P
Q
D
V
V
S
K
Y
K
T
L
A
Q
Site 17
Y205
P
Q
D
V
V
S
K
Y
K
T
L
A
Q
K
L
Site 18
T207
D
V
V
S
K
Y
K
T
L
A
Q
K
L
Y
Q
Site 19
Y213
K
T
L
A
Q
K
L
Y
Q
H
E
I
N
L
F
Site 20
S222
H
E
I
N
L
F
K
S
K
T
N
S
Q
K
G
Site 21
T224
I
N
L
F
K
S
K
T
N
S
Q
K
G
A
S
Site 22
S226
L
F
K
S
K
T
N
S
Q
K
G
A
S
S
T
Site 23
S241
W
M
K
A
I
V
S
S
G
T
L
G
D
R
M
Site 24
T295
T
F
K
E
L
L
I
T
D
L
L
P
D
N
R
Site 25
S308
N
R
K
L
R
I
F
S
Q
R
P
F
D
K
L
Site 26
S319
F
D
K
L
E
Q
L
S
S
G
N
K
D
S
R
Site 27
S320
D
K
L
E
Q
L
S
S
G
N
K
D
S
R
D
Site 28
S325
L
S
S
G
N
K
D
S
R
D
R
R
L
I
L
Site 29
Y334
D
R
R
L
I
L
W
Y
F
E
H
Q
L
K
H
Site 30
T400
D
P
Q
N
R
I
A
T
K
A
S
H
L
L
E
Site 31
S431
V
E
R
L
L
F
R
S
N
I
S
S
K
A
Q
Site 32
S435
L
F
R
S
N
I
S
S
K
A
Q
Y
Y
A
I
Site 33
S451
F
L
N
Q
M
A
L
S
H
E
E
S
E
L
A
Site 34
S455
M
A
L
S
H
E
E
S
E
L
A
N
K
L
I
Site 35
S480
V
K
K
K
D
V
E
S
K
M
L
S
A
L
L
Site 36
Y494
L
T
G
V
N
R
A
Y
P
Y
S
Q
T
G
D
Site 37
Y496
G
V
N
R
A
Y
P
Y
S
Q
T
G
D
D
K
Site 38
S497
V
N
R
A
Y
P
Y
S
Q
T
G
D
D
K
V
Site 39
S536
L
L
F
Q
V
M
N
S
Q
Q
T
I
S
D
R
Site 40
S541
M
N
S
Q
Q
T
I
S
D
R
Y
Y
T
A
L
Site 41
Y544
Q
Q
T
I
S
D
R
Y
Y
T
A
L
Y
R
K
Site 42
Y545
Q
T
I
S
D
R
Y
Y
T
A
L
Y
R
K
M
Site 43
T546
T
I
S
D
R
Y
Y
T
A
L
Y
R
K
M
L
Site 44
Y549
D
R
Y
Y
T
A
L
Y
R
K
M
L
D
P
G
Site 45
Y571
A
M
F
L
N
L
V
Y
K
S
L
K
A
D
I
Site 46
T594
V
K
R
L
L
Q
V
T
C
Q
Q
M
P
P
F
Site 47
S621
K
A
K
P
G
L
R
S
Q
L
D
D
H
P
E
Site 48
S629
Q
L
D
D
H
P
E
S
D
D
E
E
N
F
I
Site 49
T665
K
K
L
E
T
E
E
T
V
P
E
T
D
V
E
Site 50
T669
T
E
E
T
V
P
E
T
D
V
E
T
K
K
P
Site 51
T673
V
P
E
T
D
V
E
T
K
K
P
E
V
A
S
Site 52
Y696
G
G
K
Q
L
N
K
Y
D
P
F
S
R
N
P
Site 53
S720
L
W
E
L
K
K
L
S
V
H
F
H
P
S
V
Site 54
Y739
K
T
I
L
Q
G
N
Y
I
Q
Y
S
G
D
P
Site 55
S743
Q
G
N
Y
I
Q
Y
S
G
D
P
L
Q
D
F
Site 56
T751
G
D
P
L
Q
D
F
T
L
M
R
F
L
D
R
Site 57
Y761
R
F
L
D
R
F
V
Y
R
N
P
K
P
H
K
Site 58
S775
K
G
K
E
N
T
D
S
V
V
M
Q
P
K
R
Site 59
S805
E
F
L
A
K
E
E
S
Q
I
P
V
D
E
V
Site 60
Y818
E
V
F
F
H
R
Y
Y
K
K
V
A
V
K
E
Site 61
S835
K
R
D
A
D
E
E
S
I
E
D
V
D
D
E
Site 62
T850
E
F
E
E
L
I
D
T
F
E
D
D
N
C
F
Site 63
T881
T
K
G
A
K
D
N
T
L
D
E
D
S
E
G
Site 64
S886
D
N
T
L
D
E
D
S
E
G
S
D
D
E
L
Site 65
S902
N
L
D
D
D
E
V
S
L
G
S
M
D
D
E
Site 66
T920
E
V
D
E
D
G
G
T
F
M
D
V
L
D
D
Site 67
S929
M
D
V
L
D
D
E
S
E
S
V
P
E
L
E
Site 68
S931
V
L
D
D
E
S
E
S
V
P
E
L
E
V
H
Site 69
T943
E
V
H
S
K
V
S
T
K
K
S
K
R
K
G
Site 70
S946
S
K
V
S
T
K
K
S
K
R
K
G
T
D
D
Site 71
T951
K
K
S
K
R
K
G
T
D
D
F
D
F
A
G
Site 72
S959
D
D
F
D
F
A
G
S
F
Q
G
P
R
K
K
Site 73
S973
K
K
R
N
L
N
D
S
S
L
F
V
S
A
E
Site 74
S974
K
R
N
L
N
D
S
S
L
F
V
S
A
E
E
Site 75
S978
N
D
S
S
L
F
V
S
A
E
E
F
G
H
L
Site 76
S1030
L
H
N
R
D
A
K
S
I
I
K
K
K
K
H
Site 77
T1045
F
K
K
K
R
I
K
T
T
Q
K
T
K
K
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation